Protein Alignment CG15262 and ntl-2

DIOPT Version :8

• Sequence 1: NP_609750.1
• Gene: CG15262 / 34901
• FlyBaseID: FBgn0028852
• Length: 438
• Species: Drosophila melanogaster
• Sequence 2: NP_494772.1
• Gene: ntl-2 / 173773
• WormBaseID: WBGene00003825
• Length: 444
• Species: Caenorhabditis elegans
• Alignment Length: 399
• Identity: 88/400 (22%)
• Similarity: 148/400 (37%)
• Gaps: 140/400 (35%)

  Fly    48 VDVVKNKPKQELPPSASP-------SQP--LAPEFSIFREDFPALPGSLPSALPTALPTTSSPVV 103
            ::|.::.|.::|..:..|       |.|  ..|||.|..||||||||       .....|...::
 Worm    64 LNVAQSSPSRDLYGAQRPNYANLMRSDPSLTNPEFQIQNEDFPALPG-------VGSGQTQRSML 121

  Fly   104 PDDWTAMMSNSEQVELAKFRNTVIRNSSDPCVNANGNEVLRQPTHAPEKRQNMELLPHMYGYLG- 167
            .|....|:::..||:.|                                           |.||
 Worm   122 GDQLANMLADDHQVDFA-------------------------------------------GPLGD 143

  Fly   168 -NPFRLNLSMIFTKQFLLEGVRQRAINAAHKRAALAKPAIQPPPGFENCKIFARLITNSDGMPLG 231
             :|.||:            |:.:                                  ||...|:.
 Worm   144 CDPSRLS------------GISR----------------------------------NSQEGPMH 162

  Fly   232 GVTFELGSPTNETTSNVEAKPSGSTIQGAFGMLGLAKKLRSINQNPLLFGNNVAHNIGGAADSI- 295
            |:   :..|..|.| |:.|    |.:...|||.||...||::: ||.:....:.:::.....::
 Worm   163 GI---ITHPDGEVT-NIPA----SMLDDQFGMAGLVTYLRTVD-NPSIVSLALGYDLTTLGLNLN 218

  Fly   296 ---------FTGPIQEARLTPQEMSYKLPLNYLF--NVNMSLQEPKIEEMHDELLFFFFYTYAGD 349
                     |.||..::.:...|:..|:|..|:.  ::...|...::.::.:::||:.||....:
 Worm   219 LSERKLYMNFGGPWADSPIRAHELDVKVPEEYMTHNHIRDKLPPLRLNKVSEDVLFYLFYNCPNE 283

  Fly   350 MMQMLAAAELAERGWRYHKYEHFWVIR------QADNPNYLYHGFREFGEYNYFNMWQWKILPRH 408
            :.|:.||.||..|.||:||.|..|:.|      :....||      |.|.||.|:..||:.:|:.
 Worm   284 IYQVAAACELYAREWRFHKSEQVWLTRSQYGGVKEQTGNY------EKGHYNVFDQMQWRKIPKE 342

  Fly   409 FYLDPEILE 417
            ..|:.:.||
 Worm   343 LKLEYKELE 351

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15262	NP_609750.1	NOT2_3_5	294..414	CDD:282064	36/138 (26%)
ntl-2	NP_494772.1	NOT2_3_5	228..348	CDD:282064	36/126 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C224934583
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950		0	Normalized mean entropy	S2523
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010				D1273874at2759
OrthoFinder	1	1.000				FOG0003118
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100			O	PTHR23326
Phylome	1	0.910		0.833	Consistency score
RoundUp	1	1.030		avgDist	Average_Evolutionary_Distance	R2209
TreeFam	0	0.000	Not matched by this tool.
	8	7.930