DRSC/TRiP Functional Genomics Resources

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Protein Alignment THG and THG

DIOPT Version :10

Sequence 1:NP_609737.1 Gene:THG / 34876 FlyBaseID:FBgn0283659 Length:286 Species:Drosophila melanogaster
Sequence 2:XP_320758.5 Gene:THG / 1280888 VectorBaseID:AGAMI1_012026 Length:323 Species:Anopheles gambiae


Alignment Length:297 Identity:159/297 - (53%)
Similarity:204/297 - (68%) Gaps:13/297 - (4%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MACSRFEYVKSFEQDDSILPNVWIVIRIDGKKFHKFSKTHDFEKPNDENALNVMNAAATAVMQEF 65
            ||.|||||||.|||::.:|||.|||:|||||.||:|...|.|.||||.:||.:||.|...|:|||
Mosquito    25 MALSRFEYVKQFEQEEKLLPNSWIVVRIDGKGFHRFCNVHSFSKPNDLDALQLMNLAGMTVLQEF 89

  Fly    66 RDIVLAYGQSDEYSFVFRKETAAFKRRSAKLLTYVTSLFSSSYVMQWSK---WMNLPLAYAPCFD 127
            .:|.:.||||||||||||:|.:.::||..||::||.|||:|:|:..|.:   ..::.:.|.|.||
Mosquito    90 NEIAIGYGQSDEYSFVFRREASVYQRRRDKLVSYVASLFTSAYMFHWKRIFDGRSIAMRYPPSFD 154

  Fly   128 GRVVLYPSEQNLKDYLSWRQADVHVNNLYNTAFWKLVLEKGLTNQQAEAKLRGTFSADKNELLFQ 192
            .|.||||:::||:||||||||||||||||||.||.|| ..||:|..||.:|:||.::||||:||.
Mosquito   155 ARAVLYPTDENLRDYLSWRQADVHVNNLYNTTFWNLV-ASGLSNSDAEKRLQGTLASDKNEILFS 218

  Fly   193 EFGINYNNLPAMYRKGTILLRKRVILGE-KSRQAVVPLHEDLISSQFWKEHTEILGK-------Y 249
            :|||||||.|.:||||||||.|.|:..| |.::.:||:.|||||..||.:|.|||.|       |
Mosquito   219 QFGINYNNEPVIYRKGTILLPKSVVSSEGKKQRLIVPIFEDLISDAFWAKHPEILDKKAKTDELY 283

  Fly   250 VPGTYDAPQTFPRLVEMQINGKDD-NEAEEPQNLAGT 285
            ..|..:|.......:|:|...|.. |:||....|..|
Mosquito   284 DLGENEAQPVVRYQLEVQERRKAGMNKAETGNRLLAT 320

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
THGNP_609737.1 Thg1 6..134 CDD:461314 70/130 (54%)
Thg1C 137..234 CDD:464167 62/97 (64%)
THGXP_320758.5 None

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