DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3793 and lcmt2

DIOPT Version :9

Sequence 1:	NP_001246038.1	Gene:	CG3793 / 34928	FlyBaseID:	FBgn0028507	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	XP_031753467.1	Gene:	lcmt2 / 100144923	XenbaseID:	XB-GENE-5944136	Length:	895	Species:	Xenopus tropicalis

Alignment Length:	302	Identity:	107/302 - (35%)
Similarity:	157/302 - (51%)	Gaps:	11/302 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 VIATNDDASDCKRCAVRLGYWKDDYIGYFVRNQERKAPEINRGYFARVKGVEMCVEKFLKKTSGN 87
            |.:|||.::..|..|..|||::|:|...||....|::|.|:|||..|.:.|..|:.:|::.|. :
Frog   235 VQSTNDCSTLSKVSAASLGYFEDEYQKNFVNRNCRRSPLIHRGYCVRSQAVTHCINEFIRDTQ-S 298

  Fly    88 C---QIINLGCGFDTLYFRLRDTAHQVKNFIELDFPTVTARKCYTIKRN---KALLARIHDEDGE 146
            |   |:::||||||:|:||||..:.......|:|||:|..|||..|:::   :.||......||.
Frog   299 CDHRQVVSLGCGFDSLFFRLRMQSESPLCVWEVDFPSVVKRKCLLIEQSGDLRDLLGSYVTPDGN 363

  Fly   147 VRLSPTDLHGPSYHLMGVDLRNLDEVDSKLQQAEVDYSLPTIFLAECVLVYIEAQNCRNLLKWIA 211
               .|..|....|.|:||||..:..:|:.|..|.:.:..||:.|.|..|.|::......|:.|.|
Frog   364 ---GPLVLLSQGYKLLGVDLTEVSSLDAALNLAGLSWDCPTLVLGEVALCYMDPARSTALIGWAA 425

  Fly   212 QKFQAAVFVNYEQVNMNDRFGDVMLNNLRGRGCSLAGVESCLSLDTQRNRFKDSGWTGARAWDMV 276
            ::|:.:.||.|||...:|.||.||.::.......|..:.....:..|..||...||...||.||.
Frog   426 ERFRDSRFVLYEQSCPSDPFGRVMTSHFASLNSPLLSLSEFPHIQDQEQRFLHKGWKTCRALDMN 490

  Fly   277 QVYES-ISAAERQRIERLEMLDEGELLLQLFQHYCLVVAWLG 317
            :...| :...|.|||..||..||.|.|.....||.::||..|
Frog   491 EFCASCVPLPEVQRIHNLEPFDEFEELHLKCSHYFILVASQG 532

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3793	NP_001246038.1	LCM	22..211	CDD:397957	69/193 (36%)
lcmt2	XP_031753467.1	AdoMet_MTases	247..425	CDD:418430	64/181 (35%)
		KELCH repeat	685..736	CDD:276965
		KELCH repeat	740..787	CDD:276965
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1094856at2759
OrthoFinder	1	1.000	-	-		FOG0001575
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010