Protein Alignment CG3491 and Sbno1

DIOPT Version :8

• Sequence 1: NP_609731.1
• Gene: CG3491 / 34870
• FlyBaseID: FBgn0028887
• Length: 1801
• Species: Drosophila melanogaster
• Sequence 2: NP_001074672.1
• Gene: Sbno1 / 243272
• MGIID: 2384298
• Length: 1391
• Species: Mus musculus
• Alignment Length: 1442
• Identity: 626/1443 (43%)
• Similarity: 831/1443 (58%)
• Gaps: 207/1443 (14%)

  Fly   460 DSLFTTD----ELACPPPP------PLAKIPTNLTVERPHSRLSDPKKIESDIDARLQAELDSLP 514
            :.||..|    .||.|.||      ||:.:...|..|
Mouse    21 NDLFDVDGGDAGLATPTPPSVQQSVPLSALELGLETE---------------------------- 57

  Fly   515 MVAVPADENIEPLGKTDQHFSVPTNKNLSENKAFPKPNQVCIPPQPAIPPQPAIPPAPAYCMANK 579
             .|||..:..||:       |.|...|:.:.                       ||:....:.|:
Mouse    58 -AAVPVKQEPEPM-------STPALLNVRQQ-----------------------PPSTTTFVLNQ 91

  Fly   580 --TMDTGMSSVVQMANNPLASTQHHALPQVPIVTRLKVDQGEDVSVKFTTGLDGLITNVQLLPST 642
              .:.| :.|.:.|...|.|:|....      :|..|..|                |.....||.
Mouse    92 INQLPT-LGSTIVMTKTPPATTNRQT------ITLTKFIQ----------------TTANTRPSV 133

  Fly   643 MA-------MGQPTVKATELESFTA-QQLNMLLQSGHP-YLSLPMTNSGVP---GAVLQETLQTK 695
            .|       ...|:....:|:.... ..||.|::...| .::.|:..:...   |||.:|:...:
Mouse   134 SAPAVRNAMPAAPSKDQVQLKDLLKNNSLNELMKLKPPANIAQPVATAATDVSNGAVKKESSNKE 198

  Fly   696 DA----------GFPSEQAV-------EDEEVDYEEIGVADTFAAYWPSKLKFGRAHPDPVVETA 743
            .|          .|.....|       |.||.|.||:|.|:|:|.|.|.|||.|..|||.||||:
Mouse   199 VARIWINDMKMRSFSPTMKVPVVKEEDEPEEEDEEEMGHAETYAEYMPIKLKIGLRHPDAVVETS 263

  Fly   744 TLSSVELPNINYQLALPSKTTE--CLSALQLEAVVYACQAHEQILPSGDRAGFLLGDGAGVGKGR 806
            :||||..|::.|:.::..:|.:  .|||||||||.||.|.||..||:|||||||:||||||||||
Mouse   264 SLSSVTPPDVWYKTSISEETIDNGWLSALQLEAVTYAAQQHETFLPNGDRAGFLIGDGAGVGKGR 328

  Fly   807 TIAGIIFDNYLKGRKRALWVSVSSDLKFDAERDLADIGAHEKIRVATINKFKYSPIDSEENENFK 871
            ||||||::|||..||||||.|||:|||:||||||.|||| :.|.|.::|||||..|.|:.|.:.|
Mouse   329 TIAGIIYENYLLSRKRALWFSVSNDLKYDAERDLRDIGA-KNILVHSLNKFKYGKISSKHNGSVK 392

  Fly   872 RGVIFCTYTALIGESMTTNSKYKTRFRQLTNWLGKKFEGVIVFDECHKAKNLSLMNVGKSTKTGT 936
            :||||.||::|||||. :..|||||.:||.:|.|..|:||||||||||||||..:...|.||||.
Mouse   393 KGVIFATYSSLIGESQ-SGGKYKTRLKQLLHWCGDDFDGVIVFDECHKAKNLCPVGSSKPTKTGL 456

  Fly   937 TVLDLQKLLPNARVVYASATGASEPRNMAYMVRLGLWGPGTAYPEFYEFVNAVEKRGIGAMEIVA 1001
            .||:||..||.||||||||||||||||||||.|||:||.||.:.||.:|:.|||:||:|||||||
Mouse   457 AVLELQNKLPKARVVYASATGASEPRNMAYMNRLGIWGEGTPFREFSDFIQAVERRGVGAMEIVA 521

  Fly  1002 MDMKLRGTYIARQLSFKDVSFRIEEVNMSKEFRKSYNLSAELWADIHKKFQKACRLMCVENRVQK 1066
            |||||||.||||||||..|:|:||||.:|:.:.|.||.:.:||....::||:|..|:..|.|::|
Mouse   522 MDMKLRGMYIARQLSFTGVTFKIEEVLLSQSYVKMYNKAVKLWVIARERFQQAADLIDAEQRMKK 586

  Fly  1067 IITCQFWCAHQRFFKNLCIASKVNHVVKMTRQATRMGKAVVIGLQSTGESRTLEHLERHHGKLNS 1131
            .:..|||.|||||||.|||||||..||::.|:..:.||.||||||||||:||||.||...|:||.
Mouse   587 SMWGQFWSAHQRFFKYLCIASKVKRVVQLAREEIKNGKCVVIGLQSTGEARTLEALEEGGGELND 651

  Fly  1132 FVSTAKMIIQSFVEKHFPAPKRDSFHHLLNTGEFEP----EARSRPPKQKKSKMN---------- 1182
            ||||||.::||.:|||||||.|...:.||......|    ..|..|.|:.|.|..
Mouse   652 FVSTAKGVLQSLIEKHFPAPDRKKLYSLLGIDLTAPSNNSSPRDSPCKENKIKKRKGEEITREAK 716

