Protein Alignment BicC and YLL032C

DIOPT Version :10

• Sequence 1: NP_476865.1
• Gene: BicC / 34946
• FlyBaseID: FBgn0000182
• Length: 905
• Species: Drosophila melanogaster
• Sequence 2: NP_013068.1
• Gene: YLL032C / 850627
• SGDID: S000003955
• Length: 825
• Species: Saccharomyces cerevisiae
• Alignment Length: 749
• Identity: 141/749 - (18%)
• Similarity: 238/749 - (31%)
• Gaps: 267/749 - (35%)

  Fly     6 SFNKLMY-PS----AADVAKPPMVGLEVEAGSIGSLSSLHALPSTTSVGSGAPSETQSEISSVDS 65
            :|...:| ||    :.|:...|.:..   :|::.|||.|.......|:...:.|.....::::
Yeast   214 AFKTSIYAPSLITLSRDLKANPQIFF---SGAVHSLSLLARKTLRESISVNSKSFFYRRLTNI-- 273

  Fly    66 DWSDIRAIAMKLGVQNPDDLHTERFKVDRQKLEQLI-KAESSIEGMNGAEYF------------- 116
                           .|..|...| |..:||:.||| |.:|.|...|  ||.
Yeast   274 ---------------TPGKLLFIR-KYYQQKVNQLILKYQSLIRVTN--EYIEFQSISTNLLEMV 320

  Fly   117 --------FHDIMNT---------------TDTYVSWPCRLKIGAKSKKDP--HVRIVGKVDQVQ 156
                    .|:|:..               .|::........:....|:|.  .:.:||......
Yeast   321 IKNFTIQVLHEIVEVQISLNENCAMSPELIIDSFFGHTGNQIVVITPKEDSFNQLIVVGNQSSTD 385

  Fly   157 RAKE-RILSSLDS-------------RGTRVIMKMDVSYTDHSYIIGRGGNNIKRIM-------- 199
            .|.: .||..|..             |..:.|.::...:.|  :|.|:....:.|||
Yeast   386 EASDTSILHYLSDFIMGSNQVINPNLRQIKAIFEIHPDFED--FISGKKNGKLTRIMELSACLIQ 448

  Fly   200 -----DDTHTHIH-----FPDSNRS-------NPTEKSNQV-SLC--------GSL--EGVERAR 236
                 :|.:.:::     |||...|       .|.|:|..: .:|        |||  ..:.:..
Yeast   449 LEMEEEDDNLYLNLVSDSFPDFKESFKNVINEFPAEESFFIPEVCHRPIIGTGGSLIQATMRKHN 513

  Fly   237 ALVRLSTPLLISFEMPVMGPNKPQPDHETPYIKMIETKFNVQVIFSTRPKLHTSLVLVKGSEKES 301
            ..::.|.    ||.:|   .||         |.||...   .||.....|...::.|.|...|:.
Yeast   514 VFIQFSN----SFNLP---QNK---------ISMIRYD---NVIIRCPRKNKANICLAKNDLKQI 559

  Fly   302 AQVRDATQ--LLINFACESIASQILVNVQMEISPQHHEIVKGKNNVNLLSIMERTQTKIIFPDLS 364
            .|..|:.|  .||.|:                |.|:..|:......|::..:|:.:...|...|.
Yeast   560 VQEYDSLQSKTLIRFS----------------SGQYRHILHVNGQKNIIGQIEKNENVYIMIPLK 608

  Fly   365 DMNVKPLK-KSQVTISGRIDDVYLARQQLLGNLPVALIFDFP-DNHNDASEIMSLNTKYGVYITL 427
            :    ||. .||::|.|..::...|..:|: |......::|. |...|.      |.:|..|
Yeast   609 E----PLDGTSQLSIQGNDENASRAANELV-NSAFGYEYEFKIDQEIDP------NKEYEFY--- 659

  Fly   428 RQKQRQSTLAIVVKGVEKFIDKIYEARQEILRLATPFVKPEIPDYYFMPKDKDLNLAYRTQLTAL 492
                   .|.:|     .|:        :|:.:...|.|    |......:||.|....|:...|
Yeast   660 -------NLIVV-----PFL--------QIMNIIVTFEK----DLITFTFEKDTNENTLTKAIEL 700

  Fly   493 LAGYVDSPKT----PSLLPPSLAGQLTPYANNNHLLLNANGLATPTGVCAPTQKYMQLHNSFQQA 553
            |:.|:::.||    ..::...:.|..:..:|.:    |:|
Yeast   701 LSNYLETQKTKIIFKKIIKKFVLGSASSKSNTS----NSN------------------------- 736

  Fly   554 QNRSMVAGGQSNNGNYLQVPGAVAPPLKPPTVSPRNSCSQNTSGYQSFSSSTTSLEQSYPPYAQL 618
                       .|||:.               |..|:.|:.|       ...||...:.|...::
Yeast   737 -----------TNGNFR---------------SMNNAKSRTT-------IDNTSQSGASPQRHKM 768

  Fly   619 PGTVSSTSSSTAGSQNRAHYSPDSTYGSEGGGVG 652
            |     ..::..|:|....|.|::.|...|.|.|
Yeast   769 P-----VITTVGGAQAIKGYIPNTYYNGYGYGYG 797

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
BicC	NP_476865.1	KH-I_BICC1_rpt1	85..166	CDD:411848	24/120 (20%)
		KH-I_BICC1_rpt2	171..240	CDD:411849	19/104 (18%)
		KH-I_BICC1_rpt3	325..393	CDD:411850	14/68 (21%)
		SAM_BICC1	805..868	CDD:188919
YLL032C	NP_013068.1	COG5166	2..704	CDD:227495	115/587 (20%)