Protein Alignment CG4168 and igfals

DIOPT Version :10

• Sequence 1: NP_609740.4
• Gene: CG4168 / 34889
• FlyBaseID: FBgn0028888
• Length: 1330
• Species: Drosophila melanogaster
• Sequence 2: XP_002940278.2
• Gene: igfals / 100489984
• XenbaseID: XB-GENE-1008441
• Length: 601
• Species: Xenopus tropicalis
• Alignment Length: 527
• Identity: 152/527 - (28%)
• Similarity: 246/527 - (46%)
• Gaps: 74/527 - (14%)

  Fly   586 PLSQLIWLGLDNNNLKQVSNESFAQMRELSYINLSFNQLKTLPR----GLFQSDAHSH------- 639
            |.::.:|  ||.|||..|...:|..:..|.::||..:|:.:|.:    || ::.||.|
 Frog    67 PAARSLW--LDGNNLTTVQAGAFRNLSHLDFLNLQSSQVASLEQQALHGL-KALAHLHLERNMIK 128

  Fly   640 ------------LVEIDLSYNGLERLEAQTFHSLGDLQTLNLQSNRLRTIARHAFHNLEFLRYLD 692
                        ||.:.|:.|.|.::|...|..|.:|..|||..|.|..:....||:|..||.|.
 Frog   129 SLAPSTFTHTQNLVSLTLNNNFLTKIEDGLFSGLSNLWYLNLGWNLLVVLPDMVFHDLLNLRELV 193

  Fly   693 LSYNRLVNISHGAFTVLPNLAALDLMHNQLCSLSLKSFLYVSNTTTPLRLNVSHNHIASFYDELS 757
            |:.||||.:....|..|..|..|||..|.|..:....|.....|.   :|.::||||::......
 Frog   194 LAGNRLVYLQPSLFLSLGELKELDLSGNSLKGIKANVFTRQQKTH---KLYLNHNHISTVAPRAF 255

  Fly   758 SYM-YIYQLDISHNHVTK--SDSFTNLANTLRFLNLAHNQLGSLQSHAFGDLEFLEILNVAHNNL 819
            |.| .:..||:|||.:|.  .|:|..|. :|..|.|::|.|.||:...|.||:||..||:..|.:
 Frog   256 SGMKNLRWLDLSHNRLTALYEDTFFGLP-SLNVLRLSNNSLTSLRPRIFKDLQFLVELNLGQNKI 319

  Fly   820 TSLRRRSFQGLNSLQELDLSHNQLDQLQVEQFSNLRKLRILRINSNRLRALPREVFMNT-RLEFL 883
            ..|..|:|:||..|:.|.|:||.:.:::...|..|..:.::.::.|.|::|....|... :|..|
 Frog   320 KILLERTFEGLAQLELLSLNHNNVQEIRPGSFLGLLNVAVINLSGNCLKSLAEHCFKGLGKLHSL 384

  Fly   884 DIAENQLSVWPVPAFTDIGFTLRSIQMSHNNLEYLDASMFINSQFLYDISLARNRITILPDNTFS 948
            .:..:.||......|..:. ::|.:.:.:|.:..::...|.:...|.::.|..|::|.|...:|:
 Frog   385 HMESSCLSHIKPQMFAGLS-SIRRLFLQNNEIVAIEDHSFTDLHGLLELDLRSNKLTHLTTRSFT 448

  Fly   949 FLNNLTNLDLSQNPLVTTNLREVFVHTPRLRKLSLHHMGLYVLPPLKLPLLSYLDVSGNYLQELS 1013
            .|.||:.|.||.|.::|.: .|||....:|:                     :||:|.|.|:.|:
 Frog   449 GLKNLSYLLLSSNQILTIS-PEVFSPVQQLQ---------------------WLDLSDNQLKALT 491

  Fly  1014 -----PLGSLRHLRHVNVSHNKLTNASCAAEHLPPSVRVLDLAHNP---------LRRITLHDLA 1064
                 ||.|||:|   ::.:|.|...|......||:::.|.|..|.         ||.:.|.:..
 Frog   492 EDIFLPLSSLRYL---SLKNNCLKTISVNFLIPPPTMQQLWLNGNQWDCGCALKGLRDLALRNST 553

