DRSC/TRiP Functional Genomics Resources

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Protein Alignment stc and FAP1

DIOPT Version :10

Sequence 1:NP_476599.1 Gene:stc / 34888 FlyBaseID:FBgn0001978 Length:1106 Species:Drosophila melanogaster
Sequence 2:NP_014375.1 Gene:FAP1 / 855708 SGDID:S000004968 Length:965 Species:Saccharomyces cerevisiae


Alignment Length:848 Identity:250/848 - (29%)
Similarity:369/848 - (43%) Gaps:161/848 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly   310 NKRRDDWNRNRDRINGFPRAVDDLDTSNESAHPSP-EKQSQLQQISPRRGPPLPPADNEKLSQRE 373
            |:...|..|:.:..:|...:|:|   :||  .||. |::|                 ::.:...|
Yeast    12 NQDGGDTYRHHNLSDGCISSVED---ANE--QPSSYEEES-----------------DDDMQYYE 54

  Fly   374 KLVRDIEQ-RRLECLVCVEAIKSHQPTWSCRNCYHMLHLKCTITWASSSKSEVG---WRCPACQN 434
            :.:::|.. ....|::|...:......::|:.||.:....|...||..|..:..   |:||.|..
Yeast    55 RAIQEISSGDSYVCMICTVEMDYTCQMFACKRCYRVFDYGCIREWALKSTEKTVDRIWKCPNCYY 119

  Fly   435 VLQDLP--RDYLCFCGKLKNPPVSRTELAHSCGEVCCRIEGCSHACTLLCHPGPCPPCQANVVRS 497
            |.:.:|  ....|:|||:.||..:..: .:|||:. |....|.|.|:.:||.||.|.|...|...
Yeast   120 VSKRVPVKNRPTCWCGKVVNPDPNPLD-PNSCGQT-CNASTCMHGCSKICHLGPHPECTRMVEIM 182

  Fly   498 CGCGRSTKTMQC----AMKEEVLCGEICDKLLNCGEHRCQAECHSGKCAACSEQVVQ-------- 550
            |.||:.:|::.|    .||:...|.|:|...|:|..|.|:.:||.|.|..|.|.::.        
Yeast   183 CHCGKHSKSIFCYQSKVMKKNFNCQEVCGLPLSCSIHTCKKKCHPGLCGPCPEMIISKDSPKKQI 247

  Fly   551 QCHCGKQER-KVPCT--------RESQDKR------TYSCKDSCGQPLPCGHHKCKDSCHA---- 596
            :|:||...| .:.|:        :.|:|:.      .::|.|:......|..|...:||.:    
Yeast   248 KCYCGNHTRANIKCSETKFPKSGKSSKDENGNRWIGVFACADNRVVDYSCRKHSFIESCISPPTI 312

  Fly   597 GSCRPCKLSPEQITSCPCGKMPVP--AGQRSSCLDPIPTCEGICSRTLRCGKPAHPHQCGSKCHL 659
            ...:.|...|..:.:||||:..:.  ...|..|.||||||:..|.:.|:|||    |.|...||.
Yeast   313 NGEKACPFLPSSLKTCPCGRTALEELTKPRKHCDDPIPTCDSRCGKPLKCGK----HSCPFTCHD 373

  Fly   660 GQC-PPCPKQTGVKCRCGHMDQMIKCRQLCNRADDARCKRRCTKKRSCGKHKCNVECC------- 716
            ..| .||.:...|||.|......:.    |......||..:|....||.:|:|...||       
Yeast   374 KACMEPCLQIDSVKCACEQSTFSVP----CGFQGRPRCNIKCESLMSCRRHRCTDRCCSGRPSAI 434

  Fly   717 -----------------IDIDHDCPLPCNRTLSCGKHKCDQPCHRGNCPPCYRSSFEELYCECGA 764
                             ::..|.|..|||.|||||.|||.:.||.|.||||..|...:|.|.||.
Yeast   435 RRKKNLFRTQDLLDESLVEAKHICLKPCNLTLSCGIHKCQRKCHPGKCPPCLESDSNDLVCPCGN 499

