DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment SPH93 and CG31220

DIOPT Version :9

Sequence 1:	NP_609840.1	Gene:	SPH93 / 35049	FlyBaseID:	FBgn0032638	Length:	494	Species:	Drosophila melanogaster
Sequence 2:	NP_732440.2	Gene:	CG31220 / 326126	FlyBaseID:	FBgn0051220	Length:	363	Species:	Drosophila melanogaster

Alignment Length:	288	Identity:	83/288 - (28%)
Similarity:	117/288 - (40%)	Gaps:	47/288 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   231 PSCGMSNANGLQMVEGITIDQARPAQYPW-AVAIFHNGQYL---------AGGSLIQPNVVLTVA 285
            |.||...... :::.|   .:....:||| |:.::.|....         .|||||....|||.|
  Fly    93 PDCGKPQTTN-RVIGG---TEPNLNEYPWLAMLLYRNRSAFNPDRELVPSCGGSLINTRYVLTAA 153

  Fly   286 HRVITIETELV-----VRAGDWDLKSDREIFLSEQR----------EVERAVIHEGFD-----FK 330
            |.|    |:.|     ||.|:.....:.:......|          :||....|..:|     |:
  Fly   154 HCV----TDTVLQIQRVRLGEHTTSHNPDCISRGARIVCAPTHLDIDVESITSHNDYDPANYTFR 214

  Fly   331 SGANNLALLFLNSPFKLNDHIRTICLPTPNKSFAGRRCTVAGWGKMRYEDQRYSTVLKKVQLLVV 395
               |::||:.|..|.:.......||:....:|....:..||||||....|.. |.|||...:.|.
  Fly   215 ---NDIALVRLKEPVRYTMAYYPICVLDYPRSLMKFKMYVAGWGKTGMFDTG-SKVLKHAAVKVR 275

  Fly   396 NRNVCEKFLRSTRLGAKFELPKNIICAGGELGRDTCTGDGGSALFCSIGGENSGVYEQAGIVNWG 460
            ....|.:.......|.:|:     |||||...|.||.||.||.|..:.|.....:...|||.::|
  Fly   276 KPEECSEKYAHRHFGPRFQ-----ICAGGLDNRGTCDGDSGSPLMGTSGRSYETITFLAGITSYG 335

  Fly   461 VGCGQEGIPAIYTEVSKFTNWITEKLLP 488
            ..||..|.|:::|..:||..||...|.|
  Fly   336 GPCGTIGWPSVFTRTAKFYKWIRAHLRP 363

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SPH93	NP_609840.1	GRP	<136..189	CDD:254089
		Tryp_SPc	250..485	CDD:238113	77/264 (29%)
		Tryp_SPc	252..482	CDD:214473	75/259 (29%)
CG31220	NP_732440.2	Tryp_SPc	103..357	CDD:214473	76/269 (28%)
CG31220	NP_732440.2	Tryp_SPc	104..360	CDD:238113	78/271 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910