DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ChLD3 and Cda5

DIOPT Version :9

Sequence 1:	NP_609806.1	Gene:	ChLD3 / 35002	FlyBaseID:	FBgn0032598	Length:	577	Species:	Drosophila melanogaster
Sequence 2:	NP_722590.2	Gene:	Cda5 / 33158	FlyBaseID:	FBgn0051973	Length:	1998	Species:	Drosophila melanogaster

Alignment Length:	364	Identity:	159/364 - (43%)
Similarity:	221/364 - (60%)	Gaps:	24/364 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   211 AGACDPRKCHLPQCFCSKDGTQIPGSLPAQSVPQMILLTFDDAINHDNWELFSKVLFTQHRRNPN 275
            |..|....|.||.|:|.  |..|||.||.:|:||::||||||::|..|.:|::. ||.:.|.|||
  Fly  1634 AAKCRKDVCLLPDCYCG--GRDIPGELPVESIPQIVLLTFDDSVNDLNKQLYTD-LFEKGRVNPN 1695

  Fly   276 GCPIKGTFYVSHPFTNYQYVQKLWNDGHEIAVHSVTHRGPEMWWSKNATIEDWFDEMVGQANIIN 340
            ||||..||||||.:|:|..||.|:.||||:|.|:|:|...|.:..|.     |..|:.||..|:.
  Fly  1696 GCPITATFYVSHEWTDYSQVQNLYADGHEMASHTVSHSFGEQFSQKK-----WTREIAGQREILA 1755

  Fly   341 KFAAVRMEEIRGMRVPFLRVGWNRQFLMMKEFGFVYDSSMVAPHSNPPLWPYTLDYKMPHSCTGV 405
            .:..|:|.::||||.|||.||.|:.:.|:.:..|.|||||....:.||.||||||||:.|.|  :
  Fly  1756 AYGGVKMSDVRGMRAPFLSVGGNKMYKMLYDSNFTYDSSMPVYENRPPSWPYTLDYKIFHDC--M 1818

  Fly   406 NQNCPSRSYPGIWELVM---NQLEVGEYMCGMVDTCPPHLSGEDVYRMLTHNFKRHYLSNRAPFG 467
            ...||:|||||:|::.|   ..|..|.  |.|.|.|......:.|.:|:..||:|||.:||||||
  Fly  1819 IPPCPTRSYPGVWQVPMVMWQDLNGGR--CSMGDACSNPSDADGVTKMIMKNFERHYTTNRAPFG 1881

  Fly   468 LYFHSTWFKKVDYLNAFLKFLDDLQKLPDVFFVTNQQAIQWMRHPTPSNQLHQFESWHCQPKDLD 532
            |::|:.||.:..:...|:||||.:..:.||:.:||.||:||:|.|||.::::.|:.:.|   |..
  Fly  1882 LFYHAAWFTQPHHKEGFIKFLDAINAMQDVWIITNWQALQWVRDPTPISRINSFQPFQC---DYS 1943

  Fly   533 PHEQVCNTPNVCKV--RSRVLQEDRFFYTCMECPAQYPW 569
            ...:.||.|.||.:  :|.|    |:..||..||..|||
  Fly  1944 DRPKRCNNPKVCNLWHKSGV----RYMKTCQPCPDIYPW 1978

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ChLD3	NP_609806.1	CBM_14	<111..149	CDD:279884
		LDLa	168..202	CDD:238060
		CE4_CDA_like_1	243..512	CDD:200596	124/271 (46%)
Cda5	NP_722590.2	CBM_14	58..106	CDD:279884
Cda5	NP_722590.2	CE4_CDA_like_2	1664..1926	CDD:200597	124/271 (46%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	94	1.000	Domainoid score	I4700
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1060206at2759
OrthoFinder	1	1.000	-	-		FOG0003270
OrthoInspector	1	1.000	-	-		otm14253
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR45985
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	6.020