DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15253 and astl2d.4

DIOPT Version :9

Sequence 1:	NP_609758.1	Gene:	CG15253 / 34916	FlyBaseID:	FBgn0028948	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	XP_004913426.2	Gene:	astl2d.4 / 101734297	XenbaseID:	XB-GENE-22069748	Length:	537	Species:	Xenopus tropicalis

Alignment Length:	220	Identity:	73/220 - (33%)
Similarity:	117/220 - (53%)	Gaps:	20/220 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 IEGDMVPSGSSRNIWRNETYRWP--NRIIYYHINSYIDEEHRNH----IVSAIQKIESISCLTFK 94
            ::|| :..|.||:........||  |..:|  :...:|:|:.|:    |.:|:|...:::|:.|
Frog    99 VQGD-IAIGVSRSALNCTNCLWPKTNGTVY--VPYTLDDEYSNNEVNTITAAMQVYATLTCVQF- 159

  Fly    95 EATTDQKYYVNVTSEEGGCFSYIGYLNRVQQLNLQNNEIGVGCFRLYTIVHEFLHALGFFHQQSA 159
            ...||:..||.:.| ..||:||:|.....|.::::...    |....|.:||..|||||.|:||.
Frog   160 VPYTDEDDYVAIKS-ANGCWSYMGRQGGAQVVSVEKGY----CTSEGTTMHELNHALGFVHEQSR 219

  Fly   160 ADRDDYVQIVEENITEGMEFNFDKYTEETVNDFGEKYDYGSVMHYGPYAFSK-NGERTILALEEG 223
            :|||:||.|:.:.|:.|...||:......:|..   |||.|:|||..:|||. .|:.||:| :..
Frog   220 SDRDNYVNIMYQYISPGDIVNFEIMNTNNLNTI---YDYRSIMHYPAWAFSNTTGQNTIVA-KPN 280

  Fly   224 KEDVIGQRLELSETDIRKLNAIYKC 248
            ...:||....::..||.|:|.:|:|
Frog   281 PNIIIGAGSTMTSLDIIKINRLYEC 305

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15253	NP_609758.1	Astacin	55..250	CDD:279708	68/201 (34%)
CG15253	NP_609758.1	ZnMc_astacin_like	59..246	CDD:239807	64/191 (34%)
astl2d.4	XP_004913426.2	ZnMc_hatching_enzyme	123..305	CDD:239810	65/193 (34%)
		CUB	308..417	CDD:395345
		CUB	422..533	CDD:238001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D681837at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010