Protein Alignment twe and cdc25b

DIOPT Version :10

• Sequence 1: NP_476633.1
• Gene: twe / 34954
• FlyBaseID: FBgn0002673
• Length: 426
• Species: Drosophila melanogaster
• Sequence 2: XP_002936339.2
• Gene: cdc25b / 100036608
• XenbaseID: XB-GENE-1012329
• Length: 560
• Species: Xenopus tropicalis
• Alignment Length: 506
• Identity: 136/506 - (26%)
• Similarity: 227/506 - (44%)
• Gaps: 133/506 - (26%)

  Fly    13 EDDESGACGQENFDPHDADMEYQAKRR---KSAVQETPLQWMLKR--HIPASTTVLSP-ITELSQ 71
            :..:||.| .::..|.|:::.::...:   :|.:....::..::|  .:|.:....|| :..||.
 Frog    89 DSSDSGLC-LDSPSPQDSELPHETFEKVIFESRIPPNDIKLPIRRIHSLPETLQGGSPALRRLSH 152

  Fly    72 NMNGARLDGTPKSTQRIPANR-------------------TLNNFNSLSSR-----------TLG 106
            .::   || .||..::|||.:                   .|..|:..|.|           ||.
 Frog   153 PLD---LD-LPKPLEKIPAEKDNKENELLLFKKPRPFLRTRLRTFDGCSDREAFSERPNSAPTLM 213

  Fly   107 SFSSSCSSYESGN-------------SL------DDEYMDMFEMESAENHNLELPDDLEVLLSGQ 152
            .||....:.|..|             ||      ||.:|::.:.|..:.   ::|..:..||:..
 Frog   214 FFSPDKINSEMENESPIRLRKSSLTFSLCNDDDDDDGFMEIMDDEEIKT---DIPSGMRNLLTAP 275

  Fly   153 LKSESNLEEMSNKKGSLR-RCLSMYPSEQPEEAVQEP---------DQETNMPMKKMQRKTLSMN 207
            .   .|.|:.|:....:: :|..::.|.....::..|         |.||  |:|..:.|.|..:
 Frog   276 F---VNKEDKSDPDLIIKSKCRRLFRSPSMPSSIIRPILKRLDRPEDGET--PVKSKRLKNLPQS 335

  Fly   208 DAE----------------------IMRAL-GDEPELIGDLSKPCTLPCLATGIRHRDLKTISSD 249
            .:|                      :.:.| .||.|||||.||...|..:..  :|:|||.|:.:
 Frog   336 HSEEWPENEEPKMKLGRSKSVCLATVEKILDNDERELIGDSSKAYLLKTVEG--KHQDLKYITPE 398

  Fly   250 TLARLIQGEFDEQLGSQGGYEIIDCRYPYEFLGGHIRGAKNLYTRGQIQEAF----PTLTSNQEN 310
            .:..::.|::.:.:..   ..|||||||||:.||||:||.||.....: ||:    |.:..:.:.
 Frog   399 MMDCVLSGKYKDTIER---CVIIDCRYPYEYEGGHIKGAINLPLEQDV-EAYLLKEPIVPQSPDK 459

  Fly   311 RRIYVFHCEFSSERGPKLLRYLRSNDRSQHTHNYPALDYPELYILHNGYKEFFGLYSQLCQPSQY 375
            |.|.:|||||||||||::.|::|..||  :::.||.|.|||||:|..|||:||..:...|:|..|
 Frog   460 RVIIIFHCEFSSERGPRMCRFIRKQDR--NSNEYPKLHYPELYVLKGGYKDFFPSFQSQCEPQSY 522

  Fly   376 VPMLAPAHNDEF----RYFRAKTKSWQCGEGGDSGIGGGGSRGLRKSRSRL 422
            .||    |:::|    :.||:|:::|            .|.:..|:..|||
 Frog   523 RPM----HHEDFKEHLKLFRSKSRTW------------AGDKSKREMYSRL 557

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
twe	NP_476633.1	Cdc25	243..363	CDD:238788	53/123 (43%)
cdc25b	XP_002936339.2	M-inducer_phosp	97..363	CDD:461962	49/277 (18%)
		Cdc25	392..511	CDD:238788	54/124 (44%)