DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5888 and lrrc38a

DIOPT Version :9

Sequence 1:	NP_001285981.1	Gene:	CG5888 / 34980	FlyBaseID:	FBgn0028523	Length:	455	Species:	Drosophila melanogaster
Sequence 2:	XP_021325623.1	Gene:	lrrc38a / 567935	ZFINID:	ZDB-GENE-080327-12	Length:	290	Species:	Danio rerio

Alignment Length:	112	Identity:	26/112 - (23%)
Similarity:	56/112 - (50%)	Gaps:	4/112 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly   256 VPTELFWMSEQLAYIGIRSN-ISYLSKDFLKVQKKLLTLRLERNNIARLPDQLFRNTPLILEIHL 319
            :|::...:...|.|:.:|:| ::.|....|....:|:.|.|..||:..:|...|..:..::::.|
Zfish    69 IPSDFLVLYSDLVYLDLRNNSLTRLEPGTLSTSSRLVYLDLGSNNLTEIPSGTFGESRSLIKLRL 133

  Fly   320 AFNN--LDRIQSGLFDKLKNLQVLNLEHNPITTIALNAFTPIPTAHI 364
            . ||  |:.:....|..|.:|:.|.||.|.::.:.:...:.:|:..:
Zfish   134 G-NNPYLNMVSKDAFLGLTSLRELELESNALSGLDVEVLSQLPSLRV 179

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5888	NP_001285981.1	leucine-rich repeat	168..189	CDD:275380
		leucine-rich repeat	190..213	CDD:275380
		leucine-rich repeat	214..243	CDD:275380
		leucine-rich repeat	244..266	CDD:275380	1/9 (11%)
		leucine-rich repeat	267..289	CDD:275380	6/22 (27%)
		LRR_8	288..348	CDD:290566	18/61 (30%)
		leucine-rich repeat	290..313	CDD:275380	7/22 (32%)
		leucine-rich repeat	314..337	CDD:275380	6/24 (25%)
		leucine-rich repeat	338..357	CDD:275380	5/18 (28%)
lrrc38a	XP_021325623.1	LRRNT	26..56	CDD:214470
		leucine-rich repeat	36..58	CDD:275380
		leucine-rich repeat	59..79	CDD:275380	1/9 (11%)
		PLN00113	<60..>185	CDD:331614	26/112 (23%)
		leucine-rich repeat	80..103	CDD:275380	6/22 (27%)
		LRR_8	102..163	CDD:316378	18/61 (30%)
		leucine-rich repeat	104..127	CDD:275380	7/22 (32%)
		leucine-rich repeat	128..152	CDD:275380	6/24 (25%)
		leucine-rich repeat	153..176	CDD:275380	5/22 (23%)
		TPKR_C2	185..>219	CDD:326558
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR46473
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.100