Protein Alignment CG4168 and tsku

DIOPT Version :10

• Sequence 1: NP_609740.4
• Gene: CG4168 / 34889
• FlyBaseID: FBgn0028888
• Length: 1330
• Species: Drosophila melanogaster
• Sequence 2: NP_001011330.1
• Gene: tsku / 496792
• XenbaseID: XB-GENE-493206
• Length: 350
• Species: Xenopus tropicalis
• Alignment Length: 318
• Identity: 86/318 - (27%)
• Similarity: 145/318 - (45%)
• Gaps: 55/318 - (17%)

  Fly   566 SFAVFPARSLESLDPLDA---LLPLSQLIWLGLDNNNLKQVSNESFAQMRELSYINLSFNQLKTL 627
            :|.:|.:.||..:|....   ::|:|    :.||.                 ||::||.|.:|.:
 Frog    31 NFGLFHSFSLTKVDCSGVGPHVVPVS----IPLDT-----------------SYLDLSANGIKRI 74

  Fly   628 PRGLFQSDAHSHLVEIDLSYNGLERLEAQTFHSLGDLQTLNLQSNRLRTIARHAFHNLEFLRYLD 692
            ...:.....::.|:.::||:|.:.|:...||..|..|::|:|..|.|.|:...:| ....|..||
 Frog    75 NESVLSGPGYTTLINLNLSHNQIVRISFSTFSKLRYLESLDLSHNLLETLPDGSF-LYSRLTELD 138

  Fly   693 LSYNRLVNISHGAFTVLPNLAALDLMHNQLCSLSLKSFLYVSNTTTPLRLNVSHNHIASFYDELS 757
            ||.|:|:.:..||||                   |||      ....:.:|:.:|:|.|.:....
 Frog   139 LSSNKLLEVGIGAFT-------------------LKS------QGRSMTINLGNNNIRSIHRGAE 178

  Fly   758 SYM-YIYQLDISHNHVTKSDSFTNLANTLRFLNLAHNQLGSLQSHAFGDLEFLEILNVAH-NNLT 820
            ..: .|:.|.:|.|.:........:  .||.|:|..|.|..::..:|..||.|..|:::. .||.
 Frog   179 RPVPNIHSLTLSGNDLLSVPDLHGI--PLRHLDLDRNPLAKIEKESFLGLEGLTHLSLSDLPNLR 241

  Fly   821 SLRRRSFQGLNSLQELDLSHN-QLDQLQVEQFSNLRKLRILRINSNRLRALPREVFMN 877
            .:...||:.|.||.:||||.| ||..|..:.|..|..|:.|.:..:.:.|||:::.:|
 Frog   242 EVSPYSFKTLPSLLDLDLSSNPQLKSLSSDMFFGLDSLQELNLAYSGVAALPKDIMLN 299

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4168	NP_609740.4	PRK15370	<69..>353	CDD:185268
		leucine-rich repeat	99..118	CDD:275380
		leucine-rich repeat	122..146	CDD:275380
		leucine-rich repeat	147..170	CDD:275380
		leucine-rich repeat	171..194	CDD:275380
		leucine-rich repeat	195..214	CDD:275380
		leucine-rich repeat	215..236	CDD:275380
		leucine-rich repeat	266..287	CDD:275380
		leucine-rich repeat	288..311	CDD:275380
		leucine-rich repeat	312..338	CDD:275380
		LRR	<338..651	CDD:443914	19/87 (22%)
		leucine-rich repeat	339..365	CDD:275380
		leucine-rich repeat	366..388	CDD:275380
		leucine-rich repeat	389..412	CDD:275380
		leucine-rich repeat	414..436	CDD:275380
		leucine-rich repeat	437..459	CDD:275380
		leucine-rich repeat	460..483	CDD:275380
		leucine-rich repeat	484..510	CDD:275380
		leucine-rich repeat	511..534	CDD:275380
		leucine-rich repeat	535..589	CDD:275380	6/25 (24%)
		LRR	543..971	CDD:443914	86/318 (27%)
		leucine-rich repeat	590..613	CDD:275380	2/22 (9%)
		leucine-rich repeat	614..639	CDD:275380	6/24 (25%)
		leucine-rich repeat	640..663	CDD:275380	8/22 (36%)
		leucine-rich repeat	664..687	CDD:275380	7/22 (32%)
		leucine-rich repeat	688..711	CDD:275380	11/22 (50%)
		leucine-rich repeat	712..735	CDD:275380	3/22 (14%)
		leucine-rich repeat	740..783	CDD:275380	8/43 (19%)
		leucine-rich repeat	785..808	CDD:275380	8/22 (36%)
		leucine-rich repeat	809..832	CDD:275380	7/23 (30%)
		leucine-rich repeat	833..856	CDD:275380	11/23 (48%)
		leucine-rich repeat	857..879	CDD:275380	6/21 (29%)
		leucine-rich repeat	880..900	CDD:275380
		leucine-rich repeat	905..928	CDD:275380
		LRR	911..>1203	CDD:443914
		leucine-rich repeat	929..952	CDD:275380
		leucine-rich repeat	953..977	CDD:275380
		leucine-rich repeat	978..1020	CDD:275380
		leucine-rich repeat	1045..1068	CDD:275380
		leucine-rich repeat	1069..1090	CDD:275380
		leucine-rich repeat	1091..1114	CDD:275380
		leucine-rich repeat	1115..1161	CDD:275380
		leucine-rich repeat	1162..1190	CDD:275380
		PCC	1230..>1298	CDD:188093
tsku	NP_001011330.1	LRRNT	21..63	CDD:214470	9/52 (17%)
		LRR 1	60..81		7/37 (19%)
		leucine-rich repeat	61..86	CDD:275380	6/41 (15%)
		LRR	<62..>236	CDD:443914	54/201 (27%)
		LRR 2	86..107		7/20 (35%)
		leucine-rich repeat	87..110	CDD:275380	8/22 (36%)
		LRR 3	110..131		7/21 (33%)
		leucine-rich repeat	111..133	CDD:275380	7/22 (32%)
		LRR 4	133..154		11/39 (28%)
		leucine-rich repeat	134..159	CDD:275380	14/49 (29%)
		LRR 5	159..180		4/20 (20%)
		leucine-rich repeat	160..183	CDD:275380	4/22 (18%)
		LRR 6	183..203		4/19 (21%)
		leucine-rich repeat	184..203	CDD:275380	4/18 (22%)
		LRR 7	204..225		7/20 (35%)
		LRR_8	205..286	CDD:404697	30/80 (38%)
		leucine-rich repeat	205..228	CDD:275380	8/22 (36%)
		LRR 8	228..250		6/21 (29%)
		leucine-rich repeat	229..278	CDD:275380	19/48 (40%)
		LRR 9	253..275		11/21 (52%)
		LRR 10	278..299		5/20 (25%)
		leucine-rich repeat	279..302	CDD:275380	6/21 (29%)