DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment nht and si:dkey-219c3.2

DIOPT Version :9

Sequence 1:	NP_523574.4	Gene:	nht / 34902	FlyBaseID:	FBgn0041103	Length:	245	Species:	Drosophila melanogaster
Sequence 2:	XP_005163125.1	Gene:	si:dkey-219c3.2 / 564106	ZFINID:	ZDB-GENE-090313-238	Length:	976	Species:	Danio rerio

Alignment Length:	292	Identity:	66/292 - (22%)
Similarity:	121/292 - (41%)	Gaps:	69/292 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 VPIQPYAGQLLIINDLILPDSGS-QD-------ASKAKVSI-KKNQR------------------ 45
            |.|...|.|...:||   |..|: :|       ||.|.|:: ::|.|
Zfish   697 VAIHASANQKQKLND---PGGGTFRDDDDINDVASMAGVNLNEENARILATGSELVGTQIRSCKD 758

  Fly    46 ASFFDRSSIYKKIMKHLSQGNQADDINISEQEWLLDSFLA-ALETYMKHVVKKTIELCEHRTSYH 109
            .:|...|.::|::::      .|....::|......:.:: |.::.::.:::|...:.:||.. .
Zfish   759 EAFLPASLLHKRLLE------TAKKFGVTEVSMETVTLISHATQSRLRSMLEKVSAVAQHRAD-S 816

  Fly   110 LHNDERCVMKNDMRVTMMFLNDLEIADYGSSDDETG--FYRKRRAENIDEERKVARLE------- 165
            ..:::.....:|:|..:.|...||..:....|||..  ..:..::.:..|:.:.|||:
Zfish   817 CKDEDLYEQTSDVRTQLKFFEQLEKIEKQRKDDEERELLMKAAKSRSRQEDPEQARLKQKAKEMQ 881

  Fly   166 ----------SVNDTALLAISGRKR-----PGEQLAPESAPSGSKVAKLTGAPIQ-----RACAP 210
                      ..|.|||.||..||:     ||.....| .|:||. ...||:...     |....
Zfish   882 QQELAQMRQRDANLTALAAIGPRKKRKLDSPGASAGAE-LPAGSS-GSATGSTSSSSSSVRQTRQ 944

  Fly   211 RFKHMNIRDVLQFMEEDRRYARSNMLFEAYLK 242
            |...:|:||::..:|::|..|||.:|::|.||
Zfish   945 RITRVNLRDLIFCLEQERTTARSTLLYKALLK 976

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nht	NP_523574.4	TAF4	10..238	CDD:173965	62/284 (22%)
si:dkey-219c3.2	XP_005163125.1	TAFH	531..616	CDD:284862
si:dkey-219c3.2	XP_005163125.1	TAF4	723..973	CDD:283017	54/258 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2341
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001841
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR15138
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	3.000