DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SPH93 and CG14990

DIOPT Version :9

Sequence 1:	NP_609840.1	Gene:	SPH93 / 35049	FlyBaseID:	FBgn0032638	Length:	494	Species:	Drosophila melanogaster
Sequence 2:	NP_647856.2	Gene:	CG14990 / 38486	FlyBaseID:	FBgn0035496	Length:	322	Species:	Drosophila melanogaster

Alignment Length:	299	Identity:	143/299 - (47%)
Similarity:	183/299 - (61%)	Gaps:	21/299 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   214 NNGGNPTTNVGSS--ELLSPS----CGMSNANGLQMVEGITIDQARPAQYPWAVAIFHNGQYLAG 272
            |.||.|....|.|  |.|.|.    |||||.|||.....:..|.:.|.|:||.||:|..|:|...
  Fly    23 NEGGAPGIFNGMSFTENLQPDPNQVCGMSNPNGLVANVKVPKDYSTPGQFPWVVALFSQGKYFGA 87

  Fly   273 GSLIQPNVVLTVAHRVI-TIETELVVRAGDWDLKSDREIFLSEQREVERAVIHEGFDFKSGANNL 336
            ||||.|.||||.|..|: ..:.|:|||||:|:.....|...||.|.|.|.|.|..|.:..||||:
  Fly    88 GSLIAPEVVLTAASIVVGKTDAEIVVRAGEWNTGQRSEFLPSEDRPVARVVQHREFSYLLGANNI 152

  Fly   337 ALLFLNSPFKLNDHIRTICLPTPNKSFAGRRCTVAGWGKMRYEDQRYSTVLKKVQLLVVNRNVCE 401
            |||||.:||:|..||||||||:..:||..:||.|.||||:.:.|:.||.:.||::|.::||..|:
  Fly   153 ALLFLANPFELKSHIRTICLPSQGRSFDQKRCLVTGWGKVAFNDENYSNIQKKIELPMINRAQCQ 217

  Fly   402 KFLRSTRLGAKFELPKNIICAGGELGRDTCTGDGGSALFCSIGGENSGVYEQAGIVNWGVGCGQE 466
            ..||:||||..|:||.::||||||.....|.|||||||||.:..:.|. ||||||||||:||.:|
  Fly   218 DQLRNTRLGVSFDLPASLICAGGEKDAGDCLGDGGSALFCPMEADPSR-YEQAGIVNWGIGCQEE 281

  Fly   467 GIPAIYTEVSKFTNWITEKL-------------LPFDYR 492
            .:||:||.|..|.:||.|.:             ||.:|:
  Fly   282 NVPAVYTNVEMFRDWIYEHMAQNSNSVPFAAGQLPSNYK 320

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SPH93	NP_609840.1	GRP	<136..189	CDD:254089
		Tryp_SPc	250..485	CDD:238113	122/235 (52%)
		Tryp_SPc	252..482	CDD:214473	119/230 (52%)
CG14990	NP_647856.2	Tryp_SPc	67..300	CDD:238113	121/233 (52%)
CG14990	NP_647856.2	Tryp_SPc	67..297	CDD:214473	119/230 (52%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45471496
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BM7R
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	132	1.000	Inparanoid score	I4490
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D23222at50557
OrthoFinder	1	1.000	-	-		FOG0003848
OrthoInspector	1	1.000	-	-		mtm8716
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24256
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	8	7.900