Protein Alignment CG4278 and Nif3l1

DIOPT Version :10

• Sequence 1: NP_609790.1
• Gene: CG4278 / 34970
• FlyBaseID: FBgn0014092
• Length: 292
• Species: Drosophila melanogaster
• Sequence 2: NP_075364.2
• Gene: Nif3l1 / 65102
• MGIID: 1929485
• Length: 376
• Species: Mus musculus
• Alignment Length: 349
• Identity: 120/349 - (34%)
• Similarity: 173/349 - (49%)
• Gaps: 90/349 - (25%)

  Fly    13 LAAVVKELENFAPTSWAEKWDNVGLLIEPHREKQIKKILLTNDLTEPVVKEALEKEAELIISYHP 77
            |.|::..|.:||..|:||.|||||||:||.....:..:.|||||||.|:.|||:|:|:.|:||||
Mouse    29 LKALLSSLNDFASLSFAESWDNVGLLVEPSPPHTVNTLFLTNDLTEEVMDEALQKKADFILSYHP 93

  Fly    78 PIFKPLTRITQSHWKERVVAACLANDIALYSPHTAWDKKSGGVNDWLSKAVNIISIRPLEPELGA 142
            |||:|:..||...|||.:|...|.|.:|:||||||:|....|||.||:|.:...:.||:.|. .|
Mouse    94 PIFRPMKHITWKTWKECLVIRALENRVAVYSPHTAYDAAPQGVNSWLAKGLGTCTTRPIHPS-RA 157

  Fly   143 P--------------------------------------PG------------------------ 145
            |                                      |.
Mouse   158 PDYPTEGAHRLEFSVNRSQDLDKVMSTLRGVGGVSVTSFPARCDGEEQTRISLNCTQKTLMQVLA 222

  Fly   146 ------------------------TGSGRY--IETKMELSQVVESLQKRIRNS-VHVALAVGHTP 183
                                    ||.||.  ::..:.|:.::|.::..::.| :.:||.||.|.
Mouse   223 FLSQDRQLYQKTEILSLEKPLLLHTGMGRLCTLDESVSLAIMIERIKTHLKLSHLRLALGVGRTL 287

  Fly   184 KTLIQSVGICAGSGASLLKGIQADLIITGEMSHHEVLEFTHNNTTVLLCNHSNSERGFLHEFCPI 248
            ::.::.|.:|||||.|:|:|::|||.:|||||||:||:.......|:||.|||:|||||.|...:
Mouse   288 ESQVKVVALCAGSGGSVLQGVEADLYLTGEMSHHDVLDAASKGINVILCEHSNTERGFLSELQEM 352

  Fly   249 LAKSLNEECLVFVSEVDKDPLVTV 272
            |......:..:.:||.|:|||..|
Mouse   353 LGVHFENKINIILSETDRDPLRVV 376

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4278	NP_609790.1	NIF3	16..251	CDD:426431	111/323 (34%)
Nif3l1	NP_075364.2	NIF3	32..353	CDD:426431	110/321 (34%)
		Mediates interaction with COPS2. /evidence=ECO:0000269|PubMed:12522100	243..376		52/132 (39%)