DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3793 and Lcmt1

DIOPT Version :9

Sequence 1:	NP_001246038.1	Gene:	CG3793 / 34928	FlyBaseID:	FBgn0028507	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_079580.2	Gene:	Lcmt1 / 30949	MGIID:	1353593	Length:	332	Species:	Mus musculus

Alignment Length:	323	Identity:	154/323 - (47%)
Similarity:	209/323 - (64%)	Gaps:	16/323 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 IAGSTHK--FHPC-------DEAVIATNDDASDCKRCAVRLGYWKDDYIGYFVR-NQERKAPEIN 63
            :|.|:.:  |..|       ||.|..|.:|||.|||.||.:|||.|.||.:.|| ::||||||||
Mouse     1 MASSSRESSFSSCSSSCDLDDEGVRGTCEDASLCKRFAVSIGYWHDPYIEHLVRQSKERKAPEIN 65

  Fly    64 RGYFARVKGVEMCVEKFLKKTSGNCQIINLGCGFDTLYFRLRDTAHQVKNFIELDFPTVTARKCY 128
            |||||||.||...::.||:||..:|||:|||.|.||.:::|:|.......:.|:|||.:..||..
Mouse    66 RGYFARVHGVSQLIKAFLRKTECHCQILNLGAGMDTTFWKLKDEGLLPNKYFEVDFPMIVTRKLL 130

  Fly   129 TIKRNKALLAR----IHDEDGEVRLSPTDLHGPSYHLMGVDLRNLDEVDSKLQQAEVDYSLPTIF 189
            ||| :|.||.|    :|.|| .:::....|....|.::|.|||:|.|::.||::..::..|||:.
Mouse   131 TIK-SKPLLFRPIMELHPED-TLQMDSHMLDSKRYAIIGADLRDLSELEEKLKKCNMNTQLPTLL 193

  Fly   190 LAECVLVYIEAQNCRNLLKWIAQKFQAAVFVNYEQVNMNDRFGDVMLNNLRGRGCSLAGVESCLS 254
            :.||||||:..:...|||||.|..|:.|:|:|||||||:||||.:|:.|||.|.|.|||||:|.|
Mouse   194 ITECVLVYMTPEQSANLLKWAASSFETAMFINYEQVNMDDRFGQIMIENLRRRSCDLAGVETCKS 258

  Fly   255 LDTQRNRFKDSGWTGARAWDMVQVYESISAAERQRIERLEMLDEGELLLQLFQHYCLVVAWLG 317
            |::|:.|...:||..|.|.:|:::|..:..||..|||.||.|||.|||.||.:||||..|..|
Mouse   259 LESQKERLLLNGWETASAVNMMELYSGLPRAEVNRIESLEFLDEMELLEQLMRHYCLCWATRG 321

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3793	NP_001246038.1	LCM	22..211	CDD:397957	90/193 (47%)
Lcmt1	NP_079580.2	LCM	24..215	CDD:281992	90/192 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167840845
Domainoid	1	1.000	170	1.000	Domainoid score	I3773
eggNOG	1	0.900	-	-		E1_KOG2918
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H41123
Inparanoid	1	1.050	290	1.000	Inparanoid score	I2785
Isobase	1	0.950	-	0.815465	Normalized mean entropy	S2071
OMA	1	1.010	-	-		QHG53717
OrthoDB	1	1.010	-	-		D1094856at2759
OrthoFinder	1	1.000	-	-		FOG0001575
OrthoInspector	1	1.000	-	-		oto91903
orthoMCL	1	0.900	-	-		OOG6_100931
Panther	1	1.100	-	-	LDO	PTHR13600
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2177
SonicParanoid	1	1.000	-	-		X3234
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	17	16.750