DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG15253 and Semp1

DIOPT Version :9

Sequence 1:	NP_609758.1	Gene:	CG15253 / 34916	FlyBaseID:	FBgn0028948	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	NP_609756.1	Gene:	Semp1 / 34914	FlyBaseID:	FBgn0028944	Length:	251	Species:	Drosophila melanogaster

Alignment Length:	228	Identity:	104/228 - (45%)
Similarity:	141/228 - (61%)	Gaps:	8/228 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 DPELTAGYIEGDMVPSG-SSRNIWRNETYRWPNRIIYYHI--NSYIDEEHRNHIVSAIQKIESIS 89
            ||||.||:.:||:.... .:||...|:.|.||||.:.|.|  :::.|..:| .|:.||..||..|
  Fly    23 DPELLAGFYQGDIKAHPIRTRNGIVNQIYHWPNRTVPYMIEDDAFADSHYR-EILRAISIIEENS 86

  Fly    90 CLTFKEAT-TDQKYYVNVTSEEGGCFS-YIGYLNRVQQLNLQNNEIGVGCFRLYTIVHEFLHALG 152
            |:.||.|| .|....:.:||:..||.: ::||.|:.|.:||:...:|.||||:.:|:||.||.||
  Fly    87 CVIFKPATEMDFPMALVITSKGLGCNTVHLGYRNKTQVVNLEIYPLGEGCFRIGSIIHELLHVLG 151

  Fly   153 FFHQQSAADRDDYVQIVEENITEGMEFNFDKYTEETV-NDFGEKYDYGSVMHYGPYAFSKNGERT 216
            |.||..:.:||.||.|..:||......||......|. :||.|.|||.|||||.|.|||:||:.|
  Fly   152 FEHQHVSQNRDQYVSIQWKNINPQYNINFVNNDNSTAWHDFDEGYDYESVMHYVPRAFSRNGQPT 216

  Fly   217 ILALEEGKEDVIGQRLELSETDIRKLNAIYKCP 249
            |:.|.||.|: :|||..:||.||||||.:|:||
  Fly   217 IVPLREGAEN-MGQRFYMSEKDIRKLNKMYRCP 248

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15253	NP_609758.1	Astacin	55..250	CDD:279708	93/200 (47%)
CG15253	NP_609758.1	ZnMc_astacin_like	59..246	CDD:239807	87/191 (46%)
Semp1	NP_609756.1	Astacin	53..249	CDD:279708	92/198 (46%)
Semp1	NP_609756.1	ZnMc_astacin_like	55..245	CDD:239807	87/191 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45444828
Domainoid	1	1.000	145	1.000	Domainoid score	I4540
eggNOG	1	0.900	-	-		E1_KOG3714
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG49330
OrthoDB	1	1.010	-	-		D109979at50557
OrthoFinder	1	1.000	-	-		FOG0000240
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	8	7.860