Protein Alignment CG4168 and Gp150

DIOPT Version :10

• Sequence 1: NP_609740.4
• Gene: CG4168 / 34889
• FlyBaseID: FBgn0028888
• Length: 1330
• Species: Drosophila melanogaster
• Sequence 2: XP_001688940.2
• Gene: Gp150 / 5667071
• VectorBaseID: AGAMI1_010005
• Length: 1116
• Species: Anopheles gambiae
• Alignment Length: 607
• Identity: 147/607 - (24%)
• Similarity: 267/607 - (43%)
• Gaps: 167/607 - (27%)

  Fly   341 RLDLGQNCIENLESDYFQQNYSDVHLRALNLEQNFVTQLPEAVFKATGIAHLV---LAFNAISRV 402
            |||        ||:..|..:.:|  |:.|::...:..:|....||..|::|:|   :....|..:
Mosquito   361 RLD--------LETQKFTSHITD--LQVLDVGPKYPIELGPEFFKKIGLSHVVSIKITNCTIVYI 415

  Fly   403 HPSAFEGLTETLEYLDLERNRLTTV-PVALSSLHHLKYLYLTSNQISQL----NNLP-------- 454
            .|.||.||.| |..::|..:.:..: |...::...|:.|.|:.|.:|.:    :|.|
Mosquito   416 SPQAFAGLDE-LYSVNLTNSGIDIIHPDTFANNTKLRLLTLSGNDLSAMQSVNHNTPYMDYMLKA 479

  Fly   455 -------------------SFTE--NLRVLSLSGNNFSMIPVLGLKNYTQLSYLNMGYNSITDIP 498
                               :|.|  |:..::||.||.|.:|.....|...:..|::..|:|.::|
Mosquito   480 PTVEELDISRCKLQELQPNAFNELKNIIYINLSENNLSNLPEGIFDNVETIEELDLSMNNIVELP 544

  Fly   499 EGIFAVDSWGSNLQTILLRNNKITHLHLGSFAGLE----QIQEISLSFNDI-TIHHPLVFENVSR 558
            :.|||..|    |..:.|::||||:       .::    .:|::.|||..| |:|:.:
Mosquito   545 KNIFAKTS----LAILHLKHNKITN-------NVDFVTADLQKLDLSFCQIRTVHNTM------- 591

  Fly   559 TLKILELSFAVFPARSLESLDPLDALLPLSQLIWLGLDNNNLKQVSNESFAQMRELSYINLSFNQ 623
                            .:.:|.|..|:         |..|:::::...:|..::.|.
Mosquito   592 ----------------FKGMDGLTNLI---------LKGNHIEKIKPMAFISLKNLR-------- 623

  Fly   624 LKTLPRGLFQSDAHSHLVEIDLSYNGLERLEAQTFHSLGDLQTLNLQSN-RLRTIARHAFHNLEF 687
                              :||||||.||::.||||.....|..:.|.:| ||:.:....|
Mosquito   624 ------------------QIDLSYNNLEQISAQTFIGNKMLDIIRLNNNPRLKRLPNEGF----- 665

  Fly   688 LRYLDLSYNRLVNISHGAFTVLPNLAALDLMHNQLCSLSLKSFLYVSNTTTPLRLNVSHNHI--- 749
                ::|:|       |.|||.    .:|:.:..:..|:..:|..:.:.|   |||::.|::
Mosquito   666 ----EISFN-------GTFTVY----FMDVSNCDISELADNTFKMMPHLT---RLNLAWNNLQTI 712

  Fly   750 -ASFYDELSSYMYIYQLDISHNHVTKSD--SFTNLANTLRFLNLAHNQLGSLQSHAFGDLEFLEI 811
             ::::..|:..|   .||:|:|.:...|  :|.|..| |..||||.||:.:|.|..|..|::|..
Mosquito   713 RSTYFAHLNKLM---DLDLSNNMIINMDEKTFQNNRN-LNTLNLAGNQIATLTSKLFHPLQYLSE 773

  Fly   812 LNVAHNNLTSLRRRSFQG------LNSLQELDLSHNQLDQLQVEQFSNLRKLRILRINSNRLRAL 870
            |:|:..:|.::...|..|      |.:|:.|::|:|::.::.|....::.|||:|.|.:|.|...
Mosquito   774 LDVSDCDLRTIWEDSAAGTKREEVLPNLKRLNVSYNEIMEVFVSDLESMGKLRVLDIRNNTLTCN 838

  Fly   871 PREVFMNTRLEFLDIAENQLSV 892
            .|   :.|.:::|.  :.|:|:
Mosquito   839 ER---LPTLIDWLQ--KKQISM 855

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4168	NP_609740.4	PRK15370	<69..>353	CDD:185268	3/11 (27%)
		leucine-rich repeat	99..118	CDD:275380
		leucine-rich repeat	122..146	CDD:275380
		leucine-rich repeat	147..170	CDD:275380
		leucine-rich repeat	171..194	CDD:275380
		leucine-rich repeat	195..214	CDD:275380
		leucine-rich repeat	215..236	CDD:275380
		leucine-rich repeat	266..287	CDD:275380
		leucine-rich repeat	288..311	CDD:275380
		leucine-rich repeat	312..338	CDD:275380
		LRR	<338..651	CDD:443914	76/351 (22%)
		leucine-rich repeat	339..365	CDD:275380	7/23 (30%)
		leucine-rich repeat	366..388	CDD:275380	5/21 (24%)
		leucine-rich repeat	389..412	CDD:275380	8/25 (32%)
		leucine-rich repeat	414..436	CDD:275380	3/22 (14%)
		leucine-rich repeat	437..459	CDD:275380	9/54 (17%)
		leucine-rich repeat	460..483	CDD:275380	7/22 (32%)
		leucine-rich repeat	484..510	CDD:275380	8/25 (32%)
		leucine-rich repeat	511..534	CDD:275380	6/26 (23%)
		leucine-rich repeat	535..589	CDD:275380	10/54 (19%)
		LRR	543..971	CDD:443914	87/364 (24%)
		leucine-rich repeat	590..613	CDD:275380	3/22 (14%)
		leucine-rich repeat	614..639	CDD:275380	1/24 (4%)
		leucine-rich repeat	640..663	CDD:275380	12/22 (55%)
		leucine-rich repeat	664..687	CDD:275380	6/23 (26%)
		leucine-rich repeat	688..711	CDD:275380	6/22 (27%)
		leucine-rich repeat	712..735	CDD:275380	3/22 (14%)
		leucine-rich repeat	740..783	CDD:275380	13/48 (27%)
		leucine-rich repeat	785..808	CDD:275380	11/22 (50%)
		leucine-rich repeat	809..832	CDD:275380	7/28 (25%)
		leucine-rich repeat	833..856	CDD:275380	5/22 (23%)
		leucine-rich repeat	857..879	CDD:275380	7/21 (33%)
		leucine-rich repeat	880..900	CDD:275380	3/13 (23%)
		leucine-rich repeat	905..928	CDD:275380
		LRR	911..>1203	CDD:443914
		leucine-rich repeat	929..952	CDD:275380
		leucine-rich repeat	953..977	CDD:275380
		leucine-rich repeat	978..1020	CDD:275380
		leucine-rich repeat	1045..1068	CDD:275380
		leucine-rich repeat	1069..1090	CDD:275380
		leucine-rich repeat	1091..1114	CDD:275380
		leucine-rich repeat	1115..1161	CDD:275380
		leucine-rich repeat	1162..1190	CDD:275380
		PCC	1230..>1298	CDD:188093
Gp150	XP_001688940.2	None