DRSC/TRiP Functional Genomics Resources

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Protein Alignment BicC and Hdlbpl2

DIOPT Version :10

Sequence 1:NP_476865.1 Gene:BicC / 34946 FlyBaseID:FBgn0000182 Length:905 Species:Drosophila melanogaster
Sequence 2:NP_001406472.1 Gene:Hdlbpl2 / 302773 RGDID:1563104 Length:1250 Species:Rattus norvegicus


Alignment Length:466 Identity:98/466 - (21%)
Similarity:191/466 - (40%) Gaps:97/466 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly    72 AIAMKLGVQNPDDLHTERFKVDRQKLEQLIKAESSIEGMNGAEYFFHDIMNTTDTYVSWPCRLK- 135
            ||..|:..:|...:    ..|...:|...|:.|....|:..|:....|:.|..:...|....:| 
  Rat   443 AILNKIAERNQVSI----TMVPENELNHTIRIEGESLGVQQAKKELLDLANNLEEEYSQDIIIKH 503

  Fly   136 ------IGAKSKK--------------DPH-------VRIVGKVDQVQRAKERILSSL-DSRGTR 172
                  ||.|.::              .||       |:::|...:.::..:.:.:.| |.:...
  Rat   504 QFHHILIGQKGERVREICKKFPDVILNFPHPAEKSDIVQLIGPRYESEKCAQYLENMLTDIKENN 568

  Fly   173 VIMKMDVSYTDHSYIIGRGGNNIKRIMDDTHTHIHFPDSNRSNPTEKSNQVSLCGSLEGVERARA 237
            ..:.:.:....|..:||:|.:|||:|.:.|:|.|.||..|.:     |.:..:.|..|..|.||.
  Rat   569 YSISISIIKKLHKRLIGKGASNIKKISETTNTKISFPPENCN-----SEEFIITGYPENCEIARN 628

  Fly   238 -LVRLSTPLLISFEMPVMGP-------NKPQPDHETPYIKMIETKFNVQVIFSTRPKLHTSL--V 292
             ::.:...:..:.|..:..|       |.|:   |.....:||....:.:.|   ||..:||  |
  Rat   629 WILSIQQEIADTAEEEITIPTNLYKYLNNPK---ECLLNSIIEECGKIHLHF---PKNKSSLNKV 687

  Fly   293 LVKGSEKESAQVRDATQLLINFACESIASQILVNVQMEISPQHHEIVKGKNNVNLLSIMERTQTK 357
            ::.||.:   .|..|...|:..|.|..|..  .:.::.:..|:|:.:..||..|:..|.:.|.|.
  Rat   688 IIMGSVE---SVEKAKAKLLKLAEEEQAKN--YSEKIRVKSQYHQFLVNKNGGNISQICDETGTC 747

  Fly   358 IIFPDLSDMNVKPLKKSQVTISGRIDDVYLARQQLLGNLPVALIFDFPDNHNDASEIMSLNTKY- 421
            ::||:.::.:     :..:||:|..:.|...:::|     ..|:.||   .|:..:.:.:|.:: 
  Rat   748 VLFPNHTNKD-----QESLTITGSEESVKEVQKRL-----EDLVKDF---ENEVDDSILINRRFH 799

  Fly   422 -------------------GVYITLRQKQRQSTLAIVVKGVEKFIDKIYEARQEILRLATPFVKP 467
                               ||.||.....||:| .:.:||.:..::   .|::.|..:..| :..
  Rat   800 HYFVMRRGQLLKEMTEEYGGVVITFSYAGRQNT-KVTIKGAKPCVE---AAKKHIKAIFEP-LGS 859

  Fly   468 EIPDYYFMPKD 478
            ::...|.:|::
  Rat   860 QVTTRYVIPQN 870

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
BicCNP_476865.1 KH-I_BICC1_rpt1 85..166 CDD:411848 17/108 (16%)
KH-I_BICC1_rpt2 171..240 CDD:411849 20/69 (29%)
KH-I_BICC1_rpt3 325..393 CDD:411850 14/67 (21%)
SAM_BICC1 805..868 CDD:188919
Hdlbpl2NP_001406472.1 KH-I 71..136 CDD:469614
KH-I_Vigilin_rpt5 352..420 CDD:411837
KH-I_Vigilin_rpt6 422..489 CDD:411804 11/49 (22%)
KH-I 494..560 CDD:469614 9/65 (14%)
KH-I_Vigilin_rpt8 570..631 CDD:411839 20/65 (31%)
KH-I 641..696 CDD:469614 15/63 (24%)
KH-I 713..778 CDD:469614 15/76 (20%)
KH-I 789..853 CDD:469614 12/67 (18%)
KH-I 866..952 CDD:469614 1/5 (20%)
KH-I 957..1033 CDD:469614
KH-I 1038..1110 CDD:469614
KH-I 1112..1177 CDD:469614
Blue background indicates that the domain is not in the aligned region.

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