DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3491 and sbno2

DIOPT Version :9

Sequence 1:	NP_609731.1	Gene:	CG3491 / 34870	FlyBaseID:	FBgn0028887	Length:	1801	Species:	Drosophila melanogaster
Sequence 2:	XP_017952368.2	Gene:	sbno2 / 100497013	XenbaseID:	XB-GENE-486292	Length:	1339	Species:	Xenopus tropicalis

Alignment Length:	1308	Identity:	561/1308 - (42%)
Similarity:	755/1308 - (57%)	Gaps:	202/1308 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   559 QPAIPPQPAIPPA----------PAYCMANKTMDTGMSSVVQMANNPLASTQHHALPQVPIVTRL 613
            ||:.|......||          ||:|:.:.::   .|......|.|..|.....|
Frog    35 QPSQPDSETATPAGNLWTHNTYSPAHCLPHASL---TSPSQPFLNYPAHSNFFQDL--------- 87

  Fly   614 KVDQGEDVSVKFTTGLDGL---------ITNVQLLPSTMAMGQPTVKATELESF-TAQQLNML-- 666
                   .|.:|::...||         :||.....|.::....::.....:.| |.:.|:.:
Frog    88 -------ASQRFSSSFSGLSYCDFQEPSLTNDFSNQSILSSSPDSLSDINTQDFLTIEGLDRVPT 145

  Fly   667 --------LQSGHPYLSLPMTNSGVPGAVLQETLQ------TKDAGFPSEQAVEDEEVDYEEIGV 717
                    ....:|:|..|  |..:|.....|.||      :.....|.|:..|||  |.||:|.
Frog   146 LWDISTPPQDFSNPHLFHP--NPPLPALETFEDLQAIINTPSTQERLPPEEEEEDE--DTEELGH 206

  Fly   718 ADTFAAYWPSKLKFGRAHPDPVVETATLSSVELPNINYQLALPSKTTE--CLSALQLEAVVYACQ 780
            .:|:|.|.|||.|.||.|||.||||:|||||..|:|.|.|:|||...|  .|||||||::|||||
Frog   207 TETYADYVPSKSKIGRQHPDRVVETSTLSSVPPPDITYSLSLPSDVIEQGFLSALQLESIVYACQ 271

  Fly   781 AHEQILPSGDRAGFLLGDGAGVGKGRTIAGIIFDNYLKGRKRALWVSVSSDLKFDAERDLADIGA 845
            .||.|||||.|||||:|||||||||||::|||.:|:.||||:|||.|||:||:.||||||.||.|
Frog   272 QHEVILPSGQRAGFLIGDGAGVGKGRTVSGIILENFSKGRKKALWFSVSNDLRCDAERDLRDINA 336

  Fly   846 HEKIRVATINKFKYSPIDSEENENFKRGVIFCTYTALIGESMTTNSKYKTRFRQLTNWLGKKFEG 910
            .. |.|..:||.||....|.|      ||:|.||:||||||. ...:::||.:|:.:|.|:||:|
Frog   337 GH-IAVHALNKIKYGDTSSSE------GVLFATYSALIGESQ-AGGQHRTRIKQIRDWCGEKFDG 393

  Fly   911 VIVFDECHKAKNLSLMNVGKSTKTGTTVLDLQKLLPNARVVYASATGASEPRNMAYMVRLGLWGP 975
            ||||||||||||.|      |||.|..||:||..||.||||||||||||||:||.||.|||:||.
Frog   394 VIVFDECHKAKNAS------STKMGRAVLELQNNLPMARVVYASATGASEPKNMIYMSRLGIWGE 452

  Fly   976 GTAYPEFYEFVNAVEKRGIGAMEIVAMDMKLRGTYIARQLSFKDVSFRIEEVNMSKEFRKSYNLS 1040
            ||::..|.:|::|:||||:|||||||||||:.|.||||||||..|:|||||:.:.:.::..||.:
Frog   453 GTSFSTFDDFLHAIEKRGVGAMEIVAMDMKVSGMYIARQLSFSGVTFRIEEIPLEESYKHMYNRA 517

  Fly  1041 AELWADIHKKFQKACRLMCVENRVQKIITCQFWCAHQRFFKNLCIASKVNHVVKMTRQATRMGKA 1105
            |:|||:....||.|...:.:|:|  |.:..|||.|||||||.|||||||..:|.:.:|....||.
Frog   518 AQLWAEALVVFQTAADWLGLESR--KSLWGQFWSAHQRFFKYLCIASKVQRLVTLVKQELAKGKC 580

  Fly  1106 VVIGLQSTGESRTLEHLERHHGKLNSFVSTAKMIIQSFVEKHFPAPKRDSFHHLLNTGEFEPEAR 1170
            ||||||||||:||.|.::.:.|.|:.|||.|:.:.:|.:.||||:.||..        |...:.|
Frog   581 VVIGLQSTGEARTREVMDENDGHLDCFVSAAEGVFRSLILKHFPSTKRKR--------EKAMQKR 637