  Fly  1065 SLRHLAE 1071
            .:.||.:
 Frog   554 IVPHLVQ 560

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4168	NP_609740.4	PRK15370	<69..>353	CDD:185268
		leucine-rich repeat	99..118	CDD:275380
		leucine-rich repeat	122..146	CDD:275380
		leucine-rich repeat	147..170	CDD:275380
		leucine-rich repeat	171..194	CDD:275380
		leucine-rich repeat	195..214	CDD:275380
		leucine-rich repeat	215..236	CDD:275380
		leucine-rich repeat	266..287	CDD:275380
		leucine-rich repeat	288..311	CDD:275380
		leucine-rich repeat	312..338	CDD:275380
		LRR	<338..651	CDD:443914	23/87 (26%)
		leucine-rich repeat	339..365	CDD:275380
		leucine-rich repeat	366..388	CDD:275380
		leucine-rich repeat	389..412	CDD:275380
		leucine-rich repeat	414..436	CDD:275380
		leucine-rich repeat	437..459	CDD:275380
		leucine-rich repeat	460..483	CDD:275380
		leucine-rich repeat	484..510	CDD:275380
		leucine-rich repeat	511..534	CDD:275380
		leucine-rich repeat	535..589	CDD:275380	1/2 (50%)
		LRR	543..971	CDD:443914	123/411 (30%)
		leucine-rich repeat	590..613	CDD:275380	8/22 (36%)
		leucine-rich repeat	614..639	CDD:275380	9/28 (32%)
		leucine-rich repeat	640..663	CDD:275380	8/22 (36%)
		leucine-rich repeat	664..687	CDD:275380	9/22 (41%)
		leucine-rich repeat	688..711	CDD:275380	10/22 (45%)
		leucine-rich repeat	712..735	CDD:275380	7/22 (32%)
		leucine-rich repeat	740..783	CDD:275380	16/45 (36%)
		leucine-rich repeat	785..808	CDD:275380	10/22 (45%)
		leucine-rich repeat	809..832	CDD:275380	9/22 (41%)
		leucine-rich repeat	833..856	CDD:275380	7/22 (32%)
		leucine-rich repeat	857..879	CDD:275380	4/22 (18%)
		leucine-rich repeat	880..900	CDD:275380	5/19 (26%)
		leucine-rich repeat	905..928	CDD:275380	3/22 (14%)
		LRR	911..>1203	CDD:443914	45/175 (26%)
		leucine-rich repeat	929..952	CDD:275380	7/22 (32%)
		leucine-rich repeat	953..977	CDD:275380	9/23 (39%)
		leucine-rich repeat	978..1020	CDD:275380	11/46 (24%)
		leucine-rich repeat	1045..1068	CDD:275380	6/31 (19%)
		leucine-rich repeat	1069..1090	CDD:275380	1/3 (33%)
		leucine-rich repeat	1091..1114	CDD:275380
		leucine-rich repeat	1115..1161	CDD:275380
		leucine-rich repeat	1162..1190	CDD:275380
		PCC	1230..>1298	CDD:188093
igfals	XP_002940278.2	leucine-rich repeat	69..92	CDD:275380	8/24 (33%)
		PLN00113	71..>534	CDD:215061	145/495 (29%)
		leucine-rich repeat	93..116	CDD:275380	7/23 (30%)
		leucine-rich repeat	117..140	CDD:275380	3/22 (14%)
		leucine-rich repeat	141..164	CDD:275380	8/22 (36%)
		leucine-rich repeat	165..188	CDD:275380	9/22 (41%)
		leucine-rich repeat	189..212	CDD:275380	10/22 (45%)
		leucine-rich repeat	213..236	CDD:275380	7/22 (32%)
		leucine-rich repeat	237..260	CDD:275380	8/25 (32%)
		leucine-rich repeat	261..284	CDD:275380	9/23 (39%)
		leucine-rich repeat	285..308	CDD:275380	10/22 (45%)
		leucine-rich repeat	309..332	CDD:275380	9/22 (41%)
		leucine-rich repeat	333..354	CDD:275380	6/20 (30%)
		leucine-rich repeat	357..380	CDD:275380	4/22 (18%)
		leucine-rich repeat	381..404	CDD:275380	5/23 (22%)
		leucine-rich repeat	405..428	CDD:275380	3/22 (14%)
		leucine-rich repeat	429..450	CDD:275380	6/20 (30%)
		leucine-rich repeat	453..472	CDD:275380	8/19 (42%)
		leucine-rich repeat	477..500	CDD:275380	9/43 (21%)
		leucine-rich repeat	525..537	CDD:275378	3/11 (27%)