Protein Alignment: CG12620 and PPP1R2C

• Sequence 1: NP_001260525.1
• Gene: CG12620
• FlyBaseID: FBgn0032626
• Length: 287
• Species: Drosophila melanogaster
• Sequence 2: NP_079486.1
• Gene: PPP1R2C
• HGNCID: 16324
• Length: 202
• Species: Homo sapiens
• Alignment Length: 156
• Identity: 43/157 (27%)
• Similarity: 67/157 (43%)
• Gaps: 32/157 (20%)

  Fly     8 FDKMNLGVPVHSDPY-EVENESASSIKRETGE---KVMSHKELMEKLHKEVKLTTPDFFAHDPSC 68
            :|.|....|..|  | .|::....|::...||   :.:..||..:              |.|.||
Human    63 YDLMKANEPGTS--YMSVQDNGEDSVRDVEGEDSVRGVEGKEATD--------------ASDHSC 111

  Fly    69 SSDDSEDFE-FLETI---KERARRISFVRRRKLHYTEFSTVELARRL----IREEFTESSESQLS 125
            ..|:.|..| ::..|   |:..:| .|..||:|||.|...::|||:|    ::.|..|:.|:...
Human   112 EVDEQESSEAYMRKILLHKQEKKR-QFEMRRRLHYNEELNIKLARQLMWKELQSEDNENEETPQG 175

  Fly   126 VDDEHISEIAEEECPPCG---TDSDD 148
            .::|..:....||.|..|   |.|.|
Human   176 TNEEKTAAEESEEAPLTGGLQTQSCD 201

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12620	NP_001260525.1	IPP-2	<21..111	CDD:282789	27/98 (28%)
PPP1R2C	NP_079486.1	Required for binding PPP1CC. {ECO:0000250}	12..17
		Required for binding PPP1CC. {ECO:0000250}	43..55
		IPP-2	45..170	CDD:309902	34/124 (27%)
		Required for binding PPP1CC catalytic center, displacing metal ions and inhibition of PPP1CC catalytic activity. {ECO:0000250}	144..147		2/3 (67%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C72063
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010				D1321970at2759
OrthoFinder	1	1.000				FOG0002873
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100			O	PTHR12398
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	4.040