DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SPH93 and AgaP_AGAP003248

DIOPT Version :9

Sequence 1:	NP_609840.1	Gene:	SPH93 / 35049	FlyBaseID:	FBgn0032638	Length:	494	Species:	Drosophila melanogaster
Sequence 2:	XP_312959.4	Gene:	AgaP_AGAP003248 / 1273921	VectorBaseID:	AGAP003248	Length:	296	Species:	Anopheles gambiae

Alignment Length:	288	Identity:	78/288 - (27%)
Similarity:	121/288 - (42%)	Gaps:	62/288 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   231 PSCGMSNANGLQMVEGITIDQARPAQYPWAVAIFH---NG--QYLAGGSLIQPNVVLTVAHRVIT 290
            |.||......|     ||...|:..:.||...|.:   ||  .||.|||||....|:|.||.|.:
Mosquito    38 PMCGNDAPERL-----ITSLVAQLDEAPWMALIEYWKPNGSLSYLCGGSLINERYVVTAAHCVTS 97

  Fly   291 IE---TELVVRAGDWDLKSDREIFLSEQRE------VERAVIHEGFDFKSGA----NNLALLFLN 342
            :.   |...:|.|:|||.:..:...|...:      |::..:||  |:||.:    |::||:.|:
Mosquito    98 LPQGWTVHRIRLGEWDLSTSEDCDHSRCNDAPIDVAVDKITVHE--DYKSPSRNHRNDIALIRLD 160

  Fly   343 SPFKLNDHIRTICLPT--PNKSFAGRRCTVAGWGKMRYEDQRYSTV-LKKVQL---LVVNRNVCE 401
            ......:.:..||||.  |.::...|.....||     .::.:..: .||:|:   ||..:|...
Mosquito   161 RQMHYTETVAPICLPQNGPLQTQRYRTMHSVGW-----IEENFGPIGGKKLQVEQDLVDFQNCSS 220

  Fly   402 KFLRS------TRLGAKFELPKNIICAGGELGRDTCTGDGGSALF--CSIGGENSGVYEQAGIVN 458
            .:|::      |:|....:....|..|||.|.:...   |...||  .|.||.|.|..|
Mosquito   221 NYLQASIALADTQLCVAQQKDNRIDIAGGPLMQRIA---GHWYLFGVASFGGRNYGTVE------ 276

  Fly   459 WGVGCGQEGIPAIYTEVSKFTNWITEKL 486
                     :|.:||.|.::.:||...:
Mosquito   277 ---------LPNVYTNVMEYVDWIESNI 295

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SPH93	NP_609840.1	GRP	<136..189	CDD:254089
		Tryp_SPc	250..485	CDD:238113	72/266 (27%)
		Tryp_SPc	252..482	CDD:214473	70/261 (27%)
AgaP_AGAP003248	XP_312959.4	Tryp_SPc	53..291	CDD:214473	70/262 (27%)
AgaP_AGAP003248	XP_312959.4	Tryp_SPc	54..294	CDD:238113	72/264 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910