DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SPH93 and Prss3b

DIOPT Version :9

Sequence 1:	NP_609840.1	Gene:	SPH93 / 35049	FlyBaseID:	FBgn0032638	Length:	494	Species:	Drosophila melanogaster
Sequence 2:	NP_775150.1	Gene:	Prss3b / 286911	RGDID:	708437	Length:	247	Species:	Rattus norvegicus

Alignment Length:	230	Identity:	70/230 - (30%)
Similarity:	120/230 - (52%)	Gaps:	27/230 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   258 PWAVAIFHNGQYLAGGSLIQPNVVLTVAHRVITIETELVVRAGDW--DLKSDREIFLSEQREVER 320
            |:.|:: :.|.:..|||||....|::.||   ..::.:.||.|:.  |:....|.|:    :..:
  Rat    37 PYQVSL-NAGYHFCGGSLINSQWVVSAAH---CYKSRIQVRLGEHNIDVVEGGEQFI----DAAK 93

  Fly   321 AVIHEGFDFKSGANNLALLFLNSPFKLNDHIRTICLPTPNKSFAGRRCTVAGWGKMRYEDQRYST 385
            .:.|..::..:..|::.|:.||||..||..:.|:.||....| :|.:|.|:|||........|.:
  Rat    94 IIRHPSYNANTFDNDIMLIKLNSPATLNSRVSTVSLPRSCGS-SGTKCLVSGWGNTLSSGTNYPS 157

  Fly   386 VLKKVQLLVVNRNVCEKFLRSTRLGAKFELPKNIICAGG-ELGRDTCTGDGGSALFCSIGGENSG 449
            :|:.:...|::.:.|    :|:..|   ::..|:.|.|. |.|:|:|.||.|..:.|:  |:..|
  Rat   158 LLQCLDAPVLSDSSC----KSSYPG---KITSNMFCLGFLEGGKDSCQGDSGGPVVCN--GQLQG 213

  Fly   450 VYEQAGIVNWGVGCGQEGIPAIYTEVSKFTNWITE 484
            |      |:||.||.|:|.|.:||:|..:.|||.:
  Rat   214 V------VSWGYGCAQKGKPGVYTKVCNYVNWIQQ 242

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SPH93	NP_609840.1	GRP	<136..189	CDD:254089
		Tryp_SPc	250..485	CDD:238113	70/230 (30%)
		Tryp_SPc	252..482	CDD:214473	68/226 (30%)
Prss3b	NP_775150.1	Tryp_SPc	24..240	CDD:214473	68/226 (30%)
Prss3b	NP_775150.1	Tryp_SPc	25..243	CDD:238113	70/230 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910