Protein Alignment Pol32 and Pold3

DIOPT Version :9

• Sequence 1: NP_001188816.1
• Gene: Pol32 / 34892
• FlyBaseID: FBgn0283467
• Length: 431
• Species: Drosophila melanogaster
• Sequence 2: NP_001355309.1
• Gene: Pold3 / 67967
• MGIID: 1915217
• Length: 462
• Species: Mus musculus
• Alignment Length: 496
• Identity: 117/496 - (23%)
• Similarity: 195/496 - (39%)
• Gaps: 114/496 - (22%)

  Fly     7 LDDCMIDFDRCVLVTDLLEEYK-LSY------KEVNDVLEAYI---KEQEPATKFEKRFLVHGKR 61
            :|:.:.|.::.|       .|| |||      .:...:|..|:   :::....:....:||.|..
Mouse    10 IDEFVTDQNKIV-------TYKWLSYTLGVHVNQAKQMLYEYVERKRKENSGAQLHVTYLVSGSL 67

  Fly    62 KTQGSDSGEDLYSVVLESRMQDWLAKVQ-DAESQLYSVKIAGGTKAPAAIFKPMQHLEVKLAKVE 125
            ...|....:  .:||.|.:::...:|:. .|...:||::     ||......|:.:.:..:.| .
Mouse    68 IQNGHSCHK--VAVVREDKLEAVKSKLAVTASIHVYSIQ-----KAMLKDSGPLFNTDYDILK-S 124

  Fly   126 QRPGAGKI--------VPSANGTTPHNGVKSEPTKSEPSKSAVKLEPSKSSLKSE----PA-KSK 177
            ......|.        ||.|...:|.:      .|.|.|......|...|.|.:.    || |..
Mouse   125 NLQNCSKFSAIQCAAAVPRAPAESPSS------RKYEQSNLQAASEAQASELTTNGHGPPASKQA 183

  Fly   178 AEKP----------VASKSSPEDKKTSPKEQ----ASKAKPAAAKKGSI-NSFFTAAASKPKDVK 227
            :::|          .|:|:...:|:|.|:.:    ||.|...|..|||: ::||..||.....|
Mouse   184 SQQPKGIMGMLISKAATKTQDTNKETKPEAREVTSASSAGGKAPGKGSVMSNFFGKAAMNKLKV- 247

  Fly   228 ATPSKSTSGTVDNFFKKQPAGAKKS---PPESEDKSKKDASNSNKKEASKKKSPSPT--KKPTTA 287
                        |...:|....:|:   ||.|..:.|..|..:.|| :|:|..|...  |:.::.
Mouse   248 ------------NLDSEQAVKEEKTVEQPPVSVTEPKLAAPPAQKK-SSRKSEPGKVQQKEKSSR 299

  Fly   288 NTSMQLFDEESAESSDEEEKLDMLRRKVIESDNDSDQ--------EKASSSKRRRISDSED---- 340
            ...:.|.|||:.|:  |..|....|.|:.:||:..|:        .:|.|.....:|...|
Mouse   300 GKRVDLSDEEAKET--EHLKKKRRRIKLPQSDSSEDEVFEDSPEMYEADSPSPPPVSPPPDPMPK 362

  Fly   341 EEQPPKKSADEETIALDEKMDTEPANETYLDEDGFVITQR-----------KPTKAQPANKKVSP 394
            .|.||.|.:..||   ..:......::|::||:|.::|::           :..|.:||:....|
Mouse   363 TEPPPVKRSSGET---KRRRKRVLKSKTFVDEEGCIVTEKVYESESCTDSEEELKMKPASAHKPP 424

  Fly   395 KAAA---PVNKKKSPPSAAKA-GKDAPKTKQAGIMNFFSKK 431
            .||.   |..::|.|...|.| ||   ..:|..|..||.||
Mouse   425 AAAVKREPREERKGPKKGAAALGK---ANRQVSITGFFQKK 462

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pol32	NP_001188816.1	CDC27	<153..431	CDD:370537	84/329 (26%)
Pold3	NP_001355309.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	144..186		11/47 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	200..230		8/29 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	254..384		34/135 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	403..462		17/61 (28%)
		PIP-box. /evidence=ECO:0000250|UniProtKB:Q15054	452..459		2/6 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28HEU
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900