Protein Alignment: Gli and Ces2a

• Sequence 1: NP_476602.1
• Gene: Gli
• FlyBaseID: FBgn0001987
• Length: 956
• Species: Drosophila melanogaster
• Sequence 2: NP_653344.1
• Gene: Ces2a
• RGDID: 708353
• Length: 558
• Species: Rattus norvegicus
• Alignment Length: 644
• Identity: 190/645 (29%)
• Similarity: 278/645 (43%)
• Gaps: 143/645 (22%)

  Fly   103 PNARTQFPG----VLAGWREDLQGKQRRDSLTLERDVFVTTNYGQVQGFKVYMYDNPDPKSFYRP 163
            |.||  .||    |..|....||....:||.:..|:    |:.|||:|..|::   .|.||   .
  Rat     2 PLAR--LPGWLYVVACGLLLLLQHVHGQDSASPIRN----THTGQVRGSFVHV---KDTKS---G 54

  Fly   164 YHSTVDRVMGECSVFLGIPYALPPTFEGRFKPPRVHRGWQLLQAVDFGPA-CPQP-------VRY 220
            .|:           |||||:|.||....||.||.....|..::.....|| |.|.       ::.
  Rat    55 IHT-----------FLGIPFAKPPVGPLRFAPPEDPEPWSGVRDATSQPAMCLQTDIMNLDGIKE 108

  Fly   221 TGATKGIMDMDEDCLYLNVYSPKTGAGVAQKYPVMVYIHGGEFIRGASNLFQGHILASFYDVVVV 285
            ...|.....|.|||||||:|:| ..|......||||:||||..:.|::::.....||:..::|:|
  Rat   109 MKLTVHPTPMSEDCLYLNIYTP-AHAREGSNLPVMVWIHGGGLVLGSASMNDASTLAATEEIVIV 172

  Fly   286 TLNYRLGALGFLSTGDENSPGNYGILDQAMALRWVYDNIEFFNGDRNSITLFGPGAGGASAGLLM 350
            ::.||||.|||.||||:|:.||:|.|||..|||||..||.:|.|:...:|:||..|||.|....:
  Rat   173 SIQYRLGVLGFFSTGDQNARGNWGYLDQVAALRWVQQNIAYFGGNHGKVTIFGGSAGGTSVSSHV 237

  Fly   351 VAPQTRNIVRRVIAQSGSALADWALIQDKYRAQNTSRVLGQLLGCSIESSWKLVNCLRTGRSFYE 415
            |:|.::.:....|.|||.||.. .||.||  ::...:.:..|.||....|..|:.||| .:|..|
  Rat   238 VSPMSKGLFHGAIMQSGVALLP-DLISDK--SEVVYKTVANLSGCEAPDSEALIRCLR-AKSKQE 298

  Fly   416 L--GNAEFSPQVGSFPWGPVLDHNFTLPGDDWYEGWREKDWRFLTQTPETLIRAGKFNRNIQYMT 478
            :  .|..|.                .:||        ..|.:||.:.|:.|:.:|.|: .:..:.
  Rat   299 ILAINQVFK----------------MIPG--------VVDGKFLPKHPQELLASGDFH-PVPSII 338

  Fly   479 GVTTQEAAFFVAQNESLSPYYELDGRFFDQKIREHVFR---------------YNYTLNPNGVYE 528
            |:.|.|..:      .:..:..||          |:.:               ....|.|    |
  Rat   339 GINTDECGW------GIPVFLGLD----------HIIKKITRETLPTVLKSTAAQMMLPP----E 383

  Fly   529 AIKYIY-TFWPDPNNNTIIRDQYINMLSDLYYRAPVDQMVKLMLEQKVPVYMYVLNTTVEALNLP 592
            .|..|. .:..|..|...:::|:.:||.|..:..|..|:......| .|||.|      |..:||
  Rat   384 CIDLIMEEYMGDTENPETLQEQFRHMLGDFMFVIPALQVAHFQRSQ-APVYFY------EFQHLP 441

  Fly   593 QWRKY--PHDIER-----------YFLTGAPFMDTEFFPKKEHLQRNMWTDNDRNMSHFFMQTYT 644
            .:.|.  |..::.           .:|.|..|..||   ::|.|:|.:            |:.:.
  Rat   442 SFIKQVRPSHVKADHGDDILFVFGSYLWGMTFDLTE---EEELLKRRV------------MKYWA 491

  Fly   645 NFARYGNPTPQQVLGMHFQRAYQGEIRYLNINTTYNSSILLNYRQTECAFWTQYLPTVI 703
            ||||.|||..:.:  .|:......| :||.:||.......|..|:.:  |||:.||..|
  Rat   492 NFARTGNPNGEDL--PHWPVLDHDE-QYLQLNTQPAVGRALKARRLQ--FWTKTLPQKI 545

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gli	NP_476602.1	COesterase	134..695	CDD:278561	173/600 (29%)
Ces2a	NP_653344.1	COesterase	30..537	CDD:278561	174/605 (29%)
		Aes	70..>230	CDD:223730	66/161 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C90132087
eggNOG	1	0.900				E1_COG2272
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010				D754103at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.840