Protein Alignment Cse1 and kap109

DIOPT Version :10

• Sequence 1: NP_523588.2
• Gene: Cse1 / 35016
• FlyBaseID: FBgn0022213
• Length: 975
• Species: Drosophila melanogaster
• Sequence 2: NP_595530.1
• Gene: kap109 / 2540419
• PomBaseID: SPBC30B4.05
• Length: 967
• Species: Schizosaccharomyces pombe
• Alignment Length: 975
• Identity: 346/975 - (35%)
• Similarity: 552/975 - (56%)
• Gaps: 42/975 - (4%)

  Fly    15 LQQTLSADPNVRRPAEKLLESTELQ-QNYPILLLNLIDKAQMDMTTRVAGAIAFKNYIKRNWAAH 78
            |.:||  :|...:.||:.|:..||| .::.:.|||::.:..:|:..::|.::.||||||::|
pombe     8 LARTL--NPTTSKSAEEALKVWELQDSSFALKLLNIVAEDTVDINIKLAASLYFKNYIKKHW--- 67

  Fly    79 LDSDGPDRIHESDR--NTIKTLIVTLMLHSPVALQKQLSDAVSIIGKYDFPKKWPQLIDEMVERF 141
             ||:....|..||.  ..||..|:.|||.|...:|.||.:.:..|..:|||.:|..|:.:::.:.
pombe    68 -DSEEGASIRISDEVAELIKREIINLMLKSTTIIQVQLGEVIGYIANFDFPDRWDTLLPDLISKL 131

  Fly   142 ASGDFNVINGVLQTAHSLFKRYRYEFKSQALWEEIKFVLDRMAKPLTDLLQATMQLTKVHENNAG 206
            ::.|.|....||.|||::|||:|..|:|.||:.|||:||||..:|...|...|..|.:....:|.
pombe   132 SAVDMNTNIAVLSTAHAIFKRWRPLFRSDALFLEIKYVLDRFCEPFLALFVQTNNLLRNGPQDAE 196

  Fly   207 ALKVIYGSLVLVNKVFFSLNSQDLPEFFEDNINTWMGAFIQQLAADVPSLRTADDEDAGVLEHLR 271
            :|..::..::|..|:|:.||.||:||||||:::.:|.||:.......|||. .|:.:..||..::
pombe   197 SLNSLFQVILLECKLFYDLNCQDIPEFFEDHMSEFMTAFLNYFTYTNPSLE-GDEGETNVLIKVK 260

  Fly   272 AQVCENICLYAKKYDEEFKPFMEQFVTAVWELLVKTSLHTKYDSLVSHALQFL-SVVADRQHYQS 335
            |.:||.:.||..:|:|.| ..:..||...|.||...:...|||.||..|:.|| ||:..|:|.:
pombe   261 ASICEIVELYTLRYEEVF-TMLYDFVNVTWTLLTTLTPDEKYDGLVGKAMAFLTSVIRIRKHAE- 323

  Fly   336 IFENPEILAQICDKVVIPNLDIRPSDEEIFEDSPEEYIRRDIEGSDIDTRRRAACDLVKTLSINF 400
            .|:..::|.|..:.||:||:.:|.||||:|||.|.||:|||:|||:.|:|.|:|..||:.|..:|
pombe   324 FFQQDQVLQQFIELVVLPNICLRESDEELFEDDPLEYVRRDLEGSNSDSRARSAIVLVRGLLDHF 388

  Fly   401 EQKIFGIFGQYLERLLTKYKENPATNWRSKDTAIYLVTSWASRGGTQKHGITQTSELVPLPEFCA 465
            :|||..:...::...|.::..||:..|..|..|:.|.::.|.:|.:.:.|:|..:.:|.:..|..
pombe   389 DQKITSVVSTHINANLQQFSTNPSLEWNKKYVALQLFSAIAIKGQSTRLGVTSINLMVDVVAFFE 453

