Protein Alignment CycE and CycA

DIOPT Version :10

• Sequence 1: NP_001246037.1
• Gene: CycE / 34924
• FlyBaseID: FBgn0010382
• Length: 712
• Species: Drosophila melanogaster
• Sequence 2: NP_524030.2
• Gene: CycA / 39340
• FlyBaseID: FBgn0000404
• Length: 491
• Species: Drosophila melanogaster
• Alignment Length: 352
• Identity: 93/352 - (26%)
• Similarity: 159/352 - (45%)
• Gaps: 73/352 - (20%)

  Fly   168 QSTQELLSIRSSPAEDLSEAPHS--PLPDSPDSPPSP--------DRGSKQTPVVVRYAAEQVVT 222
            ::|::.|::....||..:.||.:  .:.:..::.|.|        |..:......|.|.|::...
  Fly    25 KNTKQPLAVIGGKAEKNALAPRANFAVLNGNNNVPRPAGKVQVFRDVRNLNVDENVEYGAKKSNV 89

  Fly   223 STVVTQ-KTEDDDLLDDSCEDYSYDEDDEDD------------VEEEDDDVEIYSSTISPASSGC 274
            ..||.| ||            :|..||:.|.            |::|:.||:.          |.
  Fly    90 VPVVEQFKT------------FSVYEDNNDTQVAPSGKSLASLVDKENHDVKF----------GA 132

  Fly   275 SQQQAVNGERTPGLPKHQEQIHHPV------------SDLMINMRTPMSPAVENGLRQCP----- 322
            .|::.|:.: ....|.....:..|:            ||:.:...|.:||.  ..:::.|
  Fly   133 GQKELVDYD-LDSTPMSVTDVQSPMSVDRSILGVIQSSDISVGTETGVSPT--GRVKELPPRNDR 194

  Fly   323 ---LPALAWANAADVWRLMCHRDEQDSRLRSISMLEQHPGLQPRMRAILLDWLIEVCEVYKLHRE 384
               |..:.:  ..|:.... ...|:..|.:.:.|..| ..:...||:||:|||:||.|.|||..|
  Fly   195 QRFLEVVQY--QMDILEYF-RESEKKHRPKPLYMRRQ-KDISHNMRSILIDWLVEVSEEYKLDTE 255

  Fly   385 TFYLAVDYLDRYLHVAHKVQKTHLQLIGITCLFVAAKVEEIYPPKIGEFAYVTDGACTERDILNH 449
            |.||:|.||||:|. ...|.::.|||:|...:::|||.||||||::|||.::||.:.|:..:|..
  Fly   256 TLYLSVFYLDRFLS-QMAVVRSKLQLVGTAAMYIAAKYEEIYPPEVGEFVFLTDDSYTKAQVLRM 319

  Fly   450 EKILLQALDWDISPITITGWLGVYMQL 476
            |:::|:.|.:|:...|...::..|..|
  Fly   320 EQVILKILSFDLCTPTAYVFINTYAVL 346

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CycE	NP_001246037.1	CYCLIN_CCNE_rpt1	327..459	CDD:410223	52/131 (40%)
		CYCLIN_CCNE_rpt2	463..576	CDD:410224	3/14 (21%)
CycA	NP_524030.2	CYCLIN_CCNA_rpt1	202..329	CDD:410208	52/131 (40%)
		Cyclin_C	334..450	CDD:397230	3/13 (23%)