Protein Alignment Gli and cest-26

DIOPT Version :9

• Sequence 1: NP_476602.1
• Gene: Gli / 34927
• FlyBaseID: FBgn0001987
• Length: 956
• Species: Drosophila melanogaster
• Sequence 2: NP_001368609.1
• Gene: cest-26 / 180715
• WormBaseID: WBGene00017478
• Length: 585
• Species: Caenorhabditis elegans
• Alignment Length: 606
• Identity: 169/606 - (27%)
• Similarity: 259/606 - (42%)
• Gaps: 121/606 - (19%)

  Fly   137 VTTNYGQVQGFKVYMYDNPDPKSFYRPYHSTVDRVMGECSVFLGIPYALPPTFEGRFKPPRVHRG 201
            |.|..|.|:||::.:.|               ||   |..:|||||:|..|..:.|||.|.....
 Worm    44 VRTRNGLVEGFRIKIDD---------------DR---EVDMFLGIPFAKAPVGDLRFKNPEHTED 90

  Fly   202 WQ-LLQAVDFGPACPQP----VRYT-GATKGIMDMDEDCLYLNVYSPKTGAGVAQK--YPVMVYI 258
            |. :.:.|.|||..||.    .|:| |..|     .||||||||:||...|.....  :|||||:
 Worm    91 WDGVKKCVRFGPRAPQADFFWERFTLGVGK-----SEDCLYLNVFSPTWKAEEVSNGLHPVMVYV 150

  Fly   259 HGGEFIRGASNLFQGHILASF---YDVVVVTLNYRLGALGFLSTGDENSPGNYGILDQAMALRWV 320
            |||.|:..::..:....:|.:   :.|||||:.||||.|||.||||:..|||.|:.|..|||:||
 Worm   151 HGGGFLIDSAVKYGDEGIAKYLCRHGVVVVTIQYRLGLLGFFSTGDQVCPGNLGLWDMTMALQWV 215

  Fly   321 YDNIEFFNGDRNSITLFGPGAGGASAGLLMVAPQTRNIVRRVIAQSGSALADWALI--------- 376
            .||:..|.||...:|:||..|||.|..||.::|.:|::..:|:..:|:...:|:.:
 Worm   216 RDNVHAFGGDPRKVTVFGQSAGGVSVDLLSLSPHSRDLFHQVVPMAGNGECEWSTVGKNRLVNAC 280

  Fly   377 ----------QDKYRAQNTSRVLGQLLGCSIESSWKLVNCLRTGRSFYELGNAEFSPQVGSFPWG 431
                      :.:.|.:|.|..:.:.|....|..::.....|.|....::| .:.:|.:||
 Worm   281 REFAYRKCWDEKQARDENASESMLEFLRTRKEREFEKRLLTRKGVDVSKIG-LDLAPVIGS---- 340

  Fly   432 PVLDHNFTLPGDDWYEGWREKDWRFLTQTPETLIRAGKFNRNIQYMTGVTTQEAAFFVAQNESLS 496
                    .|.|            ||.::.|.| |.....:||  |.|....|...|.    ||.
 Worm   341 --------KPSD------------FLPKSIEEL-RKEAPKKNI--MVGTCEHEGLLFA----SLG 378

  Fly   497 PYYELDGRFFDQKIREHVFRYNYTLNPNGVYEAIK------YIYTFWPDPNNNTIIRDQYINMLS 555
            |      ..||:|..:.:.....|...:..:||::      |:.....|.::..:....||.:.|
 Worm   379 P------SNFDEKGIDKLLALLITEENHEDFEALREEAKKMYLKKLSDDEDDKEVAARGYIQLYS 437

  Fly   556 DLYYRAPVDQMVKLMLEQKVPVYMYVLNTT------VEALNLPQWRKYPHDIERYFLTGAPFMDT 614
            ||:.........:.|.:....|:||..:..      :.:|..| :|...|..|..::.|...:
 Worm   438 DLFVNNGTYNYAEKMTKLGNKVFMYSFDYCNPRSFGILSLRAP-FRAATHCTELAYIFGVSIV-- 499

  Fly   615 EFFPKKEHLQRNMWTDNDRNMSHFFMQTYTNFARYGNPTPQ----QVLGMHFQRAYQGE-IRYLN 674
              |..:       :.::||.|.....:.:||||:||||..|    .|....::...:.| ..:|.
 Worm   500 --FNYR-------YNESDRAMLDLMTKMWTNFAKYGNPNGQYEDSTVFDFKWEPTSKEEPTNFLA 555

  Fly   675 INTTYNSSILLNYRQTECAFW 695
            ||.. ...:...|:.....||
 Worm   556 INEK-KCEMQTVYQDNRAEFW 575

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gli	NP_476602.1	COesterase	134..695	CDD:278561	167/604 (28%)
cest-26	NP_001368609.1	COesterase	40..575	CDD:395084	167/604 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810