DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SPH93 and Prss36

DIOPT Version :9

Sequence 1:	NP_609840.1	Gene:	SPH93 / 35049	FlyBaseID:	FBgn0032638	Length:	494	Species:	Drosophila melanogaster
Sequence 2:	XP_038942639.1	Gene:	Prss36 / 497040	RGDID:	1593186	Length:	874	Species:	Rattus norvegicus

Alignment Length:	287	Identity:	87/287 - (30%)
Similarity:	139/287 - (48%)	Gaps:	27/287 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   218 NPTTNVGSSELLSPS--------CGMSNANGLQMVEGITIDQARPAQYPWAVAIFHNGQYLAGGS 274
            :||........:||:        ||....:. ::|.|   ..|.|..:||.|::.|.|.::.|||
  Rat    27 SPTPGAFQDSAVSPTQGEFEDLDCGRPEPSS-RIVGG---SDAHPGTWPWQVSLHHGGGHICGGS 87

  Fly   275 LIQPNVVLTVAHRVITIETELVVRAGDWDL-----KSDREIFLSEQREVERAVIHEGFDFKSGAN 334
            ||.|:.||:.||..:|..|  :..|.:|.:     ..|..:..:..|.|...::.:.:.......
  Rat    88 LIAPSWVLSAAHCFVTNGT--LEPADEWSVLLGVHSQDGPLEGAHMRSVATILVPDNYSRVELGA 150

  Fly   335 NLALLFLNSPFKLNDHIRTICLPTPNKSFA-GRRCTVAGWGKMRYEDQ-RYSTVLKKVQLLVVNR 397
            :||||.|.||.||...::.:|||..:..|| |..|...|||.::..|. ....||::|:|.::..
  Rat   151 DLALLRLASPAKLGPSVKPVCLPRASHLFAHGTACWATGWGDVQESDPLPVPWVLQEVELKLLGE 215

  Fly   398 NVCE-KFLRSTRLGAKFELPKNIICAGGELG-RDTCTGDGGSALFCSIGGENSGVYEQAGIVNWG 460
            ..|: .:.|........:|...::|||...| ||||.||.|..|.|    |:.|.:..|||.::|
  Rat   216 TACQCLYSRPGPFNLTLQLLPGMLCAGYPEGRRDTCQGDSGGPLVC----EDGGRWFLAGITSFG 276

  Fly   461 VGCGQEGIPAIYTEVSKFTNWITEKLL 487
            .|||:...|.::|.|:.:.:||.|.::
  Rat   277 FGCGRRNRPGVFTAVAHYESWIREHVM 303

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SPH93	NP_609840.1	GRP	<136..189	CDD:254089
		Tryp_SPc	250..485	CDD:238113	78/243 (32%)
		Tryp_SPc	252..482	CDD:214473	76/238 (32%)
Prss36	XP_038942639.1	Tryp_SPc	59..301	CDD:238113	80/250 (32%)
		Tryp_SPc	338..532	CDD:419748
		Tryp_SPc	607..802	CDD:419748
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910