DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment nht and Taf4

DIOPT Version :9

Sequence 1:	NP_523574.4	Gene:	nht / 34902	FlyBaseID:	FBgn0041103	Length:	245	Species:	Drosophila melanogaster
Sequence 2:	NP_001074561.1	Gene:	Taf4 / 228980	MGIID:	2152346	Length:	1042	Species:	Mus musculus

Alignment Length:	324	Identity:	71/324 - (21%)
Similarity:	117/324 - (36%)	Gaps:	98/324 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 ISLEVPIQPYAGQLL---IINDLILPDS------GSQDASKAKVSIKKNQRASFFDRSSIYKKIM 59
            |.|..|.|....||.   ::...:||.:      .:|.|:..|..:|:....||.|...|
Mouse   732 IMLTTPQQIQLNQLQPVPVVKPTVLPGTKALSTVSAQAAAAQKNKLKEPGGGSFRDDDDI----- 791

  Fly    60 KHLSQGNQADDINISEQEWLL-----------------DSFL-------AALETYMKHVVKK--- 97
               :.......:|:||:...:                 |:||       ..||...||.:.:
Mouse   792 ---NDVASMAGVNLSEESARILATNSELVGTLTRSCKDDTFLLPAPLQRRILEIGKKHGITELHP 853

  Fly    98 -TIELCEHRTSYHLHN------------------DERCVMKNDMRVTMMFLNDLEIADYGSSDDE 143
             .:....|.|...|.|                  |:|....:|:|..:.|...|:..:....|::
Mouse   854 DVVSYVSHATQQRLQNLVEKISETAQQKNFSYKDDDRYEQASDVRAQLKFFEQLDQIEKQRKDEQ 918

  Fly   144 TG--FYRKRRAENIDEERKVARLE-----------------SVNDTALLAISGRKR-------PG 182
            ..  ..|..::.:..|:.:..||:                 ..|.|||.||..||:       ||
Mouse   919 EREILMRAAKSRSRQEDPEQLRLKQKAKEMQQQELAQMRQRDANLTALAAIGPRKKRKVDCTGPG 983

  Fly   183 ---EQLAPESA-PSGSKVAKLTGAPIQRACAPRFKHMNIRDVLQFMEEDRRYARSNMLFEAYLK 242
               |...|.:| |.||.|    |.| ::....|...:|:||::..:|.:|..:.|.:|::|:||
Mouse   984 SGAEGSGPGAAVPGGSGV----GTP-RQFTRQRITRVNLRDLIFCLENERETSHSLLLYKAFLK 1042

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nht	NP_523574.4	TAF4	10..238	CDD:173965	65/312 (21%)
Taf4	NP_001074561.1	TAFH	550..633	CDD:284862
Taf4	NP_001074561.1	TAF4	791..1039	CDD:283017	53/260 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2341
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001841
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR15138
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.910