Protein Alignment CG4168 and tsku

DIOPT Version :10

• Sequence 1: NP_609740.4
• Gene: CG4168 / 34889
• FlyBaseID: FBgn0028888
• Length: 1330
• Species: Drosophila melanogaster
• Sequence 2: NP_956027.2
• Gene: tsku / 325958
• ZFINID: ZDB-GENE-030131-4683
• Length: 366
• Species: Danio rerio
• Alignment Length: 320
• Identity: 89/320 - (27%)
• Similarity: 145/320 - (45%)
• Gaps: 61/320 - (19%)

  Fly   566 SFAVFPARSLESLD-----PLDALLPLSQLIWLGLDNNNLKQVSNESFAQMRELSYINLSFNQLK 625
            :|.:|.:.||..:|     |.:..:|:.      ||.                 |:::||.|.:.
Zfish    52 TFGLFDSFSLTKVDCSRIGPGNTPVPIP------LDT-----------------SHLDLSLNSIT 93

  Fly   626 TLPRGLFQSDAHSHLVEIDLSYNGLERLEAQTFHSLGDLQTLNLQSNRLRTIARHAFHNLEFLRY 690
            ::...:.....::.||.:|||                        ||.:..|:..||..|.:|..
Zfish    94 SISDTMLSGPGYTTLVSLDLS------------------------SNLIAQISPKAFSKLRYLET 134

  Fly   691 LDLSYNRLVNISHGAFTVLPNLAALDLMHNQLCSLSLKSFLYVSNT-TTPLRLNVSHNHIASFYD 754
            ||||.|.|..:|.|.||.|| |..|||..||....:|.  |:.:.| ..|:.:::|.|.:.|.:.
Zfish   135 LDLSSNALEGLSDGCFTGLP-LVELDLSENQFKEFNLD--LFTTRTQDLPIMVDLSRNLLTSIFR 196

  Fly   755 ELSSY-MYIYQLDISHNHVTKSDSFTNLANTLRFLNLAHNQLGSLQSHAFGDLEFLEILNVAH-N 817
            ....: :||..|.::.|.:........:  .|::|||..|.:.|:.:.||..|..|..|:::. :
Zfish   197 RTPGHPLYIKSLMLAGNQLKTVPKLNGI--PLQYLNLDGNLISSIDTGAFDSLTELVHLSLSGLS 259

  Fly   818 NLTSLRRRSFQGLNSLQELDLSHN-QLDQLQVEQFSNLRKLRILRINSNRLRALPREVFM 876
            .||.:...:|:.|.:||.||||:| ||..|..:.||.|..|:.|.:::..:..|.|.|||
Zfish   260 ELTLIHPGAFRSLKNLQALDLSNNSQLKTLNPDVFSGLVSLQELNLSNTAVTPLSRTVFM 319

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4168	NP_609740.4	PRK15370	<69..>353	CDD:185268
		leucine-rich repeat	99..118	CDD:275380
		leucine-rich repeat	122..146	CDD:275380
		leucine-rich repeat	147..170	CDD:275380
		leucine-rich repeat	171..194	CDD:275380
		leucine-rich repeat	195..214	CDD:275380
		leucine-rich repeat	215..236	CDD:275380
		leucine-rich repeat	266..287	CDD:275380
		leucine-rich repeat	288..311	CDD:275380
		leucine-rich repeat	312..338	CDD:275380
		LRR	<338..651	CDD:443914	18/89 (20%)
		leucine-rich repeat	339..365	CDD:275380
		leucine-rich repeat	366..388	CDD:275380
		leucine-rich repeat	389..412	CDD:275380
		leucine-rich repeat	414..436	CDD:275380
		leucine-rich repeat	437..459	CDD:275380
		leucine-rich repeat	460..483	CDD:275380
		leucine-rich repeat	484..510	CDD:275380
		leucine-rich repeat	511..534	CDD:275380
		leucine-rich repeat	535..589	CDD:275380	7/27 (26%)
		LRR	543..971	CDD:443914	89/320 (28%)
		leucine-rich repeat	590..613	CDD:275380	2/22 (9%)
		leucine-rich repeat	614..639	CDD:275380	4/24 (17%)
		leucine-rich repeat	640..663	CDD:275380	5/22 (23%)
		leucine-rich repeat	664..687	CDD:275380	6/22 (27%)
		leucine-rich repeat	688..711	CDD:275380	12/22 (55%)
		leucine-rich repeat	712..735	CDD:275380	8/22 (36%)
		leucine-rich repeat	740..783	CDD:275380	7/43 (16%)
		leucine-rich repeat	785..808	CDD:275380	9/22 (41%)
		leucine-rich repeat	809..832	CDD:275380	6/23 (26%)
		leucine-rich repeat	833..856	CDD:275380	13/23 (57%)
		leucine-rich repeat	857..879	CDD:275380	7/20 (35%)
		leucine-rich repeat	880..900	CDD:275380
		leucine-rich repeat	905..928	CDD:275380
		LRR	911..>1203	CDD:443914
		leucine-rich repeat	929..952	CDD:275380
		leucine-rich repeat	953..977	CDD:275380
		leucine-rich repeat	978..1020	CDD:275380
		leucine-rich repeat	1045..1068	CDD:275380
		leucine-rich repeat	1069..1090	CDD:275380
		leucine-rich repeat	1091..1114	CDD:275380
		leucine-rich repeat	1115..1161	CDD:275380
		leucine-rich repeat	1162..1190	CDD:275380
		PCC	1230..>1298	CDD:188093
tsku	NP_956027.2	leucine-rich repeat	82..107	CDD:275380	4/41 (10%)
		LRR	<106..>314	CDD:443914	71/236 (30%)
		leucine-rich repeat	108..131	CDD:275380	11/46 (24%)
		leucine-rich repeat	132..153	CDD:275380	11/20 (55%)
		leucine-rich repeat	155..176	CDD:275380	8/22 (36%)
		leucine-rich repeat	177..220	CDD:275380	9/42 (21%)
		leucine-rich repeat	226..249	CDD:275380	9/22 (41%)
		leucine-rich repeat	250..274	CDD:275380	6/23 (26%)
		leucine-rich repeat	275..299	CDD:275380	13/23 (57%)
		leucine-rich repeat	300..323	CDD:275380	7/20 (35%)