DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5861 and ZK418.5

DIOPT Version :9

Sequence 1:	NP_609789.1	Gene:	CG5861 / 34965	FlyBaseID:	FBgn0015338	Length:	227	Species:	Drosophila melanogaster
Sequence 2:	NP_498544.1	Gene:	ZK418.5 / 175987	WormBaseID:	WBGene00022734	Length:	225	Species:	Caenorhabditis elegans

Alignment Length:	222	Identity:	84/222 - (37%)
Similarity:	128/222 - (57%)	Gaps:	11/222 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MTLYHFGNCVAL-LTPYYFTYKYSGLSEYGAFWKCVQAGGIYIFTQLVKMLVLATFFYSDAPSSS 64
            |:.:||.||.|| ..||:..|||||::||.:.|||..|.|.|:.|||.|:|::||||    |:..
Worm     1 MSFFHFINCFALAFAPYFIVYKYSGINEYSSIWKCATASGGYLLTQLAKLLIIATFF----PALD 61

  Fly    65 GE-FNFFAEILRCSMDIADLLGFALILSR-IPGKGHSKLITAGLGWATAEVILSRGIMLWVGARG 127
            .| |:...|.|:.|.||.|::|..|:::. :.|||..:.:..||||..|..:..|.::|||||||
Worm    62 SEGFSIVPEFLKSSADIIDVIGLHLLMTNFLAGKGEVRFVVGGLGWGFAHSVAHRLVLLWVGARG 126

  Fly   128 TEFSWIYILKCLESNVLLVQHITTATLIWLFTRHDLNKALKPLVSLLLAVTVFKGVWLEGMLHIL 192
            |.|:|.::...|:|:..|:..::.|.|.|:.||.. ||.   |||.:||:.||.....:.:.|..
Worm   127 TAFTWRWVQTSLDSSADLLVIVSLACLTWMITRTP-NKF---LVSPILAMCVFSTFVYQTVQHTF 187

  Fly   193 TIGPWLTVAVKALVAAVIGFCTLHIYS 219
            ::..|..:|.:...:......|:.:||
Worm   188 SLYGWSLLAFRFAYSIATAILTVVVYS 214

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5861	NP_609789.1	DUF2053	2..157	CDD:401642	65/157 (41%)
ZK418.5	NP_498544.1	DUF2053	2..159	CDD:286808	66/160 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160158427
Domainoid	1	1.000	140	1.000	Domainoid score	I2964
eggNOG	1	0.900	-	-		E1_KOG3236
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H12330
Inparanoid	1	1.050	155	1.000	Inparanoid score	I2924
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54820
OrthoDB	1	1.010	-	-		D1388283at2759
OrthoFinder	1	1.000	-	-		FOG0006016
OrthoInspector	1	1.000	-	-		oto19232
orthoMCL	1	0.900	-	-		OOG6_105654
Panther	1	1.100	-	-	LDO	PTHR12869
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3948
SonicParanoid	1	1.000	-	-		X4313
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	16	15.800