DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SPH93 and F11

DIOPT Version :9

Sequence 1:	NP_609840.1	Gene:	SPH93 / 35049	FlyBaseID:	FBgn0032638	Length:	494	Species:	Drosophila melanogaster
Sequence 2:	NP_082342.1	Gene:	F11 / 109821	MGIID:	99481	Length:	624	Species:	Mus musculus

Alignment Length:	317	Identity:	92/317 - (29%)
Similarity:	139/317 - (43%)	Gaps:	50/317 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   190 YPTTNVGNPTNNGGNPTTNFGNPTNNGGNPTTNV----GSSELLSPSCGMSN----------ANG 240
            ||:..:.|..|..|......    ::.|:||..:    |.|......|.|.|          ..|
Mouse   333 YPSHRLCNERNRRGRCYLKL----SSNGSPTRILHGRGGISGYSLRLCKMDNVCTTKINPRVVGG 393

  Fly   241 LQMVEGITIDQARPAQYPWAVAIFHNGQYLAGGSLIQPNVVLTVAHRVITIETELVVR-----AG 300
            ...|.|         ::||.|.:..:..:|.|||:|....:||.||....|||...:|     ..
Mouse   394 AASVHG---------EWPWQVTLHISQGHLCGGSIIGNQWILTAAHCFSGIETPKKLRVYGGIVN 449

  Fly   301 DWDLKSDREIFLSEQREVERAVIHEGFDFKSGANNLALLFLNSPFKLNDHIRTICLPTP-NKSFA 364
            ..::......|     .|:..:||:.:.......::|||.|.|.....|..|.||||:. :::..
Mouse   450 QSEINEGTAFF-----RVQEMIIHDQYTTAESGYDIALLKLESAMNYTDFQRPICLPSKGDRNAV 509

  Fly   365 GRRCTVAGWGKMRYEDQRYSTVLKKVQLLVVNRNVCEKFLRSTRLGAKFELPKNIICAG-GELGR 428
            ...|.|.|||......:..|| |:|.::.:|:...|:...|      :.::...:|||| .|.|:
Mouse   510 HTECWVTGWGYTALRGEVQST-LQKAKVPLVSNEECQTRYR------RHKITNKMICAGYKEGGK 567

  Fly   429 DTCTGDGGSALFCSIGGENSGVYEQAGIVNWGVGCGQEGIPAIYTEVSKFTNWITEK 485
            |||.||.|..|.|    :.:||:...||.:||.||||:..|.:||.|:|:.:||.||
Mouse   568 DTCKGDSGGPLSC----KYNGVWHLVGITSWGEGCGQKERPGVYTNVAKYVDWILEK 620

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SPH93	NP_609840.1	GRP	<136..189	CDD:254089
		Tryp_SPc	250..485	CDD:238113	74/241 (31%)
		Tryp_SPc	252..482	CDD:214473	72/236 (31%)
F11	NP_082342.1	APPLE	20..103	CDD:128519
		APPLE	110..193	CDD:128519
		APPLE	200..283	CDD:128519
		APPLE	291..376	CDD:128519	10/46 (22%)
		Tryp_SPc	389..617	CDD:214473	75/252 (30%)
		Tryp_SPc	390..617	CDD:238113	75/251 (30%)
		Heparin-binding. /evidence=ECO:0000250	547..550		1/8 (13%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910