Protein Alignment SPH93 and TPSD1

DIOPT Version :10

• Sequence 1: NP_609840.1
• Gene: SPH93 / 35049
• FlyBaseID: FBgn0032638
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_036349.1
• Gene: TPSD1 / 23430
• HGNCID: 14118
• Length: 242
• Species: Homo sapiens
• Alignment Length: 242
• Identity: 74/242 - (30%)
• Similarity: 115/242 - (47%)
• Gaps: 38/242 - (15%)

  Fly   223 VGSSELLSPSCGMSNANGLQMVEGITIDQARP-AQYPWAVAIFHNGQY---LAGGSLIQPNVVLT 283
            :.|...::|:.|.:    ||.. ||...|..| :::||.|::...|.|   ..|||||.|..|||
Human    19 LASPAYVAPAPGQA----LQQT-GIVGGQEAPRSKWPWQVSLRVRGPYWMHFCGGSLIHPQWVLT 78

  Fly   284 VAHRVITIETELVVRAGDWDLKSDREIFLSEQR--------EVERAVIHEGFDFKSGANNLALLF 340
            .||   .:|.::.      ||.:.| :.|.||.        .|.|.::|..|.......::|||.
Human    79 AAH---CVEPDIK------DLAALR-VQLREQHLYYQDQLLPVSRIIVHPQFYIIQTGADIALLE 133

  Fly   341 LNSPFKLNDHIRTICLPTPNKSF-AGRRCTVAGWGKMRYEDQRYST----VLKKVQLLVVNRNVC 400
            |..|..::.||.|:.||..:::| .|..|.|.|||.:   |.....    .||:|::.||..::|
Human   134 LEEPVNISSHIHTVTLPPASETFPPGMPCWVTGWGDV---DNNVHLPPPYPLKEVEVPVVENHLC 195

  Fly   401 E-KFLRSTRLGAKFELPK-NIICAGGELGRDTCTGDGGSALFCSIGG 445
            . ::......|..|::.: :::|||.| ..|:|.||.|..|.|.:.|
Human   196 NAEYHTGLHTGHSFQIVRDDMLCAGSE-NHDSCQGDSGGPLVCKVNG 241

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SPH93	NP_609840.1	Herpes_BLLF1	<78..>226	CDD:282904	0/2 (0%)
		Tryp_SPc	252..482	CDD:214473	66/213 (31%)
TPSD1	NP_036349.1	Tryp_SPc	38..242	CDD:238113	68/218 (31%)