DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SPH93 and cela1.2

DIOPT Version :9

Sequence 1:	NP_609840.1	Gene:	SPH93 / 35049	FlyBaseID:	FBgn0032638	Length:	494	Species:	Drosophila melanogaster
Sequence 2:	NP_001307331.1	Gene:	cela1.2 / 100535584	ZFINID:	ZDB-GENE-050208-732	Length:	269	Species:	Danio rerio

Alignment Length:	250	Identity:	68/250 - (27%)
Similarity:	111/250 - (44%)	Gaps:	38/250 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   252 ARPAQYPWAVAIFHNG----QYLAGGSLIQPNVVLTVAHRVITIETELVVRAGDWDLKSDR--EI 310
            |:|..:||.:::.::.    .|...|:||:|..|:..||.|..:. :..|..||.|:.:..  |.
Zfish    36 AKPHSWPWQISLQYSDLGTYYYYCSGTLIRPGWVMVAAHCVEALR-KWTVALGDHDIYTHEGPEQ 99

  Fly   311 FLSEQREVERAVIHEGFDFKSGANN------LALLFLNSPFKLNDHIRTICLPTPNKSFA-GRRC 368
            ::|    |....||..::    .||      :|||.|:....|:.:::...||:..:... |..|
Zfish   100 YIS----VSEVFIHPNWN----PNNVAFGYDIALLRLSIDATLSSYVQVATLPSSGEILPYGHTC 156

  Fly   369 TVAGWGKMRYEDQ--RYSTVLKKVQLLVVNRNVCEKFLRSTRLGAKFELPKNIICAGGELGRDTC 431
            .:.|||   |.:.  ..|..||:..:.||:...|.   :....|:  .:.:.:|||||......|
Zfish   157 YITGWG---YTETGGSLSAQLKQAYMPVVDYETCS---QKDWWGS--SVKETMICAGGTTSMSAC 213

  Fly   432 TGDGGSALFCSIGGENSGVYEQAGIVNW--GVGCGQEGIPAIYTEVSKFTNWITE 484
            .||.||.|.|...|:    |...|:.::  ..||.....|..:|.||.:.|||.:
Zfish   214 HGDSGSPLNCLFNGK----YVVHGVTSFVSPEGCNTYKKPTGFTRVSAYINWINQ 264

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SPH93	NP_609840.1	GRP	<136..189	CDD:254089
		Tryp_SPc	250..485	CDD:238113	68/249 (27%)
		Tryp_SPc	252..482	CDD:214473	66/246 (27%)
cela1.2	NP_001307331.1	Tryp_SPc	29..262	CDD:214473	66/246 (27%)
cela1.2	NP_001307331.1	Tryp_SPc	30..265	CDD:238113	68/249 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910