  Fly  1183 --------TDWVEDDMDAEA----GESDIEMYERSCTAAVEK------------------IKSGQ 1217
                    |....||..:|:    .|||.|..:...:...:.                  |:...
Mouse   717 KARKVGGLTGSSSDDSGSESVSDNDESDYESSKNMSSGDDDDFNPFRDESSEDNEDDPWLIRKDH 781

  Fly  1218 KRRGRPPKADKVEKITMQERILEHLCNNMR-----------EQDNEDESTNTSDNTKVKVNITER 1271
            |:.....|...::..::|..:|.....:.|           ..::...::|::.|:.:   :|.:
Mouse   782 KKSKDKKKKKSIDPDSIQSALLASGLGSKRPSFSSAPVISPASNSAPANSNSNSNSSL---VTSQ 843

  Fly  1272 D-VERCINMREMLLEKIDVLGRKLPPNTLDKLISELGGTNLVAEMTGRRGRVVRTEYDGYKYEPR 1335
            | |||...|::.||:|::.|...|||||||:||.||||...|||||||:||||..:.....||.|
Mouse   844 DAVERAQQMKKDLLDKLEKLAEDLPPNTLDELIDELGGPENVAEMTGRKGRVVSNDDGSISYESR 908

  Fly  1336 CENDSTMDLVNYREKQRFMDGSKHVAIISEAASSGISLQSDKRVSNQRRRLHITLELPWSADRAI 1400
            .|.|..::::|..||||||||.|::||||||||||||||:|:|..|||||:|:||||||||||||
Mouse   909 SELDVPVEILNITEKQRFMDGDKNIAIISEAASSGISLQADRRAKNQRRRVHMTLELPWSADRAI 973

  Fly  1401 QQFGRTHRSNQVNAPEYVFVITDLAGERRFASTVAKRLESLGALTQGDRRATDARDLSQFNIDNS 1465
            ||||||||||||.||||||:|::||||:||||.||||||||||||.||||||::||||:||.||.
Mouse   974 QQFGRTHRSNQVTAPEYVFLISELAGEQRFASIVAKRLESLGALTHGDRRATESRDLSRFNFDNK 1038

  Fly  1466 IGRSALENVMQQLTSNKPLDRSQV--PQSYKGNFIYDCCVAMAGVGMINVREENKVKVFTVEKDS 1528
            .||:|||.||:.:.:   ||...|  |..|.|.|..|....:.|||:|||  |::..:.|::||.
Mouse  1039 YGRNALEIVMKSIVN---LDSPMVSPPPDYPGEFFKDVRQGLIGVGLINV--EDRSGILTLDKDY 1098

  Fly  1529 NNISKFLNRILGCRVEVQNALFKFFLDKMYSLIMQMKRTGRFDLGILDLDAHGASVKSIKLMRFI 1593
            |||.||||||||..|..|||||::|.|.:.:::...|:.||:|:|||||.:....|:...:.:|:
Mouse  1099 NNIGKFLNRILGMEVHQQNALFQYFADTLTAVVQNAKKNGRYDMGILDLGSGDEKVRKSDVKKFL 1163

  Fly  1594 RKHATGTAATELHTVTVERGMSFETALAKYRKEGQYEHEGFYILQKRRQNKNSAILCLQAPSNSS 1658
            ....:.:...||:|::||||||:|.| .|...|.....:|||:..:.|.||.:|||.       .
Mouse  1164 TPGYSTSGHVELYTISVERGMSWEEA-TKIWAELTGPDDGFYLSLQIRNNKKTAILV-------K 1220

  Fly  1659 DVSNGKINLQIYRPNTGPQVRLETHASISSRYVKVSPEEAQTYWVQQYELCLNMCSHLYWNRTC- 1722
            :|:..|....|||||||.|::||.:|.:..:|.||..::|..:|:.||....:.|:|.||...|
Mouse  1221 EVNPKKKLFLIYRPNTGKQLKLEIYADLKKKYKKVVSDDALVHWLDQYNSSADTCTHAYWRGNCK 1285

  Fly  1723 --PMPTGCEVGLRMRTYHVLSGLMLPIWDRIELIIVN-SGH--KIQIIRMKTDANKKIVGTVVPP 1782
              .:...||:|||.|||:||.|.:|.:|.::|.::.: ||.  |:||:|::|:..::|||.::|.
Mouse  1286 KASLGLVCEIGLRCRTYYVLCGSVLSVWTKVEGVLASVSGTNVKMQIVRLRTEDGQRIVGLIIPA 1350

  Fly  1783 AVYDDLVADLST 1794
            .....||..|||
Mouse  1351 NCVSPLVNLLST 1362

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3491	NP_609731.1	AAA_34	737..1038	CDD:290583	199/303 (66%)
		DEXDc	759..986	CDD:214692	152/229 (66%)
		Helicase_C_4	1297..1576	CDD:290582	174/281 (62%)
Sbno1	NP_001074672.1	AAA_34	257..559	CDD:316395	200/304 (66%)
		Helicase_C_4	870..1146	CDD:316394	174/281 (62%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
eggNOG	1	0.900				E1_KOG1513
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900				OOG5_129178
Panther	1	1.100			O	PTHR12706
Phylome	1	0.910		0.750	Consistency score
RoundUp	0	0.000	Not matched by this tool.
TreeFam	1	0.960
	5	4.770