  Fly  1171 SRPPKQKKSKMNTDWV-------EDDMDAEAG-ESDI----EMYERSCTAAVEKIKSGQKRRGRP 1223
            .|..|.:..||:...:       |...|:|.| :||.    |.::......:|:..:|.....|.
Frog   638 KRRGKPRSGKMSRGDLGLIRISEESSSDSEGGLDSDFNSSPESFQDDDVIYIERTMNGMTLPDRV 702

  Fly  1224 PKADKVEKITMQERILEHLCNNMREQDNEDESTNTSDNTKVKVNITERDVERCINMREMLLEKID 1288
            |:.|:                                                  ::..||.|::
Frog   703 PEVDR--------------------------------------------------LKMELLAKVE 717

  Fly  1289 VLGRKLPPNTLDKLISELGGTNLVAEMTGRRGRVVRTEYDGYKYEPRCENDSTMDLVNYREKQRF 1353
            .||::||.||||:||.:.||...|||||||:|||||......::|.|.|.:.::|.||.|||:||
Frog   718 TLGKELPLNTLDELIDQFGGPEKVAEMTGRKGRVVRKSDRTVQFESRAEQNLSIDNVNLREKERF 782

  Fly  1354 MDGSKHVAIISEAASSGISLQSDKRVSNQRRRLHITLELPWSADRAIQQFGRTHRSNQVNAPEYV 1418
            |:|.|.|||||||:|||||||:||||.|:|||:|:||||||||||||||||||||||||:|||||
Frog   783 MNGEKLVAIISEASSSGISLQADKRVPNKRRRVHMTLELPWSADRAIQQFGRTHRSNQVSAPEYV 847

  Fly  1419 FVITDLAGERRFASTVAKRLESLGALTQGDRRATDARDLSQFNIDNSIGRSALENVMQQLTSNKP 1483
            |:|::||||:||||.||||||||||||.||||||::||||::|.:|..|..|||.::..:
Frog   848 FLISELAGEKRFASIVAKRLESLGALTHGDRRATESRDLSKYNFENKYGTRALEQILSAI----- 907

  Fly  1484 LDRSQ----VPQSYKGN---FIYDCCVAMAGVGMINVREENKVKVFTVEKDSNNISKFLNRILGC 1541
            |:::|    .|:.|.|:   |..:....:..|| |..||   .|...::|:. :::|||||:||.
Frog   908 LNQTQREVPPPRDYPGSSKEFFQEIKQGLLSVG-ICCRE---TKHNAIDKEC-SVTKFLNRMLGL 967

  Fly  1542 RVEVQNALFKFFLDKMYSLIMQMKRTGRFDLGILDLDAHGASVKSIKLMRFIRKHATGTAATELH 1606
            .|..||:||:||.|....||.:.|:.|::|:||||| |.|...        |.:.:..|..|..|
Frog   968 EVHKQNSLFQFFSDTFDYLIEKDKKEGKYDMGILDL-APGVDE--------IYQESKETFMTPGH 1023

  Fly  1607 ---------TVTVERGMSFETALAKYR--KEGQYEHEGFYILQKRRQNKNSAILCLQAPSNSSDV 1660
                     |::|:||||:..||.||:  |:   :|||||:..:.|....||:|        ::.
Frog  1024 PQDGQVVFYTISVDRGMSWAKALEKYQNLKD---QHEGFYLSYRARGTMFSAVL--------AEH 1077

  Fly  1661 SNGKINLQIYRPNTGPQVRLETHASISSRYVKVSPEEAQTYWVQQYELCLNMCSH-LYWNRTCP- 1723
            .:||. ..:|:||.|.|.:.|...|:.|:|.|||||||..:|..||...|:.||| :..|..|.
Frog  1078 RHGKY-FNLYKPNIGRQSQAEALDSLLSKYHKVSPEEAMEHWEDQYNFSLHNCSHTMCRNGNCKG 1141

  Fly  1724 MPTG--CEVGLRMRTYHVLSGLMLPIWDRIELII--VNSGHKIQIIRMKTDANKKIVGTVVPPAV 1784
            :..|  |..|||:|.|::|.|.:|.:|.|:..:|  :.|...:||:|:||....|.||..:|.:.
Frog  1142 LQQGKKCVQGLRLRYYYMLCGSLLRVWSRMASVISDITSSSYLQIVRLKTKDKHKQVGIKIPESC 1206

  Fly  1785 YDDLVADL 1792
            .|.:..:|
Frog  1207 VDKVKEEL 1214

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3491	NP_609731.1	AAA_34	737..1038	CDD:290583	186/302 (62%)
		DEXDc	759..986	CDD:214692	140/228 (61%)
		Helicase_C_4	1297..1576	CDD:290582	159/285 (56%)
sbno2	XP_017952368.2	AAA_34	226..516	CDD:404713	187/303 (62%)
sbno2	XP_017952368.2	Helicase_C_4	726..1002	CDD:404712	159/285 (56%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D112455at33208
OrthoFinder	1	1.000	-	-		FOG0002373
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12706
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1569
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.110