Protein Alignment THG and thg1

DIOPT Version :10

• Sequence 1: NP_609737.1
• Gene: THG / 34876
• FlyBaseID: FBgn0283659
• Length: 286
• Species: Drosophila melanogaster
• Sequence 2: NP_587981.1
• Gene: thg1 / 2539571
• PomBaseID: SPCC63.07
• Length: 261
• Species: Schizosaccharomyces pombe
• Alignment Length: 259
• Identity: 140/259 - (54%)
• Similarity: 180/259 - (69%)
• Gaps: 13/259 - (5%)

  Fly     1 MACSRFEYVKSFEQDDSILPNVWIVIRIDGKKFHKFSKTHDFEKPNDENALNVMNAAATAVMQEF 65
            ||.|||||||.:|:.|.:||..:||||||||.||||:|.||||||||...||:|||||..||.||
pombe     1 MAKSRFEYVKQYERLDRLLPETYIVIRIDGKGFHKFTKKHDFEKPNDLRCLNLMNAAARVVMSEF 65

  Fly    66 RDIVLAYGQSDEYSFVFRKETAAFKRRSAKLLTYVTSLFSSSYVMQWSKWMNLPLAYAPCFDGRV 130
            .|||||||.|||||||:.|.|..::||.:||:::|.|||:|::|..|.|..::||...|.||||.
pombe    66 TDIVLAYGDSDEYSFVWSKSTELYERRESKLVSHVCSLFTSAFVFNWPKHFDIPLLSLPSFDGRA 130

  Fly   131 VLYPSEQNLKDYLSWRQADVHVNNLYNTAFWKLVLEKGLTNQQAEAKLRGTFSADKNELLFQEFG 195
            ||||:.:.|:|||.|||.|.|:||||||.||.|:|:.|.||.|||..|:||.||:|:|:||.:||
pombe   131 VLYPNMKVLRDYLHWRQVDCHINNLYNTTFWMLILKGGFTNTQAEEYLKGTVSAEKHEILFSKFG 195

  Fly   196 INYNNLPAMYRKGTILLR-----------KRVILGEKSRQAVVPLHEDLISSQFW--KEHTEIL 246
            ||||..|.:|:||:|.:|           |:..:.:|.:..:..||..||...||  :...|:|
pombe   196 INYNFEPEIYKKGSIWIREPIDQEWHQQDKKFSVKQKKKMVLSILHVSLIDDDFWTSRPFLEVL 259

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
THG	NP_609737.1	Thg1	6..134	CDD:461314	78/127 (61%)
		Thg1C	137..234	CDD:464167	50/107 (47%)
thg1	NP_587981.1	Thg1	6..134	CDD:461314	78/127 (61%)
		Thg1C	137..>217	CDD:464167	46/79 (58%)