  Fly   466 QQIIPELERPNINEFPVLKAAAIKYVMVFRSILGPQVLASCLPQLIRHLPAESSVVHSYAACSVE 530
            ..|.|:|.:|.....|::.|..||||..||:.|..|.|....|.::|.|...|.||::|||.:::
pombe   454 NNIKPDLLQPAGVIHPMVLAEDIKYVFTFRNQLNSQQLIDIFPTILRFLEMPSFVVYTYAAIALD 518

  Fly   531 KILSMRDASNAIVFGPQILAPYTTELISGLF---ATLSLPGS-GENEYVMKAIMRSFSVLQSAAM 591
            ::|::|. ::..:|...::||:....::.||   .:.|.|.. .||:|:|||:||...:.|.|.:
pombe   519 QLLTVRH-NHVHIFTSLLIAPHILPALNQLFLIVESASTPQKLAENDYLMKAVMRIIIMSQEAIL 582

  Fly   592 PFMGVALPRLTEILTQVAKNPSRPQFNHYLFETLALCIKIVCHADSSAVSSFEEALFPVFQGILQ 656
            |...:.|..||:|..:|:||||.|:|||||||::...|:.:..:....||..|.||.||||.:|.
pombe   583 PAASLLLQHLTKITEEVSKNPSNPKFNHYLFESIGALIRSLSKSGPQTVSQLENALLPVFQNVLI 647

  Fly   657 QDIVEFMPYVFQMLSVLLEMREGTGTIPEPYWA---LFPCLLSPALWDRTGNVTPLIRLISAFIK 718
            :|:.||:|||.|:||.|:   |.:|..|.|.:.   :.|| |||||||..||:..|:||:.|.|.
pombe   648 EDVTEFIPYVLQLLSQLV---EASGNEPLPDFVVNLIQPC-LSPALWDSKGNIPALVRLLRAMIF 708

  Fly   719 QGSAQIQALGK-LSGILGIFQKMIASKANDHEGFYLLQNLLSYYPPAEIQTNLRQIFGLLFQRLS 782
            :| .||....| :..:||||||:|:||.|||.||.||..:.:.:....:...:..||.||..||.
pombe   709 RG-PQIFISNKFVEPVLGIFQKLISSKVNDHFGFDLLDRVFTVFNANILAPYINHIFFLLLSRLK 772

  Fly   783 LSKTPKYLSGIIIFFSFYVIKFSGS----QMAQLIDEIQPNLFGMLLDRVFITEMGKIPKEQDRK 843
            .|:|.:::....|||.|...:.:|:    .:.|.:|.:|..:||.|:..:.:.:..|:....|||
pombe   773 NSRTERFVLRCTIFFFFVASEQTGTCGPDNLIQGVDAVQSGVFGQLMTSIILPQAQKLALPLDRK 837

  Fly   844 MVAVGVTKLLT----ETPEILQQQYATFWPRLLHSLIDLFERPPEKLMGLEIGETAGVAE-DPDA 903
            :.|:|:.:|||    ..|:.:   |......||..::.|||.|.|:.. .:..|...:.| |.|:
pombe   838 ISALGLLRLLTCDLVLAPDAI---YENLIIPLLTCILKLFEMPIEQAQ-TDADEELFMDEIDADS 898

  Fly   904 -GYQVAFAQLTHAQPNQQDHLAEIKDARQFLATSLSKFAQARAGEFSTLLSP-LEPEYKQVLQKY 966
             .:|.:|::|......:.|...:|.|.:|:.||.::...:...|..|.::|. |..:.:.|||.|
pombe   899 MSFQASFSRLATTGGKRVDPFPQITDLKQYCATEMNLANRNMGGRLSQIISTHLPGDGQSVLQSY 963

  Fly   967  966
            pombe   964  963

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cse1	NP_523588.2	IBN_N	29..105	CDD:397745	28/78 (36%)
		Cse1	159..529	CDD:430038	140/370 (38%)
		CAS_CSE1	530..966	CDD:367469	155/454 (34%)
kap109	NP_595530.1	CSE1	1..967	CDD:227944	346/975 (35%)