Protein Alignment CG12620 and Ppp1r2

DIOPT Version :10

• Sequence 1: NP_609828.2
• Gene: CG12620 / 35034
• FlyBaseID: FBgn0032626
• Length: 287
• Species: Drosophila melanogaster
• Sequence 2: NP_620178.1
• Gene: Ppp1r2 / 192361
• RGDID: 621099
• Length: 205
• Species: Rattus norvegicus
• Alignment Length: 172
• Identity: 44/172 - (25%)
• Similarity: 74/172 - (43%)
• Gaps: 36/172 - (20%)

  Fly     1 MTTKRTRFDKMNLGVPVH--------------SDPYE---VENESASSIKRETGEKVMSHKELME 48
            ::.|..::|:||:....|              ..||.   .::|...|  ...|.:||:.:.|.:
  Rat    40 LSKKSQKWDEMNILATYHPADKDYGLMKIDEPDTPYHNMIGDDEDVCS--DSEGNEVMTPEILAK 102

  Fly    49 KLHKEVKLTTPDFFAHDPSCSSDDSEDFEFLETIKERARRISFVRRRKLHYTEFSTVELARRLIR 113
            || ...:.:.|.|...:...|.::..|.    :.:||.::..|..:|||||.|...::|||:||.
  Rat   103 KL-AAAEGSEPKFRTREQESSGEEDNDL----SPEEREKKRQFEMKRKLHYNEGLNIKLARQLIS 162

  Fly   114 EEFTESSESQLSVDDEHISEIAE------EECPPCGTDSDDL 149
            ::..:..|      ||.:||.|:      ||.....|..|.|
  Rat   163 KDLHDDDE------DEEMSETADADSMNIEESNQGSTAGDHL 198

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12620	NP_609828.2	IPP-2	<18..115	CDD:461504	29/113 (26%)
Ppp1r2	NP_620178.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..44		0/3 (0%)
		Required for binding PPP1CC. /evidence=ECO:0000250	12..17
		Required for binding PPP1CC. /evidence=ECO:0000250	43..55		4/11 (36%)
		IPP-2	45..164	CDD:461504	32/125 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	104..142		8/42 (19%)
		Required for binding PPP1CC catalytic center, displacing metal ions and inhibition of PPP1CC catalytic activity. /evidence=ECO:0000250	147..150		2/2 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	163..205		11/42 (26%)