Protein Alignment CG5888 and lron-12

DIOPT Version :10

• Sequence 1: NP_609794.1
• Gene: CG5888 / 34980
• FlyBaseID: FBgn0028523
• Length: 455
• Species: Drosophila melanogaster
• Sequence 2: NP_001366666.1
• Gene: lron-12 / 190700
• WormBaseID: WBGene00013542
• Length: 398
• Species: Caenorhabditis elegans
• Alignment Length: 368
• Identity: 65/368 - (17%)
• Similarity: 132/368 - (35%)
• Gaps: 126/368 - (34%)

  Fly     1 MWWLLLLLSLIAPSWQENATVINPSYVTKAGCEALVKEPNLCECQE--QEIKCENLQLHSDNLQL 63
            :|.||:|...:..|   ||        .:..|      |..|:|.|  |::.||..|:
 Worm    14 IWKLLILFHFLKYS---NA--------LRDTC------PMGCQCDEDKQQVTCEGQQV------- 54

  Fly    64 YGISCSIFDARGFGYIPPLKVGNIGSLIVQNCAIPNAESIKYLLSKLGVSNYTELEIFNYFDPKK 128
                .::.|....||         .||:::|.::...|.          :::.::|
 Worm    55 ----VTLPDRLPSGY---------ESLVIRNSSVRTIEK----------NSFRKME--------- 87

  Fly   129 TDRGEVLQQHYTDHESLKKVSIIGFKSTLPENFLENLPALQQLSLKGSSDLPGNILHPLKNLTHL 193
                :::|..:.::.:|..:..:.||.      |:.:..::..:..|.::|..|....::|...|
 Worm    88 ----KLMQIEFENNPNLGTIEKLAFKG------LKKIRLIKFTTCPGLTELQKNAFSGIQNQMGL 142

  Fly   194 EIVVKN--LGKVSGAIFAKQSKLKHLMIDCDAKNSSVEMSAFGPQELWHMTELQSIELFNCGDNV 256
            :|:.:.  :.::.|..|.....::.|.|      |..|::.             |...|
 Worm   143 KIIFEKTPIHRIDGHTFRNAQNIRELTI------SGEELAL-------------SRHCF------ 182

  Fly   257 PTELFWMSEQLAYIGIRSNISYLSKDFLKVQKKLLTLRLERNNIARLPDQLFRNTPLILEIHLAF 321
                             :||:.|  |||.|           :.:..:..::|.|:.....:|...
 Worm   183 -----------------ANINQL--DFLTV-----------SGVVLIEPEIFTNSTRFHVVHFKN 217

  Fly   322 NNLDRIQSGLFDKLKNLQVLNLEHNPITTIALNAFTPIPTAHI 364
            :..| |....|..|.:...|.:||:.:.:||.:||:.:.|..:
 Worm   218 SQFD-IPPSTFSTLSHTSHLLIEHSKVPSIAPDAFSGLTTIQV 259

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5888	NP_609794.1	LRR	<160..>359	CDD:443914	36/200 (18%)
		leucine-rich repeat	168..189	CDD:275380	3/20 (15%)
		leucine-rich repeat	190..213	CDD:275380	4/24 (17%)
		leucine-rich repeat	214..243	CDD:275380	4/28 (14%)
		leucine-rich repeat	244..266	CDD:275380	2/21 (10%)
		leucine-rich repeat	267..289	CDD:275380	7/21 (33%)
		leucine-rich repeat	290..313	CDD:275380	2/22 (9%)
		leucine-rich repeat	314..337	CDD:275380	5/22 (23%)
		leucine-rich repeat	338..357	CDD:275380	6/18 (33%)
lron-12	NP_001366666.1	leucine-rich repeat	45..67	CDD:275380	7/41 (17%)
		LRR_5	66..184	CDD:463839	24/188 (13%)
		leucine-rich repeat	68..88	CDD:275380	4/42 (10%)
		leucine-rich repeat	89..113	CDD:275380	5/29 (17%)
		leucine-rich repeat	114..138	CDD:275380	3/23 (13%)
		leucine-rich repeat	139..164	CDD:275380	4/24 (17%)
		LRR	<159..>294	CDD:443914	29/157 (18%)
		leucine-rich repeat	165..187	CDD:275380	8/63 (13%)
		leucine-rich repeat	188..209	CDD:275380	7/33 (21%)
		leucine-rich repeat	210..232	CDD:275380	5/22 (23%)
		leucine-rich repeat	233..256	CDD:275380	7/22 (32%)
		leucine-rich repeat	257..277	CDD:275380	0/3 (0%)