DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SPH93 and XB5723326

DIOPT Version :9

Sequence 1:	NP_609840.1	Gene:	SPH93 / 35049	FlyBaseID:	FBgn0032638	Length:	494	Species:	Drosophila melanogaster
Sequence 2:	NP_001037931.1	Gene:	XB5723326 / 733551	XenbaseID:	XB-GENE-5723327	Length:	349	Species:	Xenopus tropicalis

Alignment Length:	279	Identity:	79/279 - (28%)
Similarity:	130/279 - (46%)	Gaps:	48/279 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   232 SCG---------MSNANGLQMVEGITIDQARPAQYPWAVAIFHNGQ----YLAGGSLIQPNVVLT 283
            :||         .|.:..|..|||         ::||.|:|....:    ::..|:::....::|
Frog     2 ACGNRPFYTEVKASYSTELNPVEG---------KWPWIVSIQKKVELGYKHICAGTILNNEWIIT 57

  Fly   284 VAH-----RVITIETELVVRAGDWDLKSDREIFL-SEQREVERAVIHEGFDFKSGANNLALLFLN 342
            .||     :.....|.|.|..|.:.|.   ||.| ::.|.|::.:.|:.:|..:.:|::||:.|:
Frog    58 AAHCFKDWKEGDPTTPLRVLLGTFYLS---EIGLRTQSRGVKQLIKHDQYDPITESNDIALIQLD 119

  Fly   343 SPFKLNDHIRTICLPTPNKSFAGRR----CTVAGWGKMRYEDQRYSTVLKKVQLLVVNRNVCEKF 403
            ...:.:|||:..|.|   |..|..:    |::||||.........|..|::.|:..::...|.|:
Frog   120 KQVEFSDHIQQACFP---KESADLKDLIDCSIAGWGAQGKHLDEPSQFLQEAQVERIDTKHCNKW 181

  Fly   404 LRSTRLGAKFELPKNIICAGGELGRD-TCTGDGGSALFCSIGGENSGVYEQAGIVNWGVGCGQEG 467
            .:..       |.:|.:|||...|.: ||.||.||.|.|..  :.:.||...||:|||.||||..
Frog   182 YQGI-------LGENHLCAGHRKGPEKTCNGDRGSPLMCRT--KKNNVYSVIGILNWGSGCGQTR 237

  Fly   468 IPAIYTEVSKFTNWITEKL 486
            .|.:|:.:.....||.||:
Frog   238 SPGVYSPIQSHIKWIVEKV 256

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SPH93	NP_609840.1	GRP	<136..189	CDD:254089
		Tryp_SPc	250..485	CDD:238113	70/249 (28%)
		Tryp_SPc	252..482	CDD:214473	68/244 (28%)
XB5723326	NP_001037931.1	Tryp_SPc	25..252	CDD:214473	69/250 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910