DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15253 and astl2d.2

DIOPT Version :9

Sequence 1:	NP_609758.1	Gene:	CG15253 / 34916	FlyBaseID:	FBgn0028948	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	XP_031756346.1	Gene:	astl2d.2 / 105947175	XenbaseID:	XB-GENE-22069740	Length:	517	Species:	Xenopus tropicalis

Alignment Length:	218	Identity:	73/218 - (33%)
Similarity:	118/218 - (54%)	Gaps:	16/218 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 IEGDMVPSGSSRNIWRNETYRW--PNRIIY--YHINSYIDEEHRNHIVSAIQKIESISCLTFKEA 96
            ::||:....|...|...:.: |  .|.|:|  |.::.....:..|.|.||::...:::|:.| ..
Frog    79 VQGDIAVRVSRSTIVCTDCF-WQKSNGIVYVPYTLDKQYSSDQINTITSAMEVYSTLTCVQF-VP 141

  Fly    97 TTDQKYYVNVTSEEGGCFSYIGYLNRVQQLNLQNNEIGVGCFRLYTIVHEFLHALGFFHQQSAAD 161
            .||::.|:.:||.: ||:||:|.....|.::::...    |....|.:||..|||||.|:||.:|
Frog   142 YTDEEDYIAITSGD-GCWSYMGRQGGAQVVSVEKGY----CTSEGTTMHELNHALGFVHEQSRSD 201

  Fly   162 RDDYVQIVEENITEGMEFNFDKYTEETVNDFGEKYDYGSVMHYGPYAFSK-NGERTILALEEGKE 225
            ||:||.|:.:.|:.|...||.|.  || |:....|||.|:|||..:|||. .|:.||:| :....
Frog   202 RDNYVDIMYQYISPGDIVNFKKM--ET-NNLNTTYDYHSIMHYPAWAFSNTTGQNTIVA-KLNPN 262

  Fly   226 DVIGQRLELSETDIRKLNAIYKC 248
            ..:|....::..||.|:|.:|:|
Frog   263 TPLGPGSTMTNLDITKINRLYQC 285

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15253	NP_609758.1	Astacin	55..250	CDD:279708	69/199 (35%)
CG15253	NP_609758.1	ZnMc_astacin_like	59..246	CDD:239807	66/189 (35%)
astl2d.2	XP_031756346.1	ZnMc	103..285	CDD:412141	67/191 (35%)
		CUB	288..399	CDD:238001
		CUB	402..513	CDD:238001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D681837at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010