Protein Alignment CG3491 and Sbno2

DIOPT Version :10

• Sequence 1: NP_609731.1
• Gene: CG3491 / 34870
• FlyBaseID: FBgn0028887
• Length: 1801
• Species: Drosophila melanogaster
• Sequence 2: NP_001426502.1
• Gene: Sbno2 / 314619
• RGDID: 1307194
• Length: 1351
• Species: Rattus norvegicus
• Alignment Length: 1305
• Identity: 566/1305 - (43%)
• Similarity: 747/1305 - (57%)
• Gaps: 171/1305 - (13%)

  Fly   557 PPQPAIPPQPAI----------------PPA-PAYCMANKTMDTGMSSVVQMANNPLASTQHHAL 604
            ||....||...|                ||. |.:...|:..   :||...:.......|.:...
  Rat    13 PPHELPPPGGGIQLQNRLLHCPWWGSFSPPLYPTFSSENQQF---VSSTPFLGGQSCPETSYPTT 74

  Fly   605 PQVPIVTRLKVDQGEDVSV--------KFTTGLDGLI---TNVQLLPSTMAMGQPTVKATELESF 658
            ..||.......|..:|.|.        .|::.:|.|.   .....||:......||:......|.
  Rat    75 ATVPSFFSKSSDFPQDPSCLEDLSNASVFSSSVDSLSDIPDTPDFLPADSLNEVPTIWDVSTTST 139

  Fly   659 TAQQLNMLLQSGHPYLSLPMTNSGVPGAVLQETLQTKDAGFPSEQAVEDEEVDYEEIGVADTFAA 723
            |..:|.:   ...|:.:|....:.|....|..:.|:...  |.|:..|||| :.||:|.|:|:|.
  Rat   140 TRDKLFL---PSVPFSALEDPVTAVSSTPLLVSYQSHSQ--PEEEEGEDEE-EAEELGHAETYAD 198

  Fly   724 YWPSKLKFGRAHPDPVVETATLSSVELPNINYQLALPSKTTECLSALQLEAVVYACQAHEQILPS 788
            |.|||.|.|:.|||.||||:|||||..|:|.|.||||:.....||||||||:.||||.||.:|||
  Rat   199 YVPSKSKIGKQHPDRVVETSTLSSVPPPDITYTLALPTSDNGTLSALQLEAITYACQQHEVLLPS 263

  Fly   789 GDRAGFLLGDGAGVGKGRTIAGIIFDNYLKGRKRALWVSVSSDLKFDAERDLADIGAHEKIRVAT 853
            |.|||||:|||||||||||:||||.:|||:|||:|||.|.|:|||:||||||.||.| ..|.|..
  Rat   264 GQRAGFLIGDGAGVGKGRTVAGIIVENYLRGRKKALWFSASNDLKYDAERDLRDIEA-PGIAVHA 327

  Fly   854 INKFKYSPIDSEENENFKRGVIFCTYTALIGESMTTNSKYKTRFRQLTNWLGKKFEGVIVFDECH 918
            ::|.||.  |:..:|    ||:|.||:||||||. ...:::||.||:..|.|:.|:|||||||||
  Rat   328 LSKIKYG--DNTTSE----GVLFATYSALIGESQ-AGGQHRTRLRQILQWCGEAFDGVIVFDECH 385

  Fly   919 KAKNLSLMNVGKSTKTGTTVLDLQKLLPNARVVYASATGASEPRNMAYMVRLGLWGPGTAYPEFY 983
            ||||.|      |||.|..|||||..||.|||||||||||||||||.||.|||:||.||.:..|.
  Rat   386 KAKNAS------STKMGKAVLDLQNKLPQARVVYASATGASEPRNMIYMSRLGIWGEGTPFRTFE 444

  Fly   984 EFVNAVEKRGIGAMEIVAMDMKLRGTYIARQLSFKDVSFRIEEVNMSKEFRKSYNLSAELWADIH 1048
            ||::|:||||:|||||||||||:.|.||||||||..|:|||||:.:|..|.:.||.:|.|||:..
  Rat   445 EFLHAIEKRGVGAMEIVAMDMKVSGMYIARQLSFSGVTFRIEEIPLSPVFEQVYNRAARLWAEAL 509

  Fly  1049 KKFQKACRLMCVENRVQKIITCQFWCAHQRFFKNLCIASKVNHVVKMTRQATRMGKAVVIGLQST 1113
            ..||:|...:.:|:|  |.:..|||.|||||||.||||:||:.:|::.:|.....|.||||||||
  Rat   510 SVFQQAADWIGLESR--KSLWGQFWSAHQRFFKYLCIAAKVHRLVELAQQELSRDKCVVIGLQST 572

  Fly  1114 GESRTLEHLERHHGKLNSFVSTAKMIIQSFVEKHFPAPKRDSFHHLLNTGEFEPEARSRPPKQKK 1178
            ||:||.|.|:.:.|:|:.|||.|:.:..|.::||||:.:|               .|.|...::|
  Rat   573 GEARTREVLDENEGRLDCFVSAAEGVFLSLIQKHFPSTRR---------------RRDRGGGKRK 622

