Protein Alignment CSN1a and csn1

DIOPT Version :10

• Sequence 1: NP_609720.1
• Gene: CSN1a / 34857
• FlyBaseID: FBgn0028838
• Length: 364
• Species: Drosophila melanogaster
• Sequence 2: NP_596680.1
• Gene: csn1 / 2540352
• PomBaseID: SPBC215.03C
• Length: 422
• Species: Schizosaccharomyces pombe
• Alignment Length: 347
• Identity: 90/347 - (25%)
• Similarity: 147/347 - (42%)
• Gaps: 45/347 - (12%)

  Fly     3 NGEETMLHLPSYADRYTDIPRLIRLKFIAQVCPELSVLALELALNHVK-TTYNVKLYDELYKTL- 65
            |.||    |..|.|.|....::.|..|:|:....|....:..|:..:| .|||::||..|::..
pombe     8 NQEE----LKRYLDEYGVWSKIFRALFVARNSKPLRSFCVHYAIKELKEKTYNLELYQSLFEEFQ 68

  Fly    66 -CVEVDRKYPNQSKGNEELHTTGGSEPSTSSGRGRVVVPYDSYWVEDNIMEATLMLQELDAELNF 129
             |.|           ||:|                     |..|||.........|::|..||..
pombe    69 DCFE-----------NEQL---------------------DVEWVESVTFHRKQNLEQLRRELKA 101

  Fly   130 KKSNSGSSYVRRILEEIGDHHEKSGNLQMAVKFYARARPYCTSSENVINMFRNLIRVSIYMENWW 194
            .|:|.....:|....::.......|....|::.||:.|.|||::..:.::...|:|:||::.|:.
pombe   102 YKNNLIRESIRAAQLDLASFFADVGQFDSALRSYAKVREYCTNAGQIAHLSLELMRISIWIGNYS 166

  Fly   195 HVLTYIDEAKQYAYGFENLAQEVPARLSCVAGLAHLGLKIYKSAAQYFLSTPYGRYDYDKIVAPE 259
            |||.:...||...    :.|.|:.:.:....|||:..|..|:.|..:||.....  ..|.|:...
pombe   167 HVLAFGSRAKSTV----SAAMELTSPIYAYCGLANFCLGDYEEALAHFLKVETD--TSDGIITKT 225

  Fly   260 DVTLYAGLCALATFDRETLQLNAINSEAFKPFFQLSPKMWTILAKFYAGEFDACMTLLREIENHV 324
            |:::|..|||||.:|.:.|......:|.|.....|.|.:...|......::...:..|::.....
pombe   226 DISVYISLCALACWDHKRLIQELERNEEFNALSDLDPSLRRCLQAKCNRKYSLLLDTLQQNAQDY 290

  Fly   325 RLDVYLSPHVSALYDLIMARML 346
            .||:||:|.::.|:.||..|.|
pombe   291 SLDMYLAPQLTNLFSLIRERSL 312

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CSN1a	NP_609720.1	RPN7	105..279	CDD:431387	49/173 (28%)
csn1	NP_596680.1	RPN7	77..246	CDD:431387	50/174 (29%)
		PCI	262..365	CDD:460195	13/51 (25%)