Protein Alignment: CG15262 and CNOT2

• Sequence 1: NP_609750.1
• Gene: CG15262
• FlyBaseID: FBgn0028852
• Length: 438
• Species: Drosophila melanogaster
• Sequence 2: NP_001186231.1
• Gene: CNOT2
• HGNCID: 7878
• Length: 540
• Species: Homo sapiens
• Alignment Length: 449
• Identity: 99/450 (22%)
• Similarity: 164/450 (36%)
• Gaps: 174/450 (39%)

  Fly    11 DQQEVESSPSPPPPPPFQSPLSSPESLQTPDGYPILYVDVVKNKPKQELPPSASPSQPLAPEFSI 75
            |:...|.|.:|       :||.:|.:.:.|      ||.:|           ..|:...:.:|||
Human   235 DRNRREGSGNP-------TPLINPLAGRAP------YVGMV-----------TKPANEQSQDFSI 275

  Fly    76 FREDFPALPGS-----------LPSALPTALPTTSS---PVVPDDWTAMMSNSEQVELAKFRNTV 126
            ..|||||||||           ..|.|.|:..||||   |..|.|.::...|:.|
Human   276 HNEDFPALPGSSYKDPTSSNDDSKSNLNTSGKTTSSTDGPKFPGDKSSTTQNNNQ---------- 330

  Fly   127 IRNSSDPCVNANGNEVLRQPTHAPEKRQNMELLPHMYGYLGNPFRLNLSMIFTKQFLLEGVRQRA 191
                                     :::.:::||                        :|
Human   331 -------------------------QKKGIQVLP------------------------DG----- 341

  Fly   192 INAAHKRAALAKPAIQPPPGFENCKIFARLITNSDGMPLGGVTFELGSPTNETTSNVEAKPSGST 256
                                         .:||   :|.|.||.:
Human   342 -----------------------------RVTN---IPQGMVTDQ-------------------- 354

  Fly   257 IQGAFGMLGLAKKLRSINQNP----LLFGNNVAHNIG---GAADSI---FTGPIQEARLTPQEMS 311
                |||:||...:|:...:|    |..|:::. .:|   .:.:::   |..|...:...||::.
Human   355 ----FGMIGLLTFIRAAETDPGMVHLALGSDLT-TLGLNLNSPENLYPKFASPWASSPCRPQDID 414

  Fly   312 YKLPLNYLFNVNM--SLQEPKIEEMHDELLFFFFYTYAGDMMQMLAAAELAERGWRYHKYEHFWV 374
            :.:|..||.|:::  .|...|:....::|||:.:|...||::|:|||.||..|.|||||.|..|:
Human   415 FHVPSEYLTNIHIRDKLAAIKLGRYGEDLLFYLYYMNGGDVLQLLAAVELFNRDWRYHKEERVWI 479

  Fly   375 IRQADNPNYLYHGFREFGEYNYFNMWQWKILPRHFYLDPEILERTLSKEELYVTYGYHP 433
            .|.......:.....|.|.|.:|:...|:.:.:.|:|:.:.||   .:..|..|:.|:|
Human   480 TRAPGMEPTMKTNTYERGTYYFFDCLNWRKVAKEFHLEYDKLE---ERPHLPSTFNYNP 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15262	NP_609750.1	NOT2_3_5	294..414	CDD:282064	38/125 (30%)
CNOT2	NP_001186231.1	NOT2_3_5	396..519	CDD:335639	38/123 (31%)
		Repressor domain	437..540		34/103 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C224954056
eggNOG	1	0.900				E1_COG5601
Hieranoid	1	1.000
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950		0	Normalized mean entropy	S2523
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010				D1273874at2759
OrthoFinder	1	1.000				FOG0003118
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100			O	PTHR23326
Phylome	1	0.910		0.800	Consistency score
RoundUp	1	1.030		avgDist	Average_Evolutionary_Distance	R2209
TreeFam	1	0.960
User_Submission	0	0.000	Not matched by this tool.
	10	9.790