Protein Alignment Ankrd49 and ANKRD49

DIOPT Version :10

• Sequence 1: NP_609735.1
• Gene: Ankrd49 / 34874
• FlyBaseID: FBgn0261881
• Length: 215
• Species: Drosophila melanogaster
• Sequence 2: NP_060174.2
• Gene: ANKRD49 / 54851
• HGNCID: 25970
• Length: 239
• Species: Homo sapiens
• Alignment Length: 212
• Identity: 86/212 - (40%)
• Similarity: 126/212 - (59%)
• Gaps: 18/212 - (8%)

  Fly     5 DSDDEKSQVEKLR-HAK-VPRG---MFVSGWDDDADELIEEDKNP----------QSSIERMILW 54
            |..:..:|:|.|. |.. :|.|   ::|...|:|.:   ::|||.          :....|::||
Human    19 DFSEHFNQLELLETHGHLIPTGTQSLWVGNSDEDEE---QDDKNEEWYRLQEKKMEKDPSRLLLW 80

  Fly    55 AVNENRISEVREILKLDADTVNAKDNDGYTPLHRAAYNNFVDMAKLLLQYHANPNARTELGWTPL 119
            |..:||::.||.:|...|..||.:|.|.|||||||||:..:|:.:.|:...|:.:|.|..|||||
Human    81 AAEKNRLTTVRRLLSEKATHVNTRDEDEYTPLHRAAYSGHLDIVQELIAQGADVHAVTVDGWTPL 145

  Fly   120 HSACKWNNADCAHLLLQFGADVNAESDGKQTPLHITATVSNCRNTATVLLLDRYIQPRKENNSEE 184
            ||||||||...|..|||..||:||::.|..||||:.|...:.::|..:||::||::|..:||.||
Human   146 HSACKWNNTRVASFLLQHDADINAQTKGLLTPLHLAAGNRDSKDTLELLLMNRYVKPGLKNNLEE 210

  Fly   185 LASVIARRTGMSFPIFE 201
            .|..|||||.:...:||
Human   211 TAFDIARRTSIYHYLFE 227

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ankrd49	NP_609735.1	ANKYR	<52..>194	CDD:440430	69/141 (49%)
		ANK repeat	52..79	CDD:293786	11/26 (42%)
		ANK repeat	81..112	CDD:293786	14/30 (47%)
		ANK repeat	114..144	CDD:293786	20/29 (69%)
		ANK repeat	147..180	CDD:293786	12/32 (38%)
ANKRD49	NP_060174.2	ANK 1	73..103		11/29 (38%)
		ANKYR	<77..>218	CDD:440430	67/140 (48%)
		ANK repeat	78..105	CDD:293786	11/26 (42%)
		ANK repeat	107..138	CDD:293786	14/30 (47%)
		ANK 2	107..136		13/28 (46%)
		ANK repeat	140..170	CDD:293786	20/29 (69%)
		ANK 3	140..169		19/28 (68%)
		ANK 4	173..206		12/32 (38%)