Protein Alignment twe and cdc-25.1

DIOPT Version :10

• Sequence 1: NP_476633.1
• Gene: twe / 34954
• FlyBaseID: FBgn0002673
• Length: 426
• Species: Drosophila melanogaster
• Sequence 2: NP_491862.1
• Gene: cdc-25.1 / 172353
• WormBaseID: WBGene00000386
• Length: 604
• Species: Caenorhabditis elegans
• Alignment Length: 401
• Identity: 107/401 - (26%)
• Similarity: 164/401 - (40%)
• Gaps: 93/401 - (23%)

  Fly    14 DDESGACGQENFDPHDAD-MEYQAKRRKSAVQETPLQWMLKRHIPASTTVLSPITELSQNMNGAR 77
            |..:|...:..||....| .||:    |..:.|.|..    .|...:::.:||...|........
 Worm   105 DTPTGRKMKTVFDLDSLDHSEYE----KRVMSERPTD----NHRKRTSSSMSPSVTLLDRKRSRN 161

  Fly    78 LD-GTPKSTQRIPANRTLNNFNSLSSRTLGSFSSSCSSYESGNSLDDEYMDMFEMESAENHNLEL 141
            |. ..|:|                        ..||......|..||.:.|
 Worm   162 LSLVAPQS------------------------DKSCRYNGLNNPRDDPFGD-------------- 188

  Fly   142 PDDLEVLLSGQLKSESNLEEMSNKKGSLRRCLSMYPSEQPEEAVQEPDQETNMPMKKMQRKT--L 204
             :|.||.            |.||.:.|..:..|::....|..|....|.   .|....:|||  .
 Worm   189 -EDDEVF------------EQSNVRNSQVQNTSIFAQPAPRTATSLWDL---APPMFFERKTSDT 237

  Fly   205 SMNDA------EIMRAL--GD-EPELIGDLSKPCTLPCLATGIRH-RDLKTISSDTLARLIQ--- 256
            |.|.:      :|:||:  |: :.||...|....|||.:....|. :..::||..||....|
 Worm   238 SGNGSFQERPKQILRAMSVGEIDSELPPTLEVKYTLPGVDNPQRESQAFRSISPTTLLLEFQRLG 302

  Fly   257 GEFDEQLGSQGGYEIIDCRYPYEFLGGHIRGAKNLYTRGQIQEAFPTLTSNQE----NRRIYVFH 317
            .:||::      |.|:|||:|:|:.|||::||.||:...:|:..|  ...|.|    ..|:.:|:
 Worm   303 DDFDKK------YIIVDCRFPFEYKGGHVKGAINLFRHDKIKPIF--FPENGEASSFQNRVPIFY 359

  Fly   318 CEFSSERGPKLLRYLRSNDRSQHTHNYPALDYPELYILHNGYKEFFGLYS--QLCQPSQYVPMLA 380
            ||:|.:|||.:...:||.||..:...||.::|||:|:|..|||..:....  |:|:|..|:||..
 Worm   360 CEYSQKRGPTMAHAVRSIDRVLNELRYPHVEYPEMYLLDYGYKSLWSTAECRQICEPCSYIPMTH 424

  Fly   381 PAHNDEFRYFR 391
            .:.:.||:..|
 Worm   425 SSFSMEFKSAR 435

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
twe	NP_476633.1	Cdc25	243..363	CDD:238788	47/126 (37%)
cdc-25.1	NP_491862.1	Cdc25	286..406	CDD:238788	47/127 (37%)