DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment wor and CG4424

DIOPT Version :9

Sequence 1:	NP_476601.1	Gene:	wor / 34906	FlyBaseID:	FBgn0001983	Length:	548	Species:	Drosophila melanogaster
Sequence 2:	NP_650859.3	Gene:	CG4424 / 42390	FlyBaseID:	FBgn0038765	Length:	345	Species:	Drosophila melanogaster

Alignment Length:	284	Identity:	79/284 - (27%)
Similarity:	113/284 - (39%)	Gaps:	63/284 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   270 CQQCNKCYATYA-------GLVKH--QQ----------THAYESTEYKIIRSQPGGSGAIVDQTE 315
            ||:.|:....|.       |:||.  ||          |...|..|.:::..   |..:..|..|
  Fly    82 CQRSNEFLREYVIKDAVEQGVVKEVVQQTRPSTPPPIETEQLEPPEDEVLEE---GVWSTEDPIE 143

  Fly   316 FCTDQASALIQAANVASAQSMQKPVGVPRYHCQDCGKSYSTYSGLSKHQQFHCPSAEGNQVK-KV 379
            . |....|..:...|.:.:.:..|...|.          ||           .|.|....|| |:
  Fly   144 E-TPHGPAEKERPTVLTVEMLPAPYPPPA----------ST-----------PPPAPAGAVKGKL 186

  Fly   380 FSCKNCDKTYVSLGALKMHIRTHT--LPCKCPICGKAFSRPWLLQGHIRTHTGEKPFSCQHCNRA 442
            ..|..|...|.....|..|:|.|.  .|.:|.||.|:|...:.|:.|||.|||.||::||:|.|.
  Fly   187 HVCAICGNGYPRKSTLDTHMRRHNDERPYECEICHKSFHVNYQLKRHIRQHTGAKPYTCQYCQRN 251

  Fly   443 FADRSNLRAHMQTHSDVKKYSCPTCTKSFSRMSLLAKHLQSG-------CQTEQSGGPSGSGGGF 500
            ||||::|..|.:||.:.:.|:|.||.|.|:..|:|..|.::.       ||.        ....|
  Fly   252 FADRTSLVKHERTHRNERPYACKTCGKKFTYASVLKMHYKTHTGEKPHICQL--------CNKSF 308

  Fly   501 DQ-QQLQQHLQVYEEGHNPHQLYY 523
            .: ..|..|||..:..::|....|
  Fly   309 ARIHNLVAHLQTQQHINDPRLTAY 332

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wor	NP_476601.1	C2H2 Zn finger	270..290	CDD:275368	9/38 (24%)
		C2H2 Zn finger	317..334	CDD:275368	3/16 (19%)
		zf-C2H2	345..367	CDD:278523	2/21 (10%)
		C2H2 Zn finger	347..367	CDD:275368	2/19 (11%)
		PHA00732	379..>417	CDD:177300	13/39 (33%)
		C2H2 Zn finger	382..402	CDD:275368	6/19 (32%)
		zf-C2H2_8	405..482	CDD:292531	36/76 (47%)
		zf-C2H2	406..428	CDD:278523	9/21 (43%)
		C2H2 Zn finger	408..428	CDD:275368	9/19 (47%)
		zf-H2C2_2	421..444	CDD:290200	13/22 (59%)
		zf-C2H2	434..456	CDD:278523	10/21 (48%)
		C2H2 Zn finger	436..456	CDD:275368	10/19 (53%)
		zf-H2C2_2	448..473	CDD:290200	10/24 (42%)
		C2H2 Zn finger	464..481	CDD:275368	7/16 (44%)
CG4424	NP_650859.3	zf-AD	10..92	CDD:285071	3/9 (33%)
		C2H2 Zn finger	189..209	CDD:275368	6/19 (32%)
		DUF45	<204..281	CDD:302795	35/76 (46%)
		COG5048	210..>345	CDD:227381	45/131 (34%)
		C2H2 Zn finger	217..237	CDD:275368	9/19 (47%)
		C2H2 Zn finger	245..265	CDD:275368	10/19 (53%)
		zf-H2C2_2	257..282	CDD:290200	10/24 (42%)
		C2H2 Zn finger	273..293	CDD:275368	8/19 (42%)
		zf-H2C2_2	286..310	CDD:290200	5/31 (16%)
		C2H2 Zn finger	301..320	CDD:275368	6/26 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24409
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100