  Fly  1179 SKMNTDWVEDDMDAEAGESDIEMYERSCTAAVEKIKSGQKRRGRPPKADKVEKITMQE----RIL 1239
                                                  ::.|||.|||   .::|::.    ||.
  Rat   623 --------------------------------------RRPRGRGPKA---SRLTLEAAGVIRIS 646

  Fly  1240 EHLCNNMREQD-NEDESTNTSDNTKVKVNIT------------------ERD------VERCINM 1279
            :   .:..|.| ..|...|:|..:.|..::.                  :||      :||...:
  Rat   647 D---GSSTESDAGLDSDFNSSPESLVDDDVVIVDAPTLPTDDRGPLYPLQRDLQGPGVLERVERL 708

  Fly  1280 REMLLEKIDVLGRKLPPNTLDKLISELGGTNLVAEMTGRRGRVVRTEYDGYKYEPRCENDSTMDL 1344
            ::.||.|:..|||:||.||||:||.:|||...|||||||:||||........:|.|.|...::|.
  Rat   709 KQGLLAKVRALGRELPVNTLDQLIHQLGGPECVAEMTGRKGRVVSRPDGSVVFESRAEQGLSIDH 773

  Fly  1345 VNYREKQRFMDGSKHVAIISEAASSGISLQSDKRVSNQRRRLHITLELPWSADRAIQQFGRTHRS 1409
            ||.|||||||.|.|.|||||||:|||:|||:|:||.|||||:|:|||||||||||||||||||||
  Rat   774 VNLREKQRFMSGEKLVAIISEASSSGVSLQADRRVQNQRRRVHMTLELPWSADRAIQQFGRTHRS 838

  Fly  1410 NQVNAPEYVFVITDLAGERRFASTVAKRLESLGALTQGDRRATDARDLSQFNIDNSIGRSALENV 1474
            |||:||||||:|::|||||||||.||||||||||||.||||||::||||::|.:|..|..||..|
  Rat   839 NQVSAPEYVFLISELAGERRFASIVAKRLESLGALTHGDRRATESRDLSKYNFENKYGARALSRV 903

  Fly  1475 MQQL---TSNKPLDRSQVPQSYKGN---FIYDCCVAMAGVGMINVREENKVKVFTVEKDSNNISK 1533
            :..:   |:|    |..:||.|.|.   |..|....:..||:.:  .|::.....||||. :|:|
  Rat   904 LATIMGQTNN----RVPLPQGYPGGDAAFFRDMKQGLLSVGIGS--RESRSGCLDVEKDC-SITK 961

  Fly  1534 FLNRILGCRVEVQNALFKFFLDKMYSLIMQMKRTGRFDLGILDLDAHGASVKSIKLMRFIRKHAT 1598
            |||||||..|..|||||::|.|....||...|:.||:|:|||||......:.......|:.....
  Rat   962 FLNRILGLEVHKQNALFQYFSDTFDHLIEIDKKEGRYDMGILDLAPGINEIHEESQQVFLAPGHP 1026

  Fly  1599 GTAATELHTVTVERGMSFETALAK-YRKEGQYEHEGFYILQKRRQNKNSAILCLQAPSNSSDVSN 1662
            .......:.::|:|||.:|.|..: ...:|.|  :|||:..|.|.:|.|   ||.|..|..|.
  Rat  1027 QDGQVVFYKISVDRGMKWEEAFTRSLELKGPY--DGFYLSYKVRGSKTS---CLLAEQNRGDY-- 1084

  Fly  1663 GKINLQIYRPNTGPQVRLETHASISSRYVKVSPEEAQTYWVQQYELCLNMCSHLYWNRTCPMPTG 1727
                ..:|:||.|.|.:|||..::..::.:|:||||:..|...|.|.|..|||..||:.|.:...
  Rat  1085 ----FTVYKPNIGRQSQLETLDNLCRKFHRVTPEEAREPWESSYALSLEHCSHTTWNQRCRLAQE 1145

  Fly  1728 ---CEVGLRMRTYHVLSGLMLPIWDRIELII--VNSGHKIQIIRMKTDANKKIVGTVVPPAVYDD 1787
               |..|||:|.:::|.|.:|.:|.||..::  |:|...:||:|:||...||.||..:|......
  Rat  1146 GKCCAQGLRLRHHYMLCGALLRVWGRIAAVMADVSSSSYLQIVRLKTKDKKKQVGIKIPEGCVHR 1210

  Fly  1788 LVADL 1792
            ::.:|
  Rat  1211 VLQEL 1215

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3491	NP_609731.1	AAA_34	737..1038	CDD:464010	190/300 (63%)
		Helicase_C_4	1297..1576	CDD:464009	166/284 (58%)
Sbno2	NP_001426502.1	None