Protein Alignment cact and Nfkbie

DIOPT Version :10

• Sequence 1: NP_476942.1
• Gene: cact / 34969
• FlyBaseID: FBgn0000250
• Length: 500
• Species: Drosophila melanogaster
• Sequence 2: NP_001291885.1
• Gene: Nfkbie / 18037
• MGIID: 1194908
• Length: 371
• Species: Mus musculus
• Alignment Length: 414
• Identity: 114/414 - (27%)
• Similarity: 169/414 - (40%)
• Gaps: 85/414 - (20%)

  Fly    68 PNETSDSGFISGPQSSQIFSEEIVPDSEEQDKDQQESAPQ--KEQPVVLDSGIIDEEEDQEEQEK 130
            |:|..||...||.:|.:.......|.:.......|...||  :..|               |..|
Mouse     8 PDEADDSQCDSGIESLRSLRSLPEPTAAPGSGSSQSGCPQPWRHAP---------------ETHK 57

  Fly   131 EEEHQDTTTATADSMRLKHSADTGIPQWTVESHLVSRGEQLNNLGQSSSTQITGRSKVQSSTAST 195
            |.|.:|.....|||.....|.....|       |:.|.|.
Mouse    58 EPEKEDADGERADSTYASSSLTESFP-------LLERPEA------------------------- 90

  Fly   196 ANANPSGSGATSSAPPSSINIMNAWEQFYQQNDDGDTPLHLACISGSVDVVAALIRMAPHPCLLN 260
              .:||.....|..||:.:......|.....::||||.||||.|..:..|:...:...|.. :|:
Mouse    91 --KDPSPPAPGSPLPPAGVLSPQQLEALTYISEDGDTLLHLAVIHEAPSVLFCCLAFLPQE-VLD 152

  Fly   261 IQNDVAQTPLHLAALTAQPNIMRILLLAGAEPTVRDRHGNTALHLSCIAGEKQCVRALTEKFGAT 325
            |||::.||.||||....||:::|.|:|.||...::|:||:||||::|......|...|.|
Mouse   153 IQNNLYQTALHLAVHLDQPDVVRALVLKGASRILQDQHGDTALHVACRRQNLACACCLLE----- 212

  Fly   326 EIHEAHRQYGHRSNDKAVSSLSYACLPADLEIRNYDGERCVHLAAEAGHIDILRILVSHGADINA 390
            |..|..||..|               |.||:::|:.|..|:|:|....:..::.:|:.:||||:.
Mouse   213 EQPEPGRQLSH---------------PLDLQLKNWQGLACLHIATLQRNQPLIELLLQNGADIDV 262

  Fly   391 REGKSGRTPLHIAIEGCNEDLANFLLD-----ECEKLNLETATYAGLTAYQFACIMNKSRMQNIL 450
            :||.||:|.||:|:|.....|..|||.     :...||       |.|....|.....:.:.:.|
Mouse   263 QEGTSGKTALHLAVETQERSLVQFLLQAGARVDARMLN-------GCTPLHLAAGRGLNSISSTL 320

  Fly   451 EKRGAETVTPPDSDYDSSDI-EDL 473
            .:.||:::.....|....|: |||
Mouse   321 CEAGADSLLLNVEDETPQDLAEDL 344

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cact	NP_476942.1	ANKYR	<225..464	CDD:440430	78/243 (32%)
		ANK repeat	229..263	CDD:293786	13/33 (39%)
		ANK repeat	265..296	CDD:293786	13/30 (43%)
		ANK repeat	298..324	CDD:293786	10/25 (40%)
		ANK repeat	361..393	CDD:293786	9/31 (29%)
		ANK repeat	395..425	CDD:293786	13/34 (38%)
Nfkbie	NP_001291885.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..108		30/148 (20%)
		ANKYR	121..345	CDD:440430	83/252 (33%)
		ANK repeat	122..155	CDD:293786	13/33 (39%)
		ANK 1	122..155		13/33 (39%)
		ANK 2	157..186		13/28 (46%)
		ANK repeat	159..188	CDD:293786	13/28 (46%)
		ANK repeat	190..231	CDD:293786	18/60 (30%)
		ANK 3	190..219		12/33 (36%)
		ANK 4	233..262		9/28 (32%)
		ANK repeat	234..264	CDD:293786	9/29 (31%)
		ANK repeat	267..298	CDD:293786	11/30 (37%)
		ANK 5	267..296		11/28 (39%)
		ANK repeat	300..334	CDD:293786	7/40 (18%)
		ANK 6	300..329		7/35 (20%)