DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SPH93 and plaua

DIOPT Version :9

Sequence 1:	NP_609840.1	Gene:	SPH93 / 35049	FlyBaseID:	FBgn0032638	Length:	494	Species:	Drosophila melanogaster
Sequence 2:	XP_017214157.1	Gene:	plaua / 100008445	ZFINID:	ZDB-GENE-090313-278	Length:	421	Species:	Danio rerio

Alignment Length:	247	Identity:	75/247 - (30%)
Similarity:	125/247 - (50%)	Gaps:	38/247 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   258 PWAVAIFHNGQYLAGGSLIQPNVVLTVAHRVIT-----IETELVVRAGDWDLKSDREIFLSEQR- 316
            ||..|||....::.||:||.|..|||.||...|     |....||...:...::|.   :.||:
Zfish   176 PWMAAIFKGDGFICGGTLITPCWVLTAAHCFPTGKRTQINRYSVVLGKNAINETDP---VKEQKF 237

  Fly   317 EVERAVIHEGFDF--KSGANNLALLFLNSPFKLND----------HIRTICLPTPNKSF-AGRRC 368
            .|.|.||||.||:  ::..:::|||      |:.|          .:||.|||...:.. .|..|
Zfish   238 TVSRLVIHEDFDYSTENYTHDIALL------KIEDCNGQCAVKTKTVRTACLPPFQQMLPVGFYC 296

  Fly   369 TVAGWGKMRYEDQRYSTVLKKVQLLVVNRNVCEKFLRSTRLGAKFELPKNIICAGG-ELGRDTCT 432
            .:||:|:.:....::|..||:.::.::::.||::...:     |.|:.:|::||.| :...|.|.
Zfish   297 EIAGYGRYQKGTFKFSRYLKQTEVKLISQKVCQRTYYN-----KDEVNENMLCANGRDWKTDACQ 356

  Fly   433 GDGGSALFCSIGGENSGVYEQAGIVNWGVGCGQEGIPAIYTEVSKFTNWITE 484
            ||.|..|.|.:    :.:....||::||..|.::..|.:||:||.:..||::
Zfish   357 GDSGGPLVCEV----NNIMFLFGIISWGKECAEKNQPGVYTQVSNYNQWISQ 404

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SPH93	NP_609840.1	GRP	<136..189	CDD:254089
		Tryp_SPc	250..485	CDD:238113	75/247 (30%)
		Tryp_SPc	252..482	CDD:214473	73/243 (30%)
plaua	XP_017214157.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910