  Fly   765 EVIYPPVPCGTKKPICKLPCSRI----HPCDHPPQ-HNCHS-GPTCPPCMIFTTKLCHGNHELRK 823
            .|:..||.||||.|.|..||.::    ..|.|.|. |.||| ..:||||.....|.|....:.:.
Yeast   500 TVVPAPVRCGTKLPTCNHPCIKVVRGESTCGHKPMPHTCHSLDVSCPPCTETVFKPCKCGKKTKV 564

  Fly   824 TIPCSQPNFSCGMACGKPLPCGGHKCIKPCH-EGPCQSAGEICRQSCTKPRPTCGHKCAAACH-E 886
            ...|.|.:.|||:.||.||....|.|.|.|| .|.||   ::|:|:|.:.|..|.|:|...|| :
Yeast   565 RTVCFQTDVSCGIKCGIPLSYCYHTCQKTCHLPGNCQ---KVCKQTCGQKRLNCNHECPKPCHGK 626

  Fly   887 GACPETPCKELVEVQCECGNRKQNRSCQELAREHSRIATIQLASSMAEMSRGNYMELSEILAPAK 951
            ..||:.||..||::.|:||..|::.:|   ..:..|:       |:.|.|               
Yeast   627 TECPDLPCATLVKIYCKCGRIKKSVTC---GAKSDRV-------SVTESS--------------- 666

  Fly   952 KSNKTLDCNDECRLLERNRRLAAA---------LSSGNSDTKQKCL---TKYSEFVRGFAKKNPA 1004
                .||||:||..|:|.:.|..|         .:|...|..:|.:   |.:.|....|.:  .|
Yeast   667 ----VLDCNEECEALKRLKELKEAFGIKEETNNFTSNELDALKKLVSVATTFEELQLPFTE--AA 725

  Fly  1005 LTKSVY-------ETLTDLVKLAKESKQRSRSHSFPTMNREKRQLVHELCEVFGIESVSYDKEPN 1062
            |  |||       ..:..::....:.|.||..| |..|...:|..:.||.:.:|:.|.|.|:||.
Yeast   726 L--SVYSKQERWCSQIEAILNKLMDDKTRSSLH-FKPMRPPQRHFIRELAKAYGLYSESQDREPM 787

  Fly  1063 RNV 1065
            |:|
Yeast   788 RSV 790

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
stcNP_476599.1 RING_Ubox 385..433 CDD:473075 12/50 (24%)
NF-X1-zinc-finger 464..510 CDD:100116 18/49 (37%)
NF-X1-zinc-finger 517..565 CDD:100116 18/64 (28%)
NF-X1-zinc-finger 575..617 CDD:100116 12/45 (27%)
NF-X1-zinc-finger 634..686 CDD:100116 17/52 (33%)
NF-X1-zinc-finger 723..775 CDD:100116 28/51 (55%)
NF-X1-zinc-finger 834..882 CDD:100116 21/48 (44%)
NF-X1-zinc-finger 865..915 CDD:100116 20/50 (40%)
R3H_NF-X1 996..1069 CDD:100072 23/77 (30%)
FAP1NP_014375.1 RING-CH-C4HC3_NFX1-like 66..118 CDD:438155 12/51 (24%)
NF-X1-zinc-finger 150..196 CDD:100116 18/46 (39%)
NF-X1-zinc-finger 206..263 CDD:100116 18/56 (32%)
NF-X1-zinc-finger 352..400 CDD:100116 17/55 (31%)
NF-X1-zinc-finger 458..505 CDD:100116 25/46 (54%)
NF-X1-zinc-finger 604..655 CDD:100116 20/53 (38%)
R3H_unknown_2 736..794 CDD:100076 17/56 (30%)

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