DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3793 and LCMT1

DIOPT Version :9

Sequence 1:	NP_001246038.1	Gene:	CG3793 / 34928	FlyBaseID:	FBgn0028507	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	XP_011544166.1	Gene:	LCMT1 / 51451	HGNCID:	17557	Length:	357	Species:	Homo sapiens

Alignment Length:	288	Identity:	141/288 - (48%)
Similarity:	192/288 - (66%)	Gaps:	5/288 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 KRCAVRLGYWKDDYIGYFVR-NQERKAPEINRGYFARVKGVEMCVEKFLKKTSGNCQIINLGCGF 97
            :|.||.:|||.|.||.:||| ::|||||||||||||||.||...::.||:||..:|||:|||.|.
Human    60 RRFAVSIGYWHDPYIQHFVRLSKERKAPEINRGYFARVHGVSQLIKAFLRKTECHCQIVNLGAGM 124

  Fly    98 DTLYFRLRDTAHQVKNFIELDFPTVTARKCYTIKRNKAL---LARIHDEDGEVRLSPTDLHGPSY 159
            ||.::||:|.......:.|:|||.:..||.::||....|   :..:|.|| .:::....|....|
Human   125 DTTFWRLKDEDLLPSKYFEVDFPMIVTRKLHSIKCKPPLSSPILELHSED-TLQMDGHILDSKRY 188

  Fly   160 HLMGVDLRNLDEVDSKLQQAEVDYSLPTIFLAECVLVYIEAQNCRNLLKWIAQKFQAAVFVNYEQ 224
            .::|.|||:|.|::.||::..::..|||:.:|||||||:..:...|||||.|..|:.|:|:||||
Human   189 AVIGADLRDLSELEEKLKKCNMNTQLPTLLIAECVLVYMTPEQSANLLKWAANSFERAMFINYEQ 253

  Fly   225 VNMNDRFGDVMLNNLRGRGCSLAGVESCLSLDTQRNRFKDSGWTGARAWDMVQVYESISAAERQR 289
            |||.||||.:|:.|||.|.|.|||||:|.||::|:.|...:||..|.|.||:::|..:..||..|
Human   254 VNMGDRFGQIMIENLRRRQCDLAGVETCKSLESQKERLLSNGWETASAVDMMELYNRLPRAEVSR 318

  Fly   290 IERLEMLDEGELLLQLFQHYCLVVAWLG 317
            ||.||.|||.|||.||.:||||..|..|
Human   319 IESLEFLDEMELLEQLMRHYCLCWATKG 346

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3793	NP_001246038.1	LCM	22..211	CDD:397957	82/180 (46%)
LCMT1	XP_011544166.1	LCM	67..240	CDD:309269	79/173 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150783
Domainoid	1	1.000	173	1.000	Domainoid score	I3715
eggNOG	1	0.900	-	-		E1_KOG2918
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H41123
Inparanoid	1	1.050	295	1.000	Inparanoid score	I2761
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53717
OrthoDB	1	1.010	-	-		D1094856at2759
OrthoFinder	1	1.000	-	-		FOG0001575
OrthoInspector	1	1.000	-	-		oto88330
orthoMCL	1	0.900	-	-		OOG6_100931
Panther	1	1.100	-	-	LDO	PTHR13600
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2177
SonicParanoid	1	1.000	-	-		X3